
DPD/DPYD Mutation Analysis near me in Gurgaon







The DPD/DPYD Mutation Analysis test detects mutations in the DPYD gene, which provides instructions for making the enzyme Dihydropyrimidine Dehydrogenase (DPD). This enzyme is essential for breaking down certain chemotherapy medicines like 5-Fluorouracil (5-FU) and Capecitabine. The test helps identify individuals who may have DPD deficiency, a condition that can cause severe or even life-threatening side effects when treated with standard doses of these medicines. Early detection allows doctors to adjust chemotherapy doses or choose alternative treatments for safer and more effective care. This test is widely available with Tata 1mg labs at an affordable price in Gurgaon.








What does DPD/DPYD Mutation Analysis measure?
The DPD/DPYD Mutation Analysis test examines the DPYD gene for mutations that affect the production or function of the Dihydropyrimidine Dehydrogenase (DPD) enzyme.
This enzyme is crucial for metabolizing chemotherapy medicines like 5-Fluorouracil and Capecitabine. When DPD activity is reduced or absent, the body cannot properly break down these medicines, leading to an increased risk of severe toxicity.
Normal result indicates no significant mutation and normal DPD enzyme activity, standard chemotherapy dosing is generally safe. Abnormal results suggest reduced or absent DPD enzyme activity. Dosage adjustment or an alternate chemotherapy regimen may be recommended.
By identifying these mutations, the test helps doctors tailor chemotherapy safely, minimizing side effects and improving treatment outcomes.





- Patil VM, Noronha V, Joshi A, Zanwar S, Ramaswamy A, Arya S, Mahajan A, Bhattacharjee A, Prabhash K. Dihydropyrimidine dehydrogenase mutation in neoadjuvant chemotherapy in head and neck cancers: Myth or reality? South Asian J Cancer. 2016 Oct-Dec;5(4):182-185.
- Cancer Research UK. DPD deficiency [Internet]. London: Cancer Research UK; updated 11 July 2023; [Accessed 04 Nov 2025]. Available from:
Other tests
- Comprehensive Gold Full Body Checkup with Smart Report in Gurgaon
- Comprehensive Silver Full Body Checkup with Smart Report in Gurgaon
- Good Health Gold Package with Smart Report in Gurgaon
- Urine R/M (Urine Routine & Microscopy) in Gurgaon
- HbA1c (Glycosylated Hemoglobin) in Gurgaon
- Thyroid Profile Total (T3, T4 & TSH) in Gurgaon
- LFT (Liver Function Test) in Gurgaon
- FBS (Fasting Blood Sugar) in Gurgaon
- KFT with Electrolytes (Kidney Function Test with Electrolytes) in Gurgaon
- Urine C/S (Urine Culture and Sensitivity) in Gurgaon
- Niva Bupa - Comprehensive Check-up - 74496 in Gurgaon
- CRP (C-Reactive Protein), Quantitative in Gurgaon
- Vitamin B12 in Gurgaon
- Magnesium in Gurgaon
- TW-EYGDS HC in Gurgaon
- Good Health Platinum Package with Smart Report in Gurgaon
- Senior Citizen Health Checkup with Smart Report, in Gurgaon
- Senior Citizen Essential Health Checkup with Smart Report in Gurgaon
- Men Advanced Plus Health Checkup with Smart Report in Gurgaon
- Men Advanced Health Checkup with Smart Report in Gurgaon
- Men Health Checkup Advanced with Smart Report, in Gurgaon
- Super Employee Health Check-up in Gurgaon
- PT INR (Prothrombin Time with INR) in Gurgaon
- Women Advanced Health Checkup with Smart Report in Gurgaon
- Women Health Checkup Advanced with Smart Report, in Gurgaon
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- PPBS (Postprandial Blood Sugar)
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid -19 test- RT PCR
- LFT (Liver Function Test)
- KFT (Kidney Function Test)
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid, Serum
- Vitamin B12
- CRP (C-Reactive Protein), Quantitative
- Urine C/S (Urine Culture and Sensitivity)
- Serum Electrolytes
- Serum Calcium
- Serum Creatinine
- Diabetes Screening (HbA1C & Fasting Sugar)
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hb (Hemoglobin)
- Complete Hemogram (CBC & ESR)





