
CD3 / CD4 / CD8 / CD45 Count









The CD3 / CD4 / CD8 / CD45 Count test is a blood test that measures the levels of several important immune cells in your body. It helps doctors check the health of your immune system, especially in conditions like immune deficiencies, autoimmune diseases, and certain cancers.













Understanding CD3 / CD4 / CD8 / CD45 Count
Your immune system is a complex network of cells that work together to protect you from illness. The CD3 / CD4 / CD8 / CD45 Count test focuses on different types of T-cells, which are a key part of this network. This test measures the levels of these cells by looking for specific markers on their surfaces.
- CD3: Found on all T-cells, this marker helps identify the total number of T-cells.
- CD4 (Helper T-cells): These cells help coordinate the immune response by activating other immune cells.
- CD8 (Cytotoxic T-cells): These "killer" cells are responsible for destroying infected or abnormal cells, such as those with viruses or cancer.
- CD45: This marker is present on all white blood cells, including T-cells. It helps identify and count the total number of lymphocytes.
- By measuring the percentages and absolute counts of these cells, as well as the CD4/CD8 ratio, your doctor can get a clear picture of your immune system’s health. Abnormal results can signal an underlying health issue. For instance, a low CD4 count is a known marker for HIV progression, while unusual ratios can be linked to autoimmune diseases or specific blood cancers.
Your doctor may suggest the CD3 / CD4 / CD8 / CD45 Count test if you have a condition that affects your immune system or if you are undergoing treatment that might suppress it.
No special preparation is needed for the CD3 / CD4 / CD8 / CD45 Count test. You should inform your doctor about any medications you are taking, as some may affect the results.
Test result ranges are estimates and may vary slightly between labs depending on their methods and guidelines. Always consult a doctor to understand your report correctly.
Please note: This is an outsourced test. The sample for this test is collected by TATA 1MG and processed at a NABL accredited partnered lab.
What does CD3 / CD4 / CD8 / CD45 Count measure?
Contains 8 testsThe CD3 / CD4 / CD8 / CD45 Count test measures the absolute counts and percentages of four key markers on your immune cells:
CD45: A general marker for all white blood cells
CD3: A marker for all T-cells
CD4: A marker for helper T-cells
CD8: A marker for cytotoxic T-cells. It also calculates the ratio of CD4 to CD8 cells.





FAQs related to CD3 / CD4 / CD8 / CD45 Count
- Rheinländer A, Schraven B, Bommhardt U. CD45 in human physiology and clinical medicine. Immunol Lett. 2018 Apr;196:22-32. [Accessed 12 Sep. 2025]. Available from:
- CD8 [Internet]. ScienceDirect; [Accessed 12 Sep. 2025]. Available from:
- Liu D, Hu X, Chen Z, Wei W, Wu Y. Key links in the physiological regulation of the immune system and disease induction: T cell receptor -CD3 complex. Biochem Pharmacol. 2024 Sep;227:116441. [Accessed 12 Sep. 2025]. Available from:
- Getting Tested for HIV [Internet]. CDC; 11 Feb. 2024 [Accessed 12 Sep. 2025]. Available from:
- Luckheeram RV, Zhou R, Verma AD, Xia B. CD4⁺T cells: differentiation and functions. Clin Dev Immunol. 2012;2012:925135. [Accessed 12 Sep. 2025]. Available from:
- Wu Z, Zheng Y, Sheng J, Han Y, Yang Y, Pan H, Yao J. CD3+CD4-CD8- (Double-Negative) T Cells in Inflammation, Immune Disorders and Cancer. Front Immunol. 2022 Feb 10;13:816005. [Accessed 12 Sep. 2025]. Available from:
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- Lipid Profile
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- LFT (Liver Function Test)
- KFT (Kidney Function Test)
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- Hb (Hemoglobin)
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