Brucella IgG & IgM Antibodies

Brucellosis is an infectious disease caused by the Brucella bacteria. It is typically transmitted to humans through direct contact with infected animals or by consuming unpasteurized dairy products such as milk, cheese, or butter. It is also known as “undulant fever” due to its characteristic pattern of rising and falling fever.

The Brucella IgG & IgM Antibodies test detects two different antibodies against Brucella. These antibodies are IgM, which appears early and signals a recent or active infection, and IgG, which develops later and may be seen in chronic infection when symptoms persist. 

The Brucella IgG & IgM Antibodies test is recommended when a doctor suspects brucellosis based on symptoms, exposure history, or risk factors. Common symptoms include recurrent or undulating fever, night sweats (sometimes with a strong odor), persistent fatigue, muscle and joint pain, backache, headache, and loss of appetite. This test is also advised if there is a history of contact with livestock, handling animal products, working in slaughterhouses or veterinary settings, or consuming unpasteurized milk, cheese, or other dairy products in regions where brucellosis is common. By detecting both IgM and IgG antibodies, this test may help differentiate between a current or recent infection and past exposure or chronic disease when combined with symptoms and other tests. It is also useful for monitoring treatment progress and checking for relapse after therapy. However, antibody levels may stay positive even after treatment; doctors may use repeat testing with symptoms/cultures. Early testing and diagnosis allow timely antibiotic treatment, which can prevent serious complications such as arthritis, hepatitis, endocarditis, or nervous system involvement.

No special preparation is required for this test. However, the doctor should be informed about all medications, supplements, or underlying illnesses, as these factors can affect the test results.

Laboratory test results may vary across laboratories. Do not self-medicate and always consult a doctor to understand the test results correctly. In some cases, repeat testing or additional confirmatory tests may be warranted.

Please note: This is an outsourced test. The sample is collected by TATA 1MG and processed at a NABL accredited partnered lab.