SGOT (Aspartate Aminotransferase)

SGOT, also known as aspartate aminotransferase (AST), is an enzyme involved in amino-acid metabolism and is present in several tissues, including the liver, heart, and skeletal muscles. When cells in these tissues are injured, AST can be released into the bloodstream, causing its blood level to increase. Therefore, an elevated AST level does not always indicate liver damage and needs to be interpreted along with other test results and clinical findings.

An SGOT (AST) test may be performed if you have symptoms or clinical findings that may suggest liver or other tissue injury, such as loss of appetite, abdominal pain or swelling, dark-coloured urine, unusual bruising, vomiting, or yellowing of the skin and eyes. However, an AST test alone cannot determine the cause or extent of liver damage. It may also be used to monitor changes in AST levels in people with known liver conditions or during follow-up. AST levels may also be monitored when certain medicines are being used that can affect the liver.

Usually, no special preparation is required for an SGOT test when it is performed alone. Eat and drink as per your usual routine unless your doctor or laboratory provides specific instructions.

Test result ranges are approximate and may differ slightly between labs depending on the methodology and laboratory guidelines. Talk to your doctor about your specific test results. Narrate your complete medical history to help the doctor correlate your clinical and laboratory findings. The test results will help them determine your medical condition, make recommendations for lifestyle modifications such as diet and exercise, decide whether or not medication will be required to manage your liver health, and formulate your overall treatment plan.