
Apolipoprotein - B










An Apolipoprotein - B test checks the amount of apolipoprotein B (Apo B) in the blood. Apo B is a protein that helps carry cholesterol and fats (triglycerides) through the body. This test is done to check how healthy the heart is. It also helps find out the risk of heart-related problems like heart attack and stroke.













Understanding Apolipoprotein - B
Apolipoprotein B, or Apo - B, is an essential protein that assists in transporting fats within the blood. It is primarily associated with low-density lipoprotein (LDL), or "bad cholesterol." Elevated levels of Apo - B may lead to plaque (fat buildup) in the arteries. This may raise the risk of heart attacks, strokes, and other heart conditions. That is why it is crucial to know the Apo-B level for maintaining heart health.
An Apolipoprotein - B test is useful when routine cholesterol tests are not providing sufficient information regarding heart health. Doctors might order this test if there are symptoms of heart issues, such as chest discomfort, shortness of breath, or rapid heartbeat. It can also be ordered if there are risk factors such as high blood pressure, high cholesterol, obesity, diabetes, or a family history of heart disease. This test also helps assess whether the treatment is effective in individuals with an existing heart condition. It can also be used to diagnose a very rare inherited disorder in which the body does not produce enough Apo B protein.
Overnight fasting for 8-12 hours is required for this test. Do not eat or drink anything except water before the test. Inform the doctor about any medicines or supplements being taken for heart problems, as they may affect test results. Always consult the doctor before making any changes to medication.
Test results can be slightly different depending on the lab. The doctor will explain what the result means. Based on the result, the doctor may plan a treatment or give advice on changes in lifestyle and medicines to manage the condition.
What does Apolipoprotein - B measure?
The Apolipoprotein - B test measures the level of Apo B in the blood. The protein helps in transporting fats and cholesterol within the body. Apo B is a central component of some fat-carrying particles in the blood, such as very low-density lipoprotein (VLDL), low-density lipoprotein (LDL), and chylomicrons. It binds to LDL or "bad" cholesterol, which may result in plaque developing in the blood vessels. This accumulation can lead to heart disease, which can become grave or life-threatening if left untreated.















FAQs related to Apolipoprotein - B
- Devaraj S, Semaan JR, Jialal I. Biochemistry, Apolipoprotein B. [Updated 2023 May 14]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan-. Available from:
- Behbodikhah J, Ahmed S, Elyasi A, Kasselman LJ, De Leon J, Glass AD, Reiss AB. Apolipoprotein B and Cardiovascular Disease: Biomarker and Potential Therapeutic Target. Metabolites. 2021 Oct 8;11(10):690. [Accessed 16 Jan. 2024]. Available from:
- Apolipoprotein B-100 [Internet]. Healthdirect; [Accessed 16 Jan. 2024]. Available from:
- Contois JH, Langlois MR, Cobbaert C, Sniderman AD. Standardization of Apolipoprotein B, LDL-Cholesterol, and Non-HDL-Cholesterol. J Am Heart Assoc. 2023 Aug;12(15):e030405. [Accessed 16 Jan. 2024]. Available from:
- Sniderman AD, Thanassoulis G, Glavinovic T, Navar AM, Pencina M, Catapano A, Ference BA. Apolipoprotein B Particles and Cardiovascular Disease: A Narrative Review. JAMA Cardiol. 2019 Dec 1;4(12):1287-1295. [Accessed 16 Jan. 2024]. Available from:
- Nayak P, Panda S, Thatoi PK, Rattan R, Mohapatra S, Mishra PK. Evaluation of Lipid Profile and Apolipoproteins in Essential Hypertensive Patients. J Clin Diagn Res. 2016 Oct;10(10):BC01-BC04. [Accessed 16 Jan. 2024]. Available from:
- What is heart disease? [Internet]. CDC; 15 May 2023 [Accessed 16 Jan. 2024]. Available from:
- Cardiovascular Risk Factors and Markers. A literature review. Vasculopathies. 19 Jan. 2003. [Accessed 16 Jan. 2024]. Available from:
- Thiriet M. Cardiovascular Risk Factors and Markers. Vasculopathies. 2019 Feb 19;8:91–198. [Accessed 16 Jan. 2024]. Available from:
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- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- PPBS (Postprandial Blood Sugar)
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid -19 test- RT PCR
- LFT (Liver Function Test)
- KFT (Kidney Function Test)
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid, Serum
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- CRP (C-Reactive Protein), Quantitative
- Urine C/S (Urine Culture and Sensitivity)
- Serum Electrolytes
- Serum Calcium
- Serum Creatinine
- Diabetes Screening (HbA1C & Fasting Sugar)
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hb (Hemoglobin)
- Complete Hemogram (CBC & ESR)






















