
Anti Streptolysin O Titer










The Anti Streptolysin O Titer is a blood test that measures the levels of antibodies against streptolysin O, a toxin produced by group A streptococcus bacteria. It helps diagnose recent streptococcal infections and related complications, such as rheumatic fever and acute glomerulonephritis.













Understanding Anti Streptolysin O Titer
The Anti Streptolysin O Titer test looks for antibodies in your blood that your body makes while fighting off Group A Streptococcus (GAS) bacteria. This bacteria can cause various infections including strep throat, scarlet fever, skin infections, cellulitis etc.
The Anti Streptolysin O Titer test helps identify a recent or past streptococcal infection. It is particularly useful in diagnosing complications that arise from streptococcal infections, such as rheumatic fever (a serious complication of untreated strep throat, affecting the heart, joints, brain and skin) and post-streptococcal glomerulonephritis (an inflammation of kidneys, following a streptococcal infection, leading to kidney damage), which can occur weeks after the initial infection.
This test is recommended for individuals showing symptoms of a recent streptococcal infection or related complications, including joint pain, skin rashes, fever, or kidney problems. The ASO levels can help tell whether a streptococcal infection might be responsible for these symptoms.
Elevated ASO titres can suggest that the body has mounted an immune response to a recent strep infection. However, ASO levels can sometimes be temporarily elevated in individuals due to other factors like long-term illnesses, other infections etc., or even in healthy individuals without any symptoms.
No special preparation is required for this test. However, inform your doctor about any medications, supplements or any underlying medical conditions you may have, as these factors could potentially affect the test results.
Lab test results may vary across laboratories. Abnormal test results require an expert interpretation; therefore, never try to self-medicate at home based solely on these results, and always consult a doctor for a proper understanding of the test results as the insights from this test helps doctors assess the severity of the infection and determine appropriate treatment plans.
What does Anti Streptolysin O Titer measure?
The Anti Streptolysin O Titer test measures the level of antibodies in the blood that target streptolysin O, a homogeneous exotoxin produced by the Streptococcus pyogenes bacteria. When the body is infected with this bacteria, it produces antibodies, including ASO, as part of the immune response to neutralize the toxin. The ASO titres quantifies the concentration of ASO antibodies in the bloodstream, signaling the body’s immune response to a recent or ongoing streptococcal infection.
An abnormal or positive test result means you recently had a streptococcal infection, even if you had no symptoms. Additionally, monitoring ASO levels over time can help assess the efficacy of the treatment and detect any potential complication, such as rheumatic fever or acute glomerulonephritis which may arise as a result of streptococcal infection. Therefore, the Anti Streptolysin O Titer test plays an important role in diagnosing and managing streptococcal infections and associated conditions.





FAQs related to Anti Streptolysin O Titer
- Strep Antistreptolysin O Titer (Blood) [Internet]. Rochester, NY: University of Rochester Medical Center; [Accessed 11 Jun. 2024]. Available from:
- Anti-Streptolysin O [Internet]. ScienceDirect; [Accessed 11 Jun. 2024]. Available from:
- Brimo Alsaman MZ, Shashaa MN, Alkarrash MS, Kitaz MN, Zazo A, Alhamid A, Zazo R, Haj Kadour S. Normal values of antistreptolysin O for adults ages 30 to 70 in Syria: A cross sectional study. Ann Med Surg (Lond). 2021 Nov 5;71:103015. [Accessed 11 Jun. 2024]. Available from:
- Kotby AA, Habeeb NM, Ezz El Elarab S. Antistreptolysin O titer in health and disease: levels and significance. Pediatr Rep. 2012 Jan 2;4(1):e8. [Accessed 11 Jun. 2024]. Available from:
Other tests
- PT INR (Prothrombin Time with INR)
- HIV 1 and 2 Antibody, Rapid Screening Test
- Viral Marker Screening (HIV, HBsAg, Anti-HCV)
- Total IgE
- Rheumatoid Factor - Quantitative
- STD Panel (Sexually Transmitted Diseases Panel)
- HIV Combo (Antigen And Antibody) Test
- Anti-CCP Antibody
- Lipid Profile, Non Fasting
- Anti-Nuclear Antibody (ANA) by IFA - End Point Titer
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- PPBS (Postprandial Blood Sugar)
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid -19 test- RT PCR
- LFT (Liver Function Test)
- KFT (Kidney Function Test)
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid, Serum
- Vitamin B12
- CRP (C-Reactive Protein), Quantitative
- Urine C/S (Urine Culture and Sensitivity)
- Serum Electrolytes
- Serum Calcium
- Serum Creatinine
- Diabetes Screening (HbA1C & Fasting Sugar)
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hb (Hemoglobin)
- Complete Hemogram (CBC & ESR)























