Hypothyroidism / Hashimato's Disease Panel in New Delhi
Understanding Hypothyroidism / Hashimato's Disease Panel in New Delhi
What is Hypothyroidism / Hashimato's Disease Panel in New Delhi?
Hypothyroidism / Hashimato's Disease Panel is done to assess thyroid function in those suspected of thyroid disease including hypothyroidism or Hashimoto’s thyroiditis. Hashimoto's disease is an autoimmune disorder that can cause hypothyroidism, or underactive thyroid, rarely even present with hyperthyroidism (or hyperactive thyroid). This panel measures the levels of FT4, TSH, and Anti-TPO in the blood.
In autoimmune thyroid disorders, such as Hashimoto's thyroiditis, the immune system produces antibodies against thyroid peroxidase (TPO), an enzyme found in the thyroid gland. An Anti-TPO Antibody(Anti-Thyroid Peroxidase Antibody) test detects and measures these antibodies. TSH is a hormone secreted by the pituitary which controls the secretion of thyroid hormones. FT4 is free-T4, or the active part of T4 hormone. The panel also measures these hormones to help regulate therapy.
What does Hypothyroidism / Hashimato's Disease Panel measure?
Contains 3 testsTSH (Thyroid Stimulating Hormone) Ultrasensitive
A TSH (Thyroid Stimulating Hormone) Ultrasensitive test measures the levels of TSH hormone in the blood. TSH is produced by the pituitary gland located in the brain. Its function is to stimulate and regulate the functioning of the thyroid gland. It signals the thyroid gland to increase or decrease the production of thyroid hormones T3 and T4 (essential for regulating our body’s metabolism, temperature, heart rate, and growth) when their levels are low or high, respectively. Therefore, when the levels of T3 & T4 decrease, the pituitary gland is stimulated to release TSH. This high TSH level, in turn, stimulates the thyroid gland to release more thyroid hormones (T3 & T4); the vice-versa happens when the levels of thyroid hormones increase.
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Anti-TPO Antibody(Anti-Thyroid Peroxidase Antibody)
In autoimmune thyroid disorders, such as Hashimoto's thyroiditis and Graves’ disease, the immune system produces antibodies against thyroid peroxidase (TPO), an enzyme found in the thyroid gland. An Anti-TPO Antibody(Anti-Thyroid Peroxidase Antibody) test detects and measures the levels of these anti-thyroid peroxidase (anti-TPO) antibodies in your blood.
TPO is found in the cells of the thyroid follicle and helps produce the thyroid hormones thyroxine (T4) or triiodothyronine (T3). The presence of anti-TPO antibodies indicates autoimmune activity against the thyroid gland. These antibodies contribute to inflammation and damage to thyroid cells, thus leading to thyroid dysfunction.
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Thyroxine - Free
A Thyroxine - Free test measures the free form of thyroxine (T4) hormone made by the thyroid gland. T4 hormone exists in the blood in two forms: bound (attached to proteins) and free (not attached to proteins). Most of the T4 hormone circulating in the blood is bound to proteins and only a small part is free. A delicate balance of bound and free T4 should be maintained to ensure the proper functioning of the body.
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