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Zydibate-Plus Lotion 1
Zydibate-Plus Lotion 2
Genuine
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Zydibate-Plus Lotion is a medicine used to treat inflammatory skin conditions such as dermatitis, eczema, and psoriasis. It helps reduce redness, swelling, itching, and irritation in the affected areas.

Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 01 Nov 2026 | 01:01 AM (IST)
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MRP ₹194.5
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50 ml Lotion
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Product expires after Dec, 2027

Expiry date may vary by batch. All batches have a 3-month shelf life from the date of dispatch.

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The content is shown in English
Zydibate-Plus Lotion 1
Zydibate-Plus Lotion 2

Product introduction

Use Zydibate-Plus Lotion exactly as prescribed by your doctor. Apply it only to the affected areas of the skin and follow the recommended frequency and duration of treatment. Continue using it for the prescribed period, even if your symptoms improve earlier. Do not use more than the recommended amount or extend the treatment without consulting your doctor.


There is limited information available regarding the common side effects of Zydibate-Plus Lotion. However, some people may experience mild burning, stinging, itching, redness, or irritation at the application site. These effects are usually temporary and may improve as the skin adjusts to the medicine. However, if the irritation persists or worsens, stop using it and consult your doctor.


Before using Zydibate-Plus Lotion, inform your doctor if you have any skin infection, broken skin, or a history of allergy to betamethasone, zinc sulfate, or other ingredients in the formulation. Avoid applying it to the face, groin, underarms, or large areas of skin unless specifically advised. Do not cover the treated area with airtight dressings, as this may increase corticosteroid absorption and the risk of side effects. Pregnant and breastfeeding women should consult their doctor before using this medicine.

Benefits of Zydibate-Plus Lotion

Treatment of Dermatitis
Zydibate-Plus Lotion helps manage the symptoms of dermatitis such as dry, itchy, swollen, red, and painful skin with a burning sensation. It has a soothing effect on the skin and gives relief from itching. Zydibate-Plus Lotion also has antiseptic properties that help prevent infection in the affected area.
Treatment of Psoriasis
Psoriasis is a chronic skin condition that causes thick, scaly patches accompanied by redness, itching, and inflammation. Zydibate-Plus Lotion helps reduce inflammation and relieve symptoms such as redness, itching, and irritation. It may also help reduce scaling and improve the appearance of affected skin.
Treatment of Eczema
Eczema is a skin condition that causes redness, itching, dryness, and inflammation. Zydibate-Plus Lotion helps reduce inflammation and provides relief from symptoms such as itching, redness, and swelling. It soothes irritated skin and reduces the discomfort associated with eczema.

Side effects of Zydibate-Plus Lotion

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Zydibate-Plus
  • Limited data available

How to use Zydibate-Plus Lotion

This medicine is for external use only. Use this medicine in the dose and duration as advised by your doctor. Shake it well and apply to the area evenly.

How Zydibate-Plus Lotion works

Zydibate-Plus Lotion is a combination of two medicines: Betamethasone and Zinc Sulfate. Betamethasone is a steroid that blocks the production of certain chemical messengers (prostaglandins) that make the skin red, swollen, and itchy. Zinc Sulfate works as an astringent and antiseptic on the skin.

All substitutes for Zydibate-Plus Lotion

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

  • It may cause minor burning, stinging, or irritation when applied. Inform your doctor if this does not go away.
  • Do not cover the area being treated with airtight dressings such as bandages unless directed by a doctor, as this may increase the risk of side effects.
  • Do not apply it to broken or infected areas of skin unless instructed by your doctor. 
  • Avoid contact with your eyes, nose or mouth. Rinse it off with water if you accidentally get it in these areas.
  • Do not use this medicine more often or for longer than advised by your doctor. Consult your doctor if your skin condition has not improved after two weeks of treatment.

Safety advice

Alcohol

Alcohol

No interaction found/established
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Information regarding the use of Zydibate-Plus Lotion during pregnancy is not available. Please consult your doctor.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Zydibate-Plus Lotion during breastfeeding is not available. Please consult your doctor.
Driving

Driving

No interaction found/established
Kidney

Kidney

No interaction found/established
Liver

Liver

No interaction found/established

Frequently asked questions

Zydibate-Plus Lotion should be used as advised by the doctor or as per the instructions on the label of the medicine. The dose would depend on the condition for which it is prescribed. Wash your hands after using Zydibate-Plus Lotion unless it is used for treating a condition of the hands. Avoid any contact with the eyes.
No, do not stop using Zydibate-Plus Lotion and complete the full course of treatment even if you feel better. Your symptoms may improve before the underlying disease is completely cured.
Do not use Zydibate-Plus Lotion for longer periods of time than advised. Avoid covering the treated area, as this will increase absorption and increase the risk of side effects. Do not share your medicine with other people even if their condition appears to be the same.
Keep this medicine in the packet or the container it came in. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Keep it away from pets and children.

Fact Box

Habit Forming

No

Therapeutic Class

DERMA

References

  1. Chrousos GP. Adrenocorticosteroids & Adrenocortical Antagonists. In: Katzung BG, Masters SB, Trevor AJ (Editors). Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 681-697.
  2. Schimmer BP, Parker KL. Adrenocorticotropic Hormone, Adrenal Steroids, and the Adrenal Cortex. In: Brunton LL, Chabner BA, Knollmann BC (Editors). Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 13th ed. New York, New York: McGraw-Hill Medical; 2018. pp. 845-861.
  3. Betamethasone dipropionate [Prescribing Information]. Cramlington, UK: Organon Pharma (UK) Limited; 2025. [Accessed 30 Oct. 2026] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Zydillac Dermaceuticals
Address: AO/A-42 INDRAPURI Ghaziabad-201102

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Zydibate-Plus Lotion. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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