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Zrepag MF 2mg/500mg Tablet

Repaglinide (2mg)+ Metformin (500mg)
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Zrepag MF 2mg/500mg Tablet belongs to a category of medicines known as anti-diabetic drugs. It is a combination of two medicines used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 13 Jul 2026 | 01:05 AM (IST)
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Zrepag MF 2mg/500mg Tablet image
Zrepag MF 2mg/500mg Tablet image

Product introduction

Zrepag MF 2mg/500mg Tablet should be taken with food. Take it regularly at the same time each day to get the most benefit. Your doctor will decide what dose is best for you and this may change from time to time according to how it is working according to your blood sugar levels.

Keep taking this medicine, even if you feel well or your blood sugar levels are controlled. If you stop it without consulting your doctor, your blood sugar levels could rise and put you at risk of kidney damage, blindness, nerve problems and loss of limbs. Remember that it is only part of a treatment program that should also include a healthy diet, regular exercise, and weight reduction as advised by your doctor. Your lifestyle plays a big part in controlling diabetes.

The most common side effect of Zrepag MF 2mg/500mg Tablet is low blood glucose levels (hypoglycemia). Make sure you recognize the signs of having low blood glucose levels, such as sweating, dizziness, headache, and shaking and know how to deal with it. To prevent this, it's important to have regular meals and always carry a fast-acting source of glucose such as sugary food or fruit juice with you. Drinking alcohol can also increase your risk of low blood sugar levels and should be avoided. Other side effects that may be seen in taking this medicine include taste changes, nausea, diarrhea, stomach pain, headache, and upper respiratory tract infection. Some people may find that they put on weight with this medicine.

You should not take it if you have type 1 diabetes mellitus, if you have diabetic ketoacidosis (high levels of acid in your blood), or if you have severe kidney or liver disease. Before taking this medicine, tell your doctor if you have ever had heart disease. It may not be suitable. Pregnant or breastfeeding women should also consult their doctor before taking it. Your blood sugar levels should be checked regularly and your doctor may also advise blood tests to monitor your blood cell counts and liver function.

Uses of Zrepag MF Tablet

Benefits of Zrepag MF Tablet

Treatment of Type 2 diabetes mellitus
Type 2 diabetes is a long-term condition where the body either does not produce enough insulin or cannot use it effectively, leading to high blood sugar levels. If uncontrolled, it can damage the eyes, kidneys, nerves, and heart. Zrepag MF 2mg/500mg Tablet stimulates the pancreas to release more insulin after meals, helping to control sudden spikes in blood sugar. It reduces the amount of sugar produced by the liver and improves the body’s response to insulin. Overall, this medicine helps maintain steady blood sugar levels throughout the day and reduces the risk of long-term diabetes-related complications.

Side effects of Zrepag MF Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Zrepag MF
  • Sweating
  • Weight gain
  • Diarrhea
  • Headache
  • Nausea
  • Hypoglycemia (low blood glucose level)
  • Upper respiratory tract infection
  • Abdominal pain
  • Flatulence

How to use Zrepag MF Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zrepag MF 2mg/500mg Tablet should be taken with or after food.

How Zrepag MF Tablet works

Repaglinide and metformin. Repaglinide is a meglitinide analogue which increases the amount of insulin released by the pancreas. This prevents blood glucose from rising very high after meals. Metformin is a biguanide which decreases the production and absorption of sugar in your body and allows better use of existing insulin. Together, they provide better control of blood sugar.

All substitutes for Zrepag MF 2mg/500mg Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

  • It is fast-acting and reaches full effect within an hour.
  • You should continue to exercise regularly, eat a healthy diet, and take your other diabetes medicines (if prescribed) along with Zrepag MF 2mg/500mg Tablet.
  • It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal. 
  • Always carry some sugary food or fruit juice with you in case you experience hypoglycemia symptoms such as cold sweats, cool pale skin, tremor, and anxious feeling.
  • Monitor your blood sugar regularly while taking this medicine.
  • It is fast-acting and reaches full effect within an hour.
  • You should continue to exercise regularly, eat a healthy diet, and take your other diabetes medicines (if prescribed) along with Zrepag MF 2mg/500mg Tablet.
  • It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal. 
  • Always carry some sugary food or fruit juice with you in case you experience hypoglycemia symptoms such as cold sweats, cool pale skin, tremor, and anxious feeling.
  • Monitor your blood sugar regularly while taking this medicine.

Safety advice

Alcohol

Alcohol

UNSAFE
It is unsafe to consume alcohol with Zrepag MF 2mg/500mg Tablet
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Zrepag MF 2mg/500mg Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

UNSAFE
Zrepag MF 2mg/500mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving

Driving

CAUTION
Zrepag MF 2mg/500mg Tablet may affect your driving ability if your blood sugar becomes too low or too high. Monitor your blood glucose and avoid driving if affected.
Kidney

Kidney

UNSAFE
Zrepag MF 2mg/500mg Tablet is unsafe to use in patients with kidney disease and should be avoided.
Liver

Liver

UNSAFE
Zrepag MF 2mg/500mg Tablet is unsafe to use in patients with liver disease and should be avoided.
All

Frequently asked questions

Zrepag MF 2mg/500mg Tablet is prescribed to help control blood sugar levels in adults with type 2 diabetes, especially when diet, exercise, and single-medicine therapy are not enough.
People should not take Zrepag MF 2mg/500mg Tablet if they have severe kidney or liver problems. Metabolic acidosis (a condition where there is too much acid in the body fluids), diabetic ketoacidosis (a serious, life-threatening complication of diabetes where the body does not produce enough insulin, leading to a buildup of acids (ketones) in the blood), or are allergic to any ingredients present in this medicine.
Yes, Zrepag MF 2mg/500mg Tablet can cause low blood sugar, especially if you skip meals, exercise heavily, or drink alcohol. Know symptoms like sweating, shakiness, and confusion, and treat them promptly.
Serious side effects of Zrepag MF 2mg/500mg Tablet include lactic acidosis (with symptoms like weakness, trouble breathing, stomach pain), severe allergic reactions, and abnormal liver tests. Seek medical help immediately if these happen.
While on Zrepag MF 2mg/500mg Tablet treatment, regular blood tests may be needed to monitor your blood sugar, kidney, and liver function, as advised by your doctor.
You should contact your doctor if you notice symptoms of low blood sugar, persistent nausea or vomiting, muscle pain, dark urine, or unexpected illnesses during Zrepag MF 2mg/500mg Tablet treatment.

Fact Box

Habit Forming

No

Therapeutic Class

ANTI DIABETIC
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100% genuine products
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No contact delivery
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Daylon Healthcare
Address: 715, Gold Crest business center, L.T road, Borivali-W, Mumbai 400092

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Zrepag MF 2mg/500mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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