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MD (Pharmacology), MBBS
Last updated:
18 Feb 2020 | 05:25 PM (IST)
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Zophost 10mg Tablet


Overview

Introduction

Zophost 10mg Tablet is used to treat or prevent weakening of the bones (osteoporosis) caused by menopause or use of steroids. Using this medicine can reduce your risk of breaking bones.

Zophost 10mg Tablet is best taken without food. You should take it regularly at evenly spaced intervals as per the schedule prescribed by your doctor. Taking it at the same time every day will help you to remember to take it. Do not stop taking it until you have finished, even when you feel better. It may take several days to get the full benefit of this drug. Zophost 10mg Tablet is only part of a programme of treatment that may also include changes to your diet and taking calcium and vitamin supplements.

The most common side effects include headache, musculoskeletal (bone, muscle or joint) pain, indigestion, heartburn and diarrhea. These are usually mild and will disappear after a short time. If they do not go away, tell your doctor. Zophost 10mg Tablet can cause serious kidney problems, especially if you are dehydrated, if you take diuretic medicine (water pills), or if you already have kidney disease. It can also cause low levels of calcium in the blood and pain in the mouth or jaw. These are serious side effects and need urgent medical attention. Tell your doctor straight away.

You should not be given this medicine if you are breastfeeding. Before taking it, tell your doctor if you have kidney problems or low calcium levels. Also let your doctor know what other drugs you are taking. Some of them may affect or be affected by, this medicine, especially medicines used to treat severe infections and osteoporosis. You may need frequent medical tests to check your kidney function and mineral levels. Avoid smoking or try to quit as smoking can reduce your bone mineral density, making fractures more likely. Drinking large amounts of alcohol can also cause bone loss and should be avoided.

Uses of Zophost Tablet

Side effects of Zophost Tablet

Common
  • Diarrhea
  • Headache
  • Heartburn
  • Musculoskeletal (bone, muscle or joint) pain

How to cope with side effects?

The occurrence of side effects varies from person to person. The following are a few ways of dealing with some of the common side effects. However, consult your doctor if these persist.

  • Coping with Diarrhea
    Keep up your intake of fluids and electrolytes (sugars and salts) to avoid getting dehydrated. Eat less fiber (avoid raw fruits, fruit juice and vegetables). Talk to your doctor about possible medication to manage diarrhea. Ask about reducing the dosage of your drug or other suitable treatments.
  • Coping with Headache
    Make sure you rest and drink plenty of fluids. Rest in a quiet, dimly lit room. Do not sleep more than you normally would. Do not strain your eyes (for example by looking at a screen). Do not drink alcohol. Headaches are usually temporary and usually go away with time. But, if they last longer or get worse, ask your doctor to recommend a painkiller.
  • Coping with Heartburn
    Avoid foods that irritate the stomach such as alcohol, carbonated soft drinks, citrus, coffee, fatty foods or tomatoes. Eat or drink slowly. Eat smaller, more frequent meals. The reason being, large meals fill the stomach and put pressure, causing reflux. Quit smoking if you smoke, lose weight if you are overweight and avoid tight waistbands. Ask your doctor about medicines to treat this condition such as antacids. Do not lie down immediately after eating and wait for at least three hours before lying down after a meal. Raise the head of your bed. Talk to your doctor if your condition does not improve, they may be able to reduce the dosage or switch you to another medicine.
  • Coping with Musculoskeletal (bone, muscle or joint) pain
    Tell your doctor straight away because sometimes the muscle pain may be a sign of something more serious. A lower dosage or a different medication might be needed. Try to relax the cramping muscle by stretching it and holding the stretch. You might massage the muscle or apply a heat pad to the area after stretching. Avoid exercising too much. Stay well-hydrated. Do not take over-the-counter pain relievers unless the doctor prescribes it. Your doctor may also suggest taking supplements, such as calcium, magnesium oxide or potassium oxide depending on your needs.

How to use Zophost Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zophost 10mg Tablet is to be taken empty stomach.

How Zophost Tablet works

Zophost 10mg Tablet is a bisphosphonate. It works by suppressing the activity of osteoclasts, cells that cause destruction of bone. This strengthens the bones and minimizes the risk of fractures.

Safety Advice

Alcohol
SAFE
Consuming alcohol with Zophost 10mg Tablet does not cause any harmful side effects.
Pregnancy
CONSULT YOUR DOCTOR
Zophost 10mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breastfeeding
SAFE IF PRESCRIBED
Zophost 10mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
If you are taking Zophost 10mg Tablet during breastfeeding, monitor baby's blood calcium levels during the first two months.
Driving
UNSAFE
Zophost 10mg Tablet may cause side effects which could affect your ability to drive.
Zophost 10mg Tablet is not expected to have any effects but in rare cases, it may cause dizziness, severe muscle, joint and bone pain and eye pain or inflammation. This may affect your ability to drive.
Kidney
CAUTION
Zophost 10mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Zophost 10mg Tablet may be needed. Please consult your doctor.
Dose adjustment is not recommended in patients with mild to moderate kidney disease.
Liver
SAFE IF PRESCRIBED
Zophost 10mg Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Zophost 10mg Tablet may not be needed in these patients. Please consult your doctor.

What if you forget to take Zophost Tablet?

If you miss a dose of Zophost 10mg Tablet, skip it and continue with your normal schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Zophost 10mg Tablet
₹4.0/Tablet
Alenost 10mg Tablet
Macleods Pharmaceuticals Pvt Ltd
₹4.9/Tablet
22% costlier
Poronil 10mg Tablet
Finecure Pharmaceuticals Ltd.
₹4.95/Tablet
24% costlier
₹5.48/Tablet
37% costlier
Alenfos 10mg Tablet
Marc Laboratories Pvt Ltd
₹6/Tablet
50% costlier
Restofos 10mg Tablet
Sun Pharmaceutical Industries Ltd
₹6.21/Tablet
55% costlier

Quick Tips

  • Your doctor has prescribed Zophost 10mg Tablet to make your bones stronger and lower the risk of fractures.
  • Take it in the morning at least 30 minutes before eating or drinking anything.
  • Maintain an upright posture for 30 minutes after taking the medication so the medicine does not irritate your food pipe.
  • It may cause the amount of calcium in your blood to fall. Take calcium-rich food in your diet and have regular blood tests to monitor the level of calcium in your blood.
  • It is important to look after your mouth and teeth while you are taking this medicine. Have regular dental check-ups and inform your dentist about taking Zophost 10mg Tablet.

Interaction with Drugs

Taking Zophost with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Mikasun, Vizocin, Amricin
SERIOUS
Brand(s): Ciprix, Capreo, Capreotec
SERIOUS
Brand(s): Begenta, Indogenta, Spagen
SERIOUS
Brand(s): Neokanyn
SERIOUS

Patient Concerns

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Side effect of osteoporosis tab
Dr. Akshat Goel
Orthopaedics
Please mention the contents of the tablet
What is a quick solution for running nose , watery eyes , sneezing
Dr. Pushkar Mani
Physician
ALERID 10MG TABLET twice daily for 3 days
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Do you have any questions related to Zophost 10mg Tablet ?

FAQs

Q. How to take Zophost?

It should be taken in the morning after getting up on an empty stomach with a full glass of water. Do not lie down and stay fully upright for at least 30 minutes after swallowing the medicine. Avoid taking any food or medication for next 30 mins after taking this medicine. Consult your doctor before you start this medication and follow the instruction as given.

Q. Why can you not lie down after taking Zophost?

It is advised not to lie down after taking Zophost because the medication might come back up into the esophagus (food pipe). This can damage the esophagus. Staying upright will help the medicine to settle down quickly in your stomach and prevent from side effects like heartburn and pain.

Q. Does Zophost cause hair loss?

Yes, Zophost can cause hair loss, but this is not a common side effect. If you experience hair loss while taking this medication immediately report to your doctor and follow the advice given.

Q. Can Zophost be used in pregnant women?

Zophost should be avoided during pregnancy. There is a lack of data regarding the use of Zophost in pregnant women. You should consult your doctor if you are pregnant or planning to get pregnant before taking this medication.

Q. Does Zophost cause cancer/ hair loss/ make you tired/ increase in blood pressure?

Zophost has a side effect of causing hair loss and tiredness. However, it is not known to cause cancer or increase in blood pressure. Consult your doctor if you experience such side effects.

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Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Alendronic acid. North Harrow, Middlesex: Accord Healthcare Limited; 2008 [revised 02 Mar. 2017]. [Accessed 02 Apr. 2019] (online) Available from:External Link
  2. Alendronate sodium. North Harrow, Middlesex: Accord Healthcare Limited; 2008 [revised 2 Mar. 2017]. [Accessed 28 Jan. 2019] (online) Available from:External Link
  3. Alendronic acid. Whitehouse, New Jersey: Merck Sharp & Dohme Corp.; 1995 [revised Mar. 2016]. [Accessed 02 Apr. 2019] (online) Available from:External Link
  4. Central Drugs Standard Control Organisation (CDSCO). [Accessed 02 Apr. 2019] (online) Available from:External Link
Manufacturer/Marketer Address
KHANDELWAL LABORATORIES PVT. LTD, 79/87 D.LADPATH, MUMBAI 400 033, INDIA
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