Author Details
Written By
Reviewed By
MD (Pharmacology), MBBS
Last updated
05 Aug 2022 | 04:52 PM (IST)

We provide you with authentic, trustworthy and revelant information

Want to know more

Have issue with the content?

Report Problem

Zolsoma 5 Tablet

Prescription Required
Manufacturer/ Marketer
Store below 30°C

Product introduction

Zolsoma 5 Tablet is a combination medicine used in the treatment of insomnia. It helps to synchronize the body’s biological day-night rhythm. It resolves trouble falling asleep and ensures sound sleep.

Zolsoma 5 Tablet is to be taken on an empty stomach, preferably just before bedtime. However, it is advised to take it at a fixed time each day to maintain a consistent level of medicine in the blood. You should never skip any doses and finish the full course of treatment even if you feel better. This medicine should not be stopped suddenly without talking to your doctor.

Some common side effects of this medicine include nausea, diarrhea, and headache. It even causes dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. It is important to note that this medicine should not be used for daily naps.

Consult your doctor before taking this medicine if you are suffering from any liver or kidney problems. You should avoid smoking and alcohol while using this medicine. Pregnant and breastfeeding mothers should not use this medicine. However, if the need arises, please consult your doctor before using it.

Uses of Zolsoma Tablet

Benefits of Zolsoma Tablet

In Insomnia

Zolsoma 5 Tablet helps treat insomnia (difficulty falling or staying asleep) in people who have problems related to their sleeping habits. Insomnia may cause you to wake up earlier than usual and you may find it difficult to go back to sleep. It works by slowing down the abnormal activity of nerves in the brain to allow sleep. It also improves the sleep-wake cycle and restores it to normal. This helps you relax, feel calm and more energetic. It also helps you concentrate better and improves your quality of life.

Side effects of Zolsoma Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Zolsoma

  • Nausea
  • Diarrhea
  • Headache
  • Dizziness
  • Drowsiness

How to use Zolsoma Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zolsoma 5 Tablet is to be taken empty stomach.

How Zolsoma Tablet works

Zolsoma 5 Tablet is a combination of two medicines: Melatonin and Zolpidem which work on your brain to make you feel relaxed and sleepy. Melatonin is a natural hormone which regulates the sleep-wake cycle and helps fall asleep. Zolpidem is a sedative which works by slowing activity of the nerve cells in the brain and helps sleep for longer.

Safety advice

It is unsafe to consume alcohol with Zolsoma 5 Tablet.
Zolsoma 5 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
Zolsoma 5 Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Zolsoma 5 Tablet is safe as per American Association of Pregnancy.
Zolsoma 5 Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
There is limited information available on the use of Zolsoma 5 Tablet in patients with kidney disease. Please consult your doctor.
However, based on the limited information available it is advised that Zolsoma 5 Tablet should be used with caution in patients with kidney disease.
Zolsoma 5 Tablet should be used with caution in patients with liver disease. Dose adjustment of Zolsoma 5 Tablet may be needed. Please consult your doctor.
Zolsoma 5 Tablet is generally started at a low dose in patients with mild to moderate liver disease and is not recommended in patients with severe liver disease.

What if you forget to take Zolsoma Tablet?

If you miss a dose of Zolsoma 5 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Zolsoma 5 Tablet
Lexa-H Tablet
Seagull Pharmaceutical Pvt Ltd
22% cheaper
Somnisure M 3mg/5mg Tablet
Matteo Healthcare Pvt Ltd
18% cheaper
Zolcalm 5mg Tablet
Linux Laboratories
11% cheaper

Quick tips

  • Zolsoma 5 Tablet helps promote sleep in people who have difficulty sleeping.
  • Take the tablet before going to bed. This will help the medicine to work later in the night.
  • Do not drink alcohol while you are taking Zolsoma 5 Tablet because it will reduce its effectiveness in helping you to sleep.
  • Apart from taking this medicine, incorporate these tips to prevent insomnia: 
    1. Try to reduce the amount of caffeine you drink, especially in the afternoon and evening. 
    2. Avoid eating heavy meals before bedtime. 
    3. Exercise early in the day, rather than in the evening.
    4. Reduce screen time before going to bed.
    5. Keep regular sleeping hours.
    6. Create a sleeping environment by switching off lights and having an ambient room temperature.
    7. If you are unable to sleep, do not lie down on the bed worrying about it. Get up and do something you find relaxing until you feel sleepy again, then go back to bed.

Fact Box

Habit Forming
Therapeutic Class

Patient concerns

Am addicted with alprazolam , Zolsoma How can I quet please
Dr. Jyoti Kapoor Madan
Addiction problems require understanding of patterns of abuse, withdrawal symptoms , underlying psychopathology followed by detoxification and rehabilitation plan. For further understanding of the issue, you may go through the following link-
I m already taken 10 no of Zolsoma(zolpdam & melatonin acid
Dr. Jyoti Kapoor Madan
Sleep problems are often caused by underlying physical and/ or psychological cause. This requires examination of the patient so that proper treatment can be initiated. Often stress/ anxiety/ depression or mood disorder needs to be dealt with and sleeping pills are not adequate treatment. Please go through the link below for further understanding-

User feedback

Related ayurvedic ingredients

Want to share the information?


Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.


  1. Melatonin. Barcarena, Portugal: Iberfar - Indústria Farmacêutica S.A; 2018. [Accessed 23 Apr. 2019] (online) Available from:External Link
  2. Zolpidem. [Accessed 23 Apr. 2019] (online) Available from:External Link
  3. Melatoin. Dublin 2, Republic of Ireland: Flynn Pharma Ltd.; 2007 [revised 31 May 2018]. [Accessed 23 Apr. 2019] (online) Available from:External Link
  4. Zolpidem Tartrate. Guildford, Surrey: Zentiva; 2002 [revised 7 Dec. 2018]. [Accessed 23 Apr. 2019] (online) Available from:External Link

Manufacturer/Marketer address

4F10, Ballad Estates, Tarnaka, Hyderabad - 500017, TS, India.
Country of origin: India
We do not facilitate sale of this product at present


Orders Delivered
Get the link to download App

All products displayed on Tata 1mg are procured from verified and licensed pharmacies. All labs listed on the platform are accredited


Tata 1mg uses Secure Sockets Layer (SSL) 128-bit encryption and is Payment Card Industry Data Security Standard (PCI DSS) compliant


Find affordable medicine substitutes, save up to 50% on health products, up to 80% off on lab tests and free doctor consultations.

LegitScript approved
India's only LegitScript and ISO/ IEC 27001 certified online healthcare platform

Know more about Tata 1mgdownArrow

Access medical and health information

Tata 1mg provides you with medical information which is curated, written and verified by experts, accurate and trustworthy. Our experts create high-quality content about medicines, diseases, lab investigations, Over-The-Counter (OTC) health products, Ayurvedic herbs/ingredients, and alternative remedies.

Order medicines online

Get free medicine home delivery in over 1800 cities across India. You can also order Ayurvedic, Homeopathic and other Over-The-Counter (OTC) health products. Your safety is our top priority. All products displayed on Tata 1mg are procured from verified and licensed pharmacies.

Book lab tests

Book any lab tests and preventive health packages from certified labs and get tested from the comfort of your home. Enjoy free home sample collection, view reports online and consult a doctor online for free.

Consult a doctor online

Got a health query? Consult doctors online from the comfort of your home for free. Chat privately with our registered medical specialists to connect directly with verified doctors. Your privacy is guaranteed.