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Zayo 50 Tablet

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Product introduction

Zayo 50 Tablet is a combination of two medicines used to treat heart failure. It reduces the risk of hospitalization and death in patients with long-lasting (chronic) heart failure. It is generally given along with other heart failure medications.

Zayo 50 Tablet may be taken with or without food. Take it at the same time each day for maximum benefits. The dose, and how often you take it, will be decided by your doctor and may change depending on how well you respond to the medicine. Keep taking the tablets regularly, as they have been prescribed, and try not to miss doses to get the most benefit. Do not stop taking them, even if you are feeling well. The medicine prevents future complications.

Common side effects of this medicine include angioedema, low blood pressure (hypotension), impaired renal function, and high potassium level in blood (hyperkalemia). To reduce the risk of dizziness that may caused by low blood pressure, try getting up slowly from a sitting or lying position. If these or other side effects are severe or do not go away, tell your doctor.

Before taking this medicine, tell your doctor if you are taking any other medicines for blood pressure or heart conditions or if you have kidney or liver disease. Also let your doctor know all other medications you are using as they may affect, or be affected by, this medicine. This medicine should not be taken during pregnancy and is not recommended while breastfeeding. While on treatment with this medicine, your doctor may advice regular monitoring of blood pressure and regular kidney function.


Uses of Zayo Tablet

Benefits of Zayo Tablet

In Treatment of Heart failure

Heart failure means your heart is weak and cannot pump enough blood to your lungs and the rest of your body. The most common symptoms are breathlessness, tiredness, and swelling in your legs, ankles, abdomen, and other parts of your body. Zayo 50 Tablet is a combination of two medicine namely valsartan and sacubitril. Both of these medicines work in different ways to lower blood pressure. This makes it easier for your heart to pump blood around your body and is therefore an effective treatment for heart failure.

This medicine will help relieve your symptoms, making you feel better and more energetic. You should make appropriate lifestyle changes (such as eating healthily and keeping active) to help this medicine be effective. Take it regularly and keep taking it even if you feel better.

Side effects of Zayo Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Zayo

  • Hypotension (low blood pressure)
  • Increased potassium level in blood

How to use Zayo Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zayo 50 Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Zayo Tablet works

Zayo 50 Tablet is a combination of two medicines: Sacubitril and Valsartan which belong to a class of angiotensin receptor neprilysin inhibitor (ARNI). This combination treats heart failure by relaxing the blood vessels and making it easier for your heart to pump blood throughout your body. In addition, it also helps your body retain less water.

Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Zayo 50 Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Zayo 50 Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Zayo 50 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Zayo 50 Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Zayo 50 Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Zayo 50 Tablet may be needed. Please consult your doctor.
Regular blood pressure monitoring is recommended. No dose adjustment is needed in patients with mild to moderate kidney disease.
Liver
CAUTION
Zayo 50 Tablet should be used with caution in patients with liver disease. Dose adjustment of Zayo 50 Tablet may be needed. Please consult your doctor.
No dose adjustment is recommended in patients with mild to moderate liver disease.

What if you forget to take Zayo Tablet?

If you miss a dose of Zayo 50 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Zayo 50 Tablet
₹33.93/Tablet
Vymada 50mg Tablet
Novartis India Ltd
₹43.29/tablet
28% costlier
CIDMUS 50mg Tablet
Dr Reddy's Laboratories Ltd
₹29.79/tablet
12% cheaper
Sacurise 50 Tablet
Sun Pharmaceutical Industries Ltd
₹14.57/tablet
57% cheaper
Azmarda 50mg Tablet
J B Chemicals and Pharmaceuticals Ltd
₹40.43/tablet
19% costlier
Neptaz 50mg Tablet
Mankind Pharma Ltd
₹21.07/tablet
38% cheaper

Quick tips

  • You have been prescribed Zayo 50 Tablet for the treatment of of long-lasting (chronic) heart failure.
  • You should continue to stay active (light walking, stretching) and eat a healthy, low sodium diet along with taking this medication.
  • To reduce the chances of feeling dizzy, rise slowly if you have been sitting or lying down.
  • It may cause the level of potassium in your blood to go up. Avoid taking potassium supplements and potassium-rich foods such as banana and broccoli.
  • Inform your doctor if you have a history of liver or kidney diseases.
  • Do not take Zayo 50 Tablet if you are pregnant or breastfeeding.

Fact Box

Habit Forming
No
Therapeutic Class
CARDIAC

Patient concerns

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What is BNP test? Pls explain. What is BNP ASSAY?My result is133.0 explain
Dr. Manju Singh
Homeopathy
BNP levels below 100 pg/mL indicate no heart failure. BNP levels of 100-300 pg/mL suggest heart failure is present. BNP levels above 300 pg/mL indicate mild heart failure. BNP levels above 600 pg/mL indicate moderate heart failure.The level of BNP in the blood increases when heart failure symptoms worsen, and decreases when the heart failure condition is stable
Myself is high B.P patients .There is some swelling in the face today . what is going on?
Dr. Pushkar Mani
Physician
Kidney damage or heart failure
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User feedback


FAQs

Q. Who should avoid taking Zayo 50 Tablet?

Patients who are allergic to any of its components should avoid Zayo 50 Tablet. Also, those who are allergic to the use of ACE inhibitors or ARBs should avoid using this medicine. It should not be used along with other antihypertensive medicines like ACE inhibitors or ARBs. Do not take it for at least 36 hours before or after you take an ACE inhibitor medicine. If you are not sure, consult your doctor.

Q. What should I tell my doctor before taking Zayo 50 Tablet?

Tell your doctor about all of your medical conditions, including liver or kidney disease, history of facial swelling (angioedema). Inform him if you are pregnant or are breastfeeding. Also, let your doctor know about all medicines you are taking, especially potassium supplements or its medicine salt, painkillers, blood pressure or heart failure medicines (such as ACE inhibitor, ARBs or Aliskiren).

Q. Can I use Zayo 50 Tablet in pregnancy?

No, Zayo 50 Tablet should be avoided in pregnancy. Its use can cause injury or even endanger the life of the baby. If you become pregnant while using Zayo 50 Tablet, stop using it and contact your doctor immediately.

Q. How would I know if I have high potassium levels?

Your doctor will check your blood potassium levels periodically to detect high potassium levels (hyperkalemia). Make sure that you do not miss any scheduled appointments with the doctor.

Q. Who should avoid taking Zayo 50 Tablet?

Patients who are allergic to any of its components should avoid Zayo 50 Tablet. Also, those who are allergic to the use of ACE inhibitors or ARBs should avoid using this medicine. It should not be used along with other antihypertensive medicines like ACE inhibitors or ARBs. Do not take it for at least 36 hours before or after you take an ACE inhibitor medicine. If you are not sure, consult your doctor.

Q. What should I tell my doctor before taking Zayo 50 Tablet?

Tell your doctor about all of your medical conditions, including liver or kidney disease, history of facial swelling (angioedema). Inform him if you are pregnant or are breastfeeding. Also, let your doctor know about all medicines you are taking, especially potassium supplements or its medicine salt, painkillers, blood pressure or heart failure medicines (such as ACE inhibitor, ARBs or Aliskiren).

Q. Can I use Zayo 50 Tablet in pregnancy?

No, Zayo 50 Tablet should be avoided in pregnancy. Its use can cause injury or even endanger the life of the baby. If you become pregnant while using Zayo 50 Tablet, stop using it and contact your doctor immediately.

Q. How would I know if I have high potassium levels?

Your doctor will check your blood potassium levels periodically to detect high potassium levels (hyperkalemia). Make sure that you do not miss any scheduled appointments with the doctor.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Medscape. Sacubitril+Valsartan. [Accessed 24 Apr. 2019] (online) Available from:External Link
  2. Sacubitril+Valsartan. East Hanover, New Jersey: Novartis Pharmaceuticals Corporation; 2015 [revised Nov. 2018]. [Accessed 24 Apr. 2019] (online) Available from:External Link
  3. Sacubitril and Valsartan [Prescribing Information]. Telangana, India: MSN Laboratories Private Limited; 2023. [Accessed 28th Sept. 2023] (online) Available from: External Link
  4. Sacubitril and Valsartan [Product Monograph]. Dublin 4, Ireland: Novartis Europharm Limited.2020. [Accessed 28th Sept. 2023] (online) Available from: External Link

Marketer details

Name: Eris Lifesciences Ltd
Address: 8th Floor, Commerce House IV, Prahladnagar, Ahmedabad – 380015 Gujarat, India
Country of origin: India

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