Author Details
Written By
MMST, MBBS
Reviewed By
MD (Pharmacology), MBBS
Last updated:
18 Feb 2020 | 05:26 PM (IST)
Want to know more?
Read Our Editorial Policy
Have issue with the content?
Report Problem

Zavedos 5mg Capsule

Prescription Required
Manufacturer
SALT COMPOSITION

Overview

Introduction

Zavedos 5mg Capsule is used in the treatment of some kinds of blood cancer (leukemia). It may be also used to treat other conditions, as determined by the doctor. It is sometimes used with certain other medicines as part of combination chemotherapy.

Zavedos 5mg Capsule can be taken with or without food, but try to have it at the same time every day to get most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include vomiting, nausea, infection, hair loss, and fever. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels.

Before taking it, tell your doctor if have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Side effects of Zavedos Capsule

Common
  • Vomiting
  • Nausea
  • Infection
  • Hair loss
  • Fever
  • Increased liver enzymes
  • Peripheral neuropathy (tingling and numbness of feet and hand)
  • Stomatitis (Inflammation of the mouth)
  • Bleeding
  • Myelosuppression
  • Seizure

How to use Zavedos Capsule

Take this medicine in the dose and duration as advised by your doctor. Do not chew, crush or break it. Zavedos 5mg Capsule may be taken with or without food, but it is better to take it at a fixed time.

How Zavedos Capsule works

Zavedos 5mg Capsule is an anti-cancer medication. It works by suppressing the activity of an enzyme (topoisomerase II) involved in DNA multiplication of the cancer cells. It also forms harmful chemicals (free radicals) which cause DNA damage. This slows the growth of cancer cells and eventually kills them.

Safety Advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Zavedos 5mg Capsule. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Zavedos 5mg Capsule is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breastfeeding
UNSAFE
Zavedos 5mg Capsule is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
UNSAFE
Zavedos 5mg Capsule may cause side effects which could affect your ability to drive.
Special care should be taken if it is essential that you drive while undergoing treatment especially if you are lacking strength or are in a debilitated condition.
Kidney
CAUTION
Zavedos 5mg Capsule should be used with caution in patients with kidney disease. Dose adjustment of Zavedos 5mg Capsule may be needed. Please consult your doctor.
Get kidney function tests done before the start of this medicine.
Liver
CAUTION
Zavedos 5mg Capsule should be used with caution in patients with liver disease. Dose adjustment of Zavedos 5mg Capsule may be needed. Please consult your doctor.
Get liver function tests done before the start of this medicine.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
No alternate brands found for this medicine

Quick Tips

  • Inform your doctor if you have or have had heart disease or any gastrointestinal disorders.
  • Men are advised to follow contraceptive measures for at least 3 months after completion of treatment with idarubicin.
  • Vaccination with a live vaccine should be avoided.
  • Liver and kidney function should be evaluated with conventional clinical laboratory tests (using serum bilirubin and serum creatinine as indicators) prior to, and during treatment.
  • Blood uric acid levels, potassium, calcium phosphate, and creatinine should be evaluated after initial treatment.
  • Idarubicin can cause dizziness and, therefore, caution has to be taken before operating an automobile or machinery or engaging in activities requiring mental alertness and coordination.

Patient Concerns

arrow
I've migraine . i can't stay for even 15 minutes in sunlight can't even take cheese . i consulted many doctors i can't get rid of it. I've taken many medicines .
Dr. Ravindra Srivastava
Neuro Surgery
TAB.CIPLAR LA 20MG TDS. TAB. RIZACT 5MG FOR ACUTE ATTACKS.
I want to know about Acute Lymphoblastic Leukemia CNS Relapse protocol followed by standard doctors.
Dr. Vijay Sharnangat
Medical Oncology and Hematology
What you want know
arrow
Do you have any questions related to Zavedos 5mg Capsule ?

FAQs

Q. Is Zavedos a vesicant?

Zavedos can cause inflammation of the vein in which it is administered; and irritation and ulceration of surrounding tissue, if leakage occurs at the site of intravenous administration

Q. What is Zavedos used for?

Zavedos is used in the treatment of acute myeloid leukaemia (a type of cancer of the white blood cells) in combination with other medications and breast cancer in advance stage after failure with other medications

Q. How does Zavedos work?

Zavedos acts by inhibiting the growth of cancer cells.

Related Products

Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 952.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 686-87.
  3. Idarubicin. Ramsgate Road Sandwich: Pfizer Limited; 2002 [revised Aug. 2018]. [Accessed 27 Mar. 2019] (online) Available from:External Link
  4. National Cancer Institute. Idarubicin. [Accessed 27 Mar. 2019] (online) Available from:External Link
Manufacturer/Marketer Address
The Capital, 1802, 18th Floor , Plot No. C-70, ‘G’ Block , Bandra Kurla Complex, Bandra East , Mumbai – 400051.
A licensed vendor partner from your nearest location will deliver Zavedos 5mg Capsule. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
1264
MRP1660.48  24% OFF
1 Capsule in 1 strip
Add To Cart
Additional offers
Amazon Pay: Get up to ₹300 cashback (min cashback ₹20) on orders above ₹100 with Amazon Pay. Offer valid once per user between 1st Feb to 29th Feb.
Show more show_more

INDIA’S LARGEST HEALTHCARE PLATFORM

150M+
Visitors
25M+
Orders Delivered
1000+
Cities
Get the link to download App
Reliable

All products displayed on 1mg are procured from verified and licensed pharmacies. All labs listed on the platform are accredited

Secure

1mg uses Secure Sockets Layer (SSL) 128-bit encryption and is Payment Card Industry Data Security Standard (PCI DSS) compliant

Affordable

Enjoy 20% off on allopathy medicines, up to 50% off on health products, up to 80% off on lab tests and free doctor consultations

India's only LegitScript and ISO/IEC 27001 certified online healthcare platform
Know More About 1mgdownArrow
Access medical and health information

1mg provides you with medical information which is curated, written and verified by experts, accurate and trustworthy. Our experts create high-quality content about medicines, diseases, lab investigations, Over-The-Counter (OTC) health products, Ayurvedic herbs/ingredients, and alternative remedies.

Order medicines online

Get free medicine home delivery in over 1000 cities across India. You can also order Ayurvedic, Homeopathic and other Over-The-Counter (OTC) health products. Your safety is our top priority. All products displayed on 1mg are procured from verified and licensed pharmacies.

Book lab tests

Book any lab tests and preventive health packages from certified labs and get tested from the comfort of your home. Enjoy free home sample collection, view reports online and consult a doctor online for free.

Consult a doctor online

Got a health query? Consult doctors online from the comfort of your home for free. Chat privately with our registered medical specialists to connect directly with verified doctors. Your privacy is guaranteed.