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Zavedos 25mg Capsule

Idarubicin (25mg)
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Zavedos 25mg Capsule is used in the treatment of some kinds of blood cancer (leukemia). It may be also used to treat other conditions, as determined by the doctor. It is sometimes used with certain other medicines as part of combination chemotherapy.

Written By Dr. Subita Alagh, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 25 Nov 2025 | 03:05 PM (IST)
₹5621 MRP ₹6117.198% off 
 
 
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General Information

The content is shown in English
Zavedos 25mg Capsule image
Zavedos 25mg Capsule image

Product introduction

Zavedos 25mg Capsule can be taken with or without food, but try to have it at the same time every day to get most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include vomiting, nausea, infection, hair loss, and fever. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels.

Before taking it, tell your doctor if have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of Zavedos Capsule

  • Blood cancer (Acute lymphocytic leukemia)

Benefits of Zavedos Capsule

Blood cancer (Acute lymphocytic leukemia)
Acute lymphocytic leukemia (ALL) is a type of blood cancer where the bone marrow produces too many immature white blood cells, crowding out healthy cells and affecting normal blood function. Zavedos 25mg Capsule helps destroy these cancer cells, reducing their growth and spread, which supports recovery and improves overall treatment outcomes.

Side effects of Zavedos Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Zavedos
  • Vomiting
  • Nausea
  • Infection
  • Hair loss
  • Fever
  • Increased liver enzymes
  • Peripheral neuropathy (tingling and numbness of feet and hand)
  • Stomatitis (Inflammation of the mouth)
  • Bleeding
  • Myelosuppression
  • Seizure

How to use Zavedos Capsule

Take this medicine in the dose and duration as advised by your doctor. Zavedos 25mg Capsule may be taken with or without food.

How Zavedos Capsule works

Zavedos 25mg Capsule is an anti-cancer medication. It works by suppressing the activity of an enzyme (topoisomerase II) involved in DNA multiplication of the cancer cells. It also forms harmful chemicals (free radicals) which cause DNA damage. This slows the growth of cancer cells and eventually kills them.

Quick tips

  • Zavedos 25mg Capsule should be taken with or without food but at the same time every day.
  • Do not skip any dose and complete the course as suggested by your doctor.
  • Use an effective method of birth control to avoid pregnancy while taking this medication.
  • Your doctor may get regular blood tests done to monitor your blood uric level, liver function, blood cell count in your blood.
  • Inform your doctor if you experience dizziness, fever, shortness of breath and itchy rash.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Zavedos 25mg Capsule. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Zavedos 25mg Capsule is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

UNSAFE
Zavedos 25mg Capsule is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving

Driving

UNSAFE
Zavedos 25mg Capsule may cause side effects that could affect your ability to drive.
Special care should be taken if it is essential that you drive while undergoing treatment especially if you are lacking strength or are in a debilitated condition.
Kidney

Kidney

CAUTION
Zavedos 25mg Capsule should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Get kidney function tests done before the start of this medicine.
Liver

Liver

CAUTION
Zavedos 25mg Capsule should be used with caution in patients with liver disease. Dose adjustment may be needed.
Get liver function tests done before the start of this medicine.

Interaction with drugs

Taking Zavedos with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Life-threatening

Natalizumab (Injection Route)

Do not consume Natalizumab with Idarubicin.
Severe

Amiodarone (Oral Route)

Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence.
Severe

Amiodarone (Injection Route)

Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence.
Severe

Artemether (Injection Route)

Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence.
Severe

Artemether (Oral Route)

Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence.

Frequently asked questions

Zavedos 25mg Capsule can cause inflammation of the vein in which it is administered; and irritation and ulceration of surrounding tissue, if leakage occurs at the site of intravenous administration.
Zavedos 25mg Capsule is used in the treatment of acute myeloid leukaemia (a type of cancer of the white blood cells) in combination with other medications and breast cancer in advance stage after failure with other medications.
Zavedos 25mg Capsule acts by inhibiting the growth of cancer cells.

Fact Box

Chemical Class

Anthracyclines

Habit Forming

No

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Other Anticancer Agents

References

  1. Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 952.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 686-87.
  3. Idarubicin. Ramsgate Road Sandwich: Pfizer Limited; 2002 [revised Aug. 2018]. [Accessed 27 Mar. 2019] (online) Available from:
  4. National Cancer Institute. Idarubicin. [Accessed 27 Mar. 2019] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Pfizer Ltd
Address: The Capital, 1802, 18th Floor , Plot No. C-70, ‘G’ Block , Bandra Kurla Complex, Bandra East , Mumbai – 400051.

Vendor Details

Country of origin: India
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