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Xpreza Injection

Azacitidine (100mg)

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Xpreza Injection is used in the treatment of some kinds of blood cancer. It is used for the treatment of adult patients with all subtypes of Myelodysplastic Syndrome (MDS). It may be also used to treat other conditions, as determined by the doctor.

Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 25 Nov 2025 | 03:05 PM (IST)

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General Information

Contains

Azacitidine (100mg)

Marketer

Natco Pharma Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Xpreza Injection is given as an injection under the medical supervision of a doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include injection site reactions (pain, swelling, redness), vomiting, weakness, and nausea. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. You must inform your doctor before taking any vaccination while on treatment with this medicine. Regular blood tests are required to check your blood cells along with the heart, liver, and kidney.

Before taking it, tell your doctor if you have liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding.

Uses of Xpreza Injection

Benefits of Xpreza Injection

Blood cancer
Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body's ability to fight infection. Xpreza Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

Treatment of Myelodysplastic syndrome
Xpreza Injection is used to treat myelodysplastic syndrome, a group of conditions in which the bone marrow produces blood cells that are abnormal in structure and function, and does not produce enough healthy blood cells. Xpreza Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is an effective, yet very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

Side effects of Xpreza Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Xpreza

Injection site reactions (pain, swelling, redness)
Vomiting
Weakness
Nausea
Decreased potassium level in blood
Bruise
Fever
Chills
Diarrhea
Constipation

How to use Xpreza Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Xpreza Injection works

Xpreza Injection is an anticancer medication. It works by interfering with the growth of genetic material (DNA and RNA) of the cancer cells in leukaemia. This kills the cancer cells and helps in normal maturation and growth of young blood cells in the bone marrow.

All substitutes for Xpreza Injection

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine.
Inform your doctor immediately if you notice any signs of infection such as fever, sore throat, rash or severe diarrhea.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Xpreza Injection. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Xpreza Injection is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

UNSAFE

Xpreza Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

UNSAFE

Xpreza Injection may cause side effects that could affect your ability to drive.
Xpreza Injection can cause side effects such as tiredness and this may affect your ability to drive.

Kidney

CAUTION

Xpreza Injection should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

CAUTION

Xpreza Injection should be used with caution in patients with liver disease. Dose adjustment may be needed.
Use of Xpreza Injection is not recommended in patients with advanced liver cancer.

Frequently asked questions

Is Xpreza Injection a vesicant?

Xpreza Injection is not a vesicant and is not known to cause severe local tissue damage upon extravasation (leaking of injected Xpreza Injection into the surrounding tissues from the site of administration) when injected

Does Xpreza Injection cause hair loss?

No, Xpreza Injection is not known to cause hair los

Is Xpreza Injection chemotherapy?

Yes. Xpreza Injection is chemotherapy and a cytotoxic drug used in the treatment of various cancers. It is toxic to cancer cells and interferes with the cell's DNA synthesis, thus slowing down or stopping its growth and multiplication (cytotoxic effect)

Is Xpreza Injection a cytotoxic drug?

Yes. Xpreza Injection is a cytotoxic drug.

Fact Box

Chemical Class

Glycosylamines

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Antimetabolites

Related lab tests

Bone Marrow Smear Microscopy Examination

Complete Blood Count

Peripheral Smear Examination

References

Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1700.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 112-13.
Azacitidine. Uxbridge, UK: Celgene Ltd.; 2008 [revised 30 Jul. 2018]. [Accessed 26 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:

User feedback

What are you using Xpreza Injection for?

Blood cancer

100%

How much was the improvement?

Poor

50%

Excellent

33%

Average

17%

What were the side-effects while using Xpreza Injection?

Decreased potassium level in blood

33%

Nausea

33%

Fever

33%

How do you take Xpreza Injection?

With or without food

100%

Please rate Xpreza Injection on price

Expensive

100%

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Natco Pharma Ltd
Address: Natco House, Road No.2, Banjara Hills, Hyderabad-500 034, India

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Xpreza Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

Lab tests offered by us

Why we need a prescription?

Xpreza Injection

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Xpreza Injection

Benefits of Xpreza Injection

Side effects of Xpreza Injection

How to use Xpreza Injection

How Xpreza Injection works

All substitutes for Xpreza Injection

Azadine Injection

Azacytin Injection

Azaplast Injection

Myaza Injection

AZAshine 100mg Injection

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

Is Xpreza Injection a vesicant?

Does Xpreza Injection cause hair loss?

Is Xpreza Injection chemotherapy?

Is Xpreza Injection a cytotoxic drug?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Bone Marrow Smear Microscopy Examination

Complete Blood Count

Peripheral Smear Examination

References

User feedback

What are you using Xpreza Injection for?

How much was the improvement?

What were the side-effects while using Xpreza Injection?

How do you take Xpreza Injection?

Please rate Xpreza Injection on price

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

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