Author Details
Written By
MMST, MBBS
Reviewed By
MD (Pharmacology), MBBS
Last updated:
18 Feb 2020 | 05:25 PM (IST)
Want to know more?
Read Our Editorial Policy
Have issue with the content?
Report Problem

Azadine Injection

Prescription Required
SALT COMPOSITION
Storage
Store at room temperature (10-30°C)

Overview

Introduction

Azadine Injection is used in the treatment of some kinds of blood cancer. It is used for the treatment of adult patients with all subtypes of Myelodysplastic Syndrome (MDS). It may be also used to treat other conditions, as determined by the doctor.

Azadine Injection is given as an injection under the medical supervision of a doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include injection site reactions (pain, swelling, redness), vomiting, weakness, and nausea. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. You must inform your doctor before taking any vaccination while on treatment with this medicine. Regular blood tests are required to check your blood cells along with the heart, liver, and kidney.

Before taking it, tell your doctor if you have liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding.

Uses of Azadine Injection

Side effects of Azadine Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Azadine

  • Injection site reactions (pain, swelling, redness)
  • Vomiting
  • Weakness
  • Nausea
  • Decreased potassium level in blood
  • Bruise
  • Fever
  • Chills
  • Diarrhea
  • Constipation

How to cope with side effects?

The occurrence of side effects varies from person to person. The following are a few ways of dealing with some of the common side effects. However, consult your doctor if these persist.

  • Coping with Injection site reactions (pain, swelling, redness)
    Try to change the area of injection and the exact site of injection each time. Apply a cold compress to the injection site. These symptoms are usually mild and should only last a few hours. You can ask your doctor to recommend a medicine if it is bothering you.
  • Coping with Vomiting
    You can help yourself by eating small, frequent meals rather than large ones and drinking plenty of fluids. Eat slowly. Avoid fatty, fried, spicy and very sweet foods. Eat cold or slightly warm food if the smell of cooked or cooking food makes you feel sick. Get plenty of fresh air. You could also try chewing ginger or drinking ginger tea. Eat bananas to replace potassium in your blood which can drop if you are sick (vomit). Use oral rehydration salts to replace vitamins and minerals lost through being sick. There are some medicines that can help you stop feeling sick. Speak to your doctor if your condition does not improve.
  • Coping with Weakness
    Make sure you rest and drink plenty of fluids. Eat a well-balanced diet to keep your energy levels up. Do not drink too much alcohol. Do not drive or use tools or machinery until you feel better. Other things that can help include doing some gentle exercise every day, prioritizing and pacing your activities and having a short nap if you need to. If you are still having problems after a week, speak to your doctor, as they may want to change you to a different type of medicine.
  • Coping with Nausea
    You can help yourself by eating small, frequent meals rather than large ones and drinking plenty of fluids. Eat slowly. Avoid fatty, fried, spicy and very sweet foods. Eat cold or slightly warm food if the smell of cooked or cooking food makes you feel sick. Get plenty of fresh air. You could also try chewing ginger or drinking ginger tea. Eat bananas to replace potassium in your blood which can drop if you are sick (vomit). Use oral rehydration salts to replace vitamins and minerals lost through being sick. There are some medicines that can help you stop from feeling sick. Speak to your doctor if your condition does not improve.
  • Coping with Decreased potassium level in blood
    You will need a blood test to find out if your potassium levels are low. Your doctor might suggest using a salt substitute which contains potassium. Some foods which are good sources of potassium include fruit (especially bananas), vegetables, pulses, nuts and seeds, milk, fish, chicken and bread.
  • Coping with Diarrhea
    Keep up your intake of fluids and electrolytes (sugars and salts) to avoid getting dehydrated. Eat less fiber (avoid raw fruits, fruit juice and vegetables). Talk to your doctor about possible medication to manage diarrhea. Ask about reducing the dosage of your drug or other suitable treatments.
  • Coping with Constipation
    Try to eat foods which are high in fiber such as fresh fruits, vegetables and cereals to increase the bulk and consistency of bowel movements. Drink plenty of water or non-alcoholic drinks and stay hydrated to promote healthy digestion. Increasing physical activities such as walking, yoga and regular exercise can also be helpful. If your condition does not improve, you can ask your doctor to prescribe you laxative medicine.

How to use Azadine Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Azadine Injection works

Azadine Injection is an anticancer medication. It works by interfering with the growth of genetic material (DNA and RNA) of the cancer cells in leukaemia. This kills the cancer cells and helps in normal maturation and growth of young blood cells in the bone marrow.

Safety Advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Azadine Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Azadine Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breastfeeding
UNSAFE
Azadine Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
UNSAFE
Azadine Injection may cause side effects which could affect your ability to drive.
Azadine Injection can cause side effects such as tiredness and this may affect your ability to drive.
Kidney
CAUTION
Azadine Injection should be used with caution in patients with kidney disease. Dose adjustment of Azadine Injection may be needed. Please consult your doctor.
Liver
CAUTION
Azadine Injection should be used with caution in patients with liver disease. Dose adjustment of Azadine Injection may be needed. Please consult your doctor.
Use of Azadine Injection is not recommended in patients with advanced liver cancer.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Azadine Injection
₹131.7/ml of Injection
Azaplast Injection
RPG Life Sciences Ltd
₹3373/Injection
2461% costlier
Xpreza Injection
Natco Pharma Ltd
₹4283.17/Injection
3152% costlier
₹5043.11/Injection
3729% costlier
Azacytin Injection
Dr Reddy's Laboratories Ltd
₹5079.5/Injection
3757% costlier
Azzure 100mg Injection
Sun Pharmaceutical Industries Ltd
₹7701.56/Injection
5748% costlier

Quick Tips

  • Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine.
  • Inform your doctor immediately if you notice any signs of infection such as fever, sore throat, rash or severe diarrhea.

Fact Box

Chemical Class
Pyrimidine Nucleoside Analogue
Habit Forming
No

Patient Concerns

arrow
Can blood cancer patients 1st stage do sex with normal girl Sir a blood cancer patients do sex with normal girl can any problem or cause doing with girl or side effect give suggestions Thanks
Dr. Vijay Sharnangat
Medical Oncology and Hematology
Wait till blood cancer gets cured.
Blood Cancer. Is there any medicine to cure blood cancer.
Dr. Aanchal Maheshwari
Ayurveda
Case has to be seen in person
arrow
Do you have any questions related to Azadine Injection ?

User Feedback


FAQs

Q. Is Azadine a vesicant?

Azadine is not a vesicant and is not known to cause severe local tissue damage upon extravasation (leaking of injected Azadine into the surrounding tissues from the site of administration) when injected

Q. Does Azadine cause hair loss?

No, Azadine is not known to cause hair los

Q. Is Azadine chemotherapy?

Yes. Azadine is chemotherapy and a cytotoxic drug used in the treatment of various cancers. It is toxic to cancer cells and interferes with the cell's DNA synthesis, thus slowing down or stopping its growth and multiplication (cytotoxic effect)

Q. Is Azadine a cytotoxic drug?

Yes. Azadine is a cytotoxic drug.

Related Products

Want to share the information?

Disclaimer:

1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1700.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 112-13.
  3. Azacitidine. Uxbridge, UK: Celgene Ltd.; 2008 [revised 30 Jul. 2018]. [Accessed 26 Mar. 2019] (online) Available from:External Link
  4. Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:External Link

Manufacturer/Marketer Address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
A licensed vendor partner from your nearest location will deliver Azadine Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
MRP3951.1  Get 15% OFF
Best Price
₹3358.43
30 ml in 1 vial
Add To Cart
Additional offers
Paytm: Pay with Paytm and get cashback up to ₹500. Minimum cashback to be won is ₹50. Valid only for new Paytm customers with minimum order value of ₹1000 from 1st August to 31st August, 2020.
Show more show_more

INDIA’S LARGEST HEALTHCARE PLATFORM

150M+
Visitors
25M+
Orders Delivered
1000+
Cities
Get the link to download App
Reliable

All products displayed on 1mg are procured from verified and licensed pharmacies. All labs listed on the platform are accredited

Secure

1mg uses Secure Sockets Layer (SSL) 128-bit encryption and is Payment Card Industry Data Security Standard (PCI DSS) compliant

Affordable

Find affordable medicine substitutes, save up to 50% on health products, up to 80% off on lab tests and free doctor consultations.

India's only LegitScript and ISO/IEC 27001 certified online healthcare platform
Know More About 1mgdownArrow
Access medical and health information

1mg provides you with medical information which is curated, written and verified by experts, accurate and trustworthy. Our experts create high-quality content about medicines, diseases, lab investigations, Over-The-Counter (OTC) health products, Ayurvedic herbs/ingredients, and alternative remedies.

Order medicines online

Get free medicine home delivery in over 1000 cities across India. You can also order Ayurvedic, Homeopathic and other Over-The-Counter (OTC) health products. Your safety is our top priority. All products displayed on 1mg are procured from verified and licensed pharmacies.

Book lab tests

Book any lab tests and preventive health packages from certified labs and get tested from the comfort of your home. Enjoy free home sample collection, view reports online and consult a doctor online for free.

Consult a doctor online

Got a health query? Consult doctors online from the comfort of your home for free. Chat privately with our registered medical specialists to connect directly with verified doctors. Your privacy is guaranteed.