Xgeva Solution for Injection is a medicine used in the treatment of osteoporosis in postmenopausal women and in men at increased risk of fractures. It makes the bones strong and reduce the risk of fractures.

Xgeva Solution for Injection is given by a healthcare professional and should not be self-administered. You should use it regularly and at the same time each day to get maximum benefit from it. Continue using it as recommended by your doctor and complete the dose even if you feel better. To make it more effective, take adequate amount of calcium and vitamin D supplements while on treatment with this medicine.

Some common side effects of this medicine include headache, pain in extremity, musculoskeletal pain, nerve pain, constipation, and rash. Talk to your doctor if any of these side effects does not go away with time or get worse. Your doctor may help with ways to reduce or prevent these symptoms.

To make sure the medicine is safe for you, before taking it, let your doctor know of all the other medicines you are taking. It is important for pregnant and breastfeeding mothers to ask the advice of their doctors before using this medicine.

Uses of Xgeva Solution for Injection

Osteoporosis

Benefits of Xgeva Solution for Injection

In Osteoporosis

Osteoporosis is a common condition that weakens bones, making them fragile and more likely to break. It often occurs in women after menopause. This condition can be treated with bone-strengthening medicines. Xgeva Solution for Injection slows down the rate at which bone is broken down in your body. This maintains bone density and reduces your risk of breaking a bone. The injection is given by a doctor or nurse and should not be self-administered.
You can help improve the strength of your bones by doing regular exercise (especially weight-bearing exercise), eating healthy foods containing calcium and Vitamin D and reducing your consumption of alcohol and tobacco. Supplements of calcium and Vitamin D3 are also effective.

Side effects of Xgeva Solution for Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Xgeva

Musculoskeletal (bone, muscle or joint) pain
Pain in extremities
Nerve pain
Constipation
Rash
Headache

How to use Xgeva Solution for Injection

Your doctor or nurse will guide you how to use this medicine.

How Xgeva Solution for Injection works

Xgeva Solution for Injection is a monoclonal antibody. It binds to a protein that causes bone loss, thereby strengthening the bone and minimizing the risk of fractures.

Safety advice

Alcohol

CAUTION

Caution is advised when consuming alcohol with Xgeva Solution for Injection. Please consult your doctor.

Pregnancy

UNSAFE

Xgeva Solution for Injection is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.

Breast feeding

CONSULT YOUR DOCTOR

Xgeva Solution for Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

SAFE

Xgeva Solution for Injection does not usually affect your ability to drive.

Kidney

CAUTION

Xgeva Solution for Injection should be used with caution in patients with severe kidney disease. Dose adjustment of Xgeva Solution for Injection may be needed. Please consult your doctor.

Liver

CAUTION

Xgeva Solution for Injection should be used with caution in patients with severe liver disease. Dose adjustment of Xgeva Solution for Injection may be needed. Please consult your doctor.

What if you forget to take Xgeva Solution for Injection?

If you miss a dose of Xgeva Solution for Injection, please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

No substitutes found for this medicine

Quick tips

Xgeva Solution for Injection is a medication used to treat thinning of the bones (called osteoporosis).
Take calcium and vitamin D to help build your bones when taking Xgeva Solution for Injection.
Do not take if you are pregnant or plan to become pregnant.
May cause a rare problem of the jaw (osteonecrosis), mostly seen after a dental procedure. Tell your doctor if you develop sudden jaw pain.
Xgeva Solution for Injection may also increase the risk of infection. Avoid being close to people with cold, flu or other contagious illnesses.
Tell your doctor if you develop a rash while taking Xgeva Solution for Injection.

Fact Box

Chemical Class

Monoclonal antibody (mAb)

Habit Forming

Therapeutic Class

PAIN ANALGESICS

Patient concerns

Teriparatide is this injection advisable?

Dr. Akshat Goel

Orthopaedics

Yes, it's good in Osteoporosis

Details About osteoporosis treatment

Dr. Akshat Goel

Orthopaedics

Take Calcium and Vitamin-D3 supplements

User feedback

Patients taking Xgeva Solution for Injection

Once A Month

72%

Once A Day

14%

Once A Week

Twice A Month

Twice A Week

What are you using Xgeva Solution for Injection for?

Others

100%

How much was the improvement?

Excellent

55%

Average

27%

Poor

18%

What were the side-effects while using Xgeva Solution for Injection?

No Side Effec*

71%

Pain in extre*

14%

Abdominal pai*

14%

*No Side Effect, Pain in extremity, Abdominal pain

How do you take Xgeva Solution for Injection?

With food

75%

Empty stomach

12%

With or witho*

12%

*With or without food

Please rate Xgeva Solution for Injection on price

Expensive

79%

Average

21%

FAQs

Q. How long can you stay on Xgeva Solution for Injection?

There is no optimal duration of treatment of osteoporosis with Xgeva Solution for Injection. The patient’s response and tolerability to the medicine is continuously monitored through periodic assessments, especially after 5 years of use of Xgeva Solution for Injection. Depending on this, the duration of taking Xgeva Solution for Injection is decided.

Q. Does Xgeva Solution for Injection cause hair loss?

Yes, hair loss is a common side effect of Xgeva Solution for Injection though it does not affect everyone. Discuss with your doctor if you have concerns regarding your hair loss.

Q. Is Xgeva Solution for Injection a chemotherapy drug?

Xgeva Solution for Injection is not a chemotherapy drug. It is a protein (monoclonal antibody) that interferes with the action of another protein in order to treat bone loss and osteoporosis. Treatment with Xgeva Solution for Injection makes the bones stronger and less likely to break.

Q. How is Xgeva Solution for Injection given and how often?

Xgeva Solution for Injection is available as an injection and is given by a healthcare professional. It is given once in 6 months. Your doctor may also advise you to take calcium and vitamin D while taking Xgeva Solution for Injection.

Q. Can Xgeva Solution for Injection be taken during pregnancy?

No, pregnant women should not take Xgeva Solution for Injection. You must use an effective method of birth control during and for at least 5 months after the last dose of Xgeva Solution for Injection if you can become pregnant.

Q. How should Xgeva Solution for Injection be stored?

Xgeva Solution for Injection should be stored in a refrigerator at 36°F to 46°F (2°C to 8°C) in the original carton. Warm temperatures can make it ineffective, and therefore proper storage is necessary. When you remove it from the refrigerator, keep it at room temperature [up to 77°F (25°C)] in the original carton and use it within 14 days.

Q. Does Xgeva Solution for Injection cause osteonecrosis of the jaw?

Osteonecrosis is a rare side effect of Xgeva Solution for Injection. It refers to the damage caused to the bone of jaw. To avoid this, you should maintain good oral hygiene and receive routine dental check ups while taking Xgeva Solution for Injection. Contact your doctor and dentist immediately if you experience any problems with your mouth or teeth such as loose teeth, discharge, pain or swelling, or non-healing of sores. These could be signs of osteonecrosis of jaw.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Bikle DD. Agents That Affects Bone Mineral Homoestasis. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 766.
Friedman PA. Agents Affecting Mineral Ion Homeostasis and Bone Turnover. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1299.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 370.
Drugs.com. Denosumab. [Accessed 02 Apr. 2019] (online) Available from:
Denosumab. Milton Road, Cambridge: Amgen Ltd.; 2010 [revised Jun. 2018]. [Accessed 02 Apr. 2019] (online) Available from:
Denosumab [Prescribing Information]. Thousand Oaks, California: Amgen Manufacturing Limited; 2013. [Accessed 20 Feb. 2024] (online) Available from:

Marketer details

Name: Dr Reddy's Laboratories Ltd

Address: Dr. Reddy's Laboratories Ltd., Village Malpur, P.O.Bhud, Baddi, Dist. Solan, H.P.

Country of origin: India
Expires on or after: July, 2024

A licensed vendor partner from your nearest location will deliver Xgeva Solution for Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

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Xgeva Solution for Injection

Product introduction

Uses of Xgeva Solution for Injection

Benefits of Xgeva Solution for Injection

In Osteoporosis

Side effects of Xgeva Solution for Injection

Common side effects of Xgeva

How to use Xgeva Solution for Injection

How Xgeva Solution for Injection works

Safety advice

What if you forget to take Xgeva Solution for Injection?

All substitutes

Quick tips

Fact Box

Patient concerns

User feedback

FAQs

Q. How long can you stay on Xgeva Solution for Injection?

Q. Does Xgeva Solution for Injection cause hair loss?

Q. Is Xgeva Solution for Injection a chemotherapy drug?

Q. How is Xgeva Solution for Injection given and how often?

Q. Can Xgeva Solution for Injection be taken during pregnancy?

Q. How should Xgeva Solution for Injection be stored?

Q. Does Xgeva Solution for Injection cause osteonecrosis of the jaw?

Related ayurvedic ingredients

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Disclaimer:

References

Marketer details

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