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Xenadom 250 Tablet


Overview

Introduction

Xenadom 250 Tablet is a combination of two medicines used in the prevention of migraine. It blocks the release of certain chemical messengers that cause pain, inflammation, and fever. It also blocks the signals in the brain that cause nausea and vomiting associated with migraine.

Xenadom 250 Tablet may be prescribed alone or in combination with another medicine. It can be taken with or without food. The dose and duration will depend on the severity of your condition and how well it helps your symptoms. Use it regularly and do not discontinue using it until the doctor tells you it is alright to stop.

Using of the medicine may cause few common side effects such as flu-like symptoms, indigestion, and dryness in mouth. If you experience any such side effects that do not go away or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms. In general, you should try to use the smallest amount necessary to control your symptoms.

Before using the medicine, you should tell your doctor if you have any other illnesses or disorders. It may also affect, or be affected by, some other medicines you are using so let your doctor know all the other medicines you are taking. It should be used with caution in patients who are alcoholic or have liver or kidney disease. Pregnant and breastfeeding women should consult their doctors first before using the medicine.

Uses of Xenadom Tablet

Side effects of Xenadom Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Xenadom

  • Flu-like symptoms
  • Indigestion
  • Dryness in mouth

How to cope with side effects?

The occurrence of side effects varies from person to person. The following are a few ways of dealing with some of the common side effects. However, consult your doctor if these persist.

  • Coping with Flu-like symptoms
    Get plenty of rest as exhausting or stressing out yourself could aggravate your condition. You should drink plenty of fluids as it will keep your throat moist and comfortable. Try taking steam inhalation. The moisture can ease your breathing and loosen mucus. You can consider sipping warm water or tea with honey and lemon. This will keep your nose and throat from being too dry. Using an air humidifier may also help. You can also gargle with salt water several times a day. See your doctor if your symptoms last longer than 3 weeks or get worse quickly. Avoid alcohol and do not smoke as they can aggravate your conditions.
  • Coping with Indigestion
    Try taking your medicine with a meal or snack, or shortly after eating. It might help to eat smaller and more frequent meals, and to eat and drink slowly. Avoid foods which can irritate your stomach such as carbonated soft drinks, caffeine, fatty and spicy foods, mints and citrus fruits. Quit smoking and alcohol because they increase the symptoms. Do not eat for 3 or 4 hours before going to bed. Try raising the head of your bed at night or use extra pillows. Ask your doctor or pharmacist about medicines that may help, such as antacids, if your condition does not improve.
  • Coping with Dryness in mouth
    Keep a drink available that you can sip through the day. Rinse your mouth with warm salted water and chew sugarless gum or hard candy. Try breathing through your nose more often than your mouth. Avoid caffeinated beverages, smoking and alcohol because they can make your condition worse. Use lip balm if your lips are also dry. Try to avoid foods that are acidic (like lemons), spicy, salty or sugary. If this side effect bothers you or does not go away, talk to your doctor about artificial saliva products or other suitable treatments.

How to use Xenadom Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Xenadom 250 Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Xenadom Tablet works

Xenadom 250 Tablet is a combination of two medicines: Naproxen and Domperidone. Naproxen is a non-steroidal anti-inflammatory drug (NSAID) which works by blocking the release of certain chemical messengers that cause pain due to migraine. Domperidone is a prokinetic which works on the region in the brain that controls vomiting associated with migraine. It also increases the movement of the stomach and intestines, allowing food to move more easily through the stomach.

Safety Advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Xenadom 250 Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Xenadom 250 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breastfeeding
SAFE IF PRESCRIBED
Xenadom 250 Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving
UNSAFE
Xenadom 250 Tablet may cause side effects which could affect your ability to drive.
Xenadom 250 Tablet may make you feel dizzy, depressed, sleepy, tired, or make it difficult to sleep. It may also affect your vision. This may affect your driving ability.
Kidney
CAUTION
Xenadom 250 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Xenadom 250 Tablet may be needed. Please consult your doctor.
Liver
CAUTION
Xenadom 250 Tablet should be used with caution in patients with liver disease. Dose adjustment of Xenadom 250 Tablet may be needed. Please consult your doctor.
Use of Xenadom 250 Tablet is not recommended in patients with moderate and severe liver disease.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Xenadom 250 Tablet
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Quick Tips

  • You have been prescribed Xenadom 250 Tablet for prevention of migraine headaches.
  • Do not take it to treat an acute attack of migraine.
  • Some tips that may help avoid a migraine attack:
    • Have your meals at the same time everyday
    • Avoid bright lights and extreme temperatures
    • Avoid loud music and noisy places
    • Avoid chocolates,  cheese, processed food, alcohol and smoking
    • Get enough sleep and avoid stress
  • It may cause sleepiness. Do not drive or do anything that requires mental focus until you know how Xenadom 250 Tablet affects you.
  • Avoid consuming alcohol as it may cause new and worse headaches.
  • Keep taking it every day, as prescribed by your doctor, even if you do not have any symptoms.

Fact Box

Habit Forming
No

Patient Concerns

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Sir i am having sometimes mild pain above my left ear forehead. Sometimes it exists for 2 to 3 .then auto matically stop after 6 to 7 days again occurs
Dr. Vikas Sharma
Neurology
Cud be migraine Get mri brain done n show 2 neurologist Meanwhile try tab naproxen 250 mg sos
i usually get migraine pain due to tension developed by using computers. I am Photophobic. when ever i travel a lot in bright sunlight i get headaches . i used to take DART Tablet. which has a combination of Paracetamol(300 mg),Caffeine(50 mg),Phenazone(150 mg). DART helped me to deal with this. Recent days i am not able to get this tablet. can you help me getting the right substitute?? thanks in advance.
Dr. Pushkar Mani
Physician
take Capnea 20mg + calpol 250 mg simulataneously
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Do you have any questions related to Xenadom 250 Tablet ?

User Feedback


FAQs

Q. What is Xenadom?

Xenadom is a combination of two medicines: Naproxen and Domperidone. This combination helps in relieving the symptoms of migraine like headache, nausea and vomiting. Naproxen is a pain-killer that blocks the release of certain chemical messengers that cause headache. Domperidone is an anti-emetic agent (prokinetic). It increases the movement of the stomach and intestines, allowing food to move more easily through the stomach. This helps in relieving vomiting.

Q. Can I stop taking Xenadom when my migraine symptoms are relieved?

No, do not stop taking Xenadom until advised by your doctor.

Q. Can the use of Xenadom cause diarrhea?

Yes, the use of Xenadom can cause diarrhea. In case, you experience diarrhea, drink plenty of water or other fluids. Talk to your doctor if diarrhea persists and you notice any signs of dehydration, like less urination with dark coloured and strong-smelling urine. Do not take any other medicine without consulting a doctor.

Q. Are there any specific contraindications associated with the use of Xenadom?

The use of Xenadom is considered to be harmful for patients with known allergy to any of the components or excipients of this medicine or in patients with known allergy to other painkillers (NSAIDs). The use of this medicine should preferably be avoided in patients with a history of stomach ulcers or in patients with active, recurrent stomach ulcer/bleeding. It should also be avoided in patients with history of heart failure, high blood pressure, and liver or kidney disease.

Q. Can the use of Xenadom cause damage to kidneys?

Yes, the long-term use of Xenadom can cause damage to the kidneys. Normal kidneys produce a chemical called prostaglandins that protects them from damage. Use of painkillers lower the levels of prostaglandins in the body, which leads to kidney damage on long-term use. Use of painkillers is not recommended to patients with underlying kidney disease.

Q. Can I take a higher than the recommended dose of Xenadom?

No, taking a higher than the recommended dose of Xenadom can increase the risks of side effects. If you are experiencing increased severity of migraine attacks which are not relieved by the recommended doses, please consult your doctor for re-evaluation.

Q. What are the recommended storage conditions for Xenadom?

Keep this medicine in the container or the pack it came in, tightly closed. Store it as mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Related Products

Disclaimer:

1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Naproxen. Nutley, New Jersey: Roche Laboratories Inc. [Accessed 22 Apr. 2019] (online) Available from:External Link
  2. Domperidone and domperidone maleate. South Ruislip, Middlesex: Aurobindo Pharma - Milpharm Ltd.; 2003 [revised 14 Nov. 2017]. [Accessed 24 Jan. 2019] (online) Available from:External Link
  3. Drugs.com. Naproxen. [Accessed 22 Apr. 2019] (online) Available from:External Link
  4. Drugs.com. Domperidone. [Accessed 22 Apr. 2019] (online) Available from:External Link

Manufacturer/Marketer Address

Icon Life Sciences, Div. Of Mesmer Pharmaceuticals, No.202/6, Lane In.30, Phase-II, IDA, Cherlapally, Hyderabad, 500 051 AP
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