Comig 250 Tablet

Prescription Required
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Introduction

Comig 250 Tablet is a combination of two medicines used in the prevention of migraines. It blocks the release of certain chemical messengers that cause pain, inflammation, and fever. It also blocks the signals in the brain that cause nausea and vomiting associated with migraines.

Comig 250 Tablet may be prescribed alone or in combination with another medicine. It can be taken with or without food. The dose and duration will depend on the severity of your condition and how well it helps your symptoms. Use it regularly and do not discontinue using it until the doctor tells you it is alright to stop.

Using of the medicine may cause few common side effects such as flu-like symptoms, indigestion, and dryness in the mouth. If you experience any such side effects that do not go away or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms. In general, you should try to use the smallest amount necessary to control your symptoms.

Before using the medicine, you should tell your doctor if you have any other illnesses or disorders. It may also affect, or be affected by, some other medicines you are using so let your doctor know all the other medicines you are taking. It should be used with caution in patients who are alcoholics or have liver or kidney disease. Pregnant and breastfeeding women should consult their doctors first before using the medicine.

Uses of Comig Tablet

Benefits of Comig Tablet

In Prevention of Migraine

Comig 250 Tablet blocks chemicals responsible for pain sensation and also blocks signals that cause nausea/vomiting associated with migraines. By preventing and reducing the frequency of migraine headaches, it can help you carry out your daily activities and have a better quality of life.

Side effects of Comig Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Comig

  • Flu-like symptoms
  • Indigestion
  • Dryness in mouth

How to use Comig Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Comig 250 Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Comig Tablet works

Comig 250 Tablet is a combination of two medicines: Naproxen and Domperidone. Naproxen is a non-steroidal anti-inflammatory drug (NSAID) which works by blocking the release of certain chemical messengers that cause pain due to migraine. Domperidone is a prokinetic which works on the region in the brain that controls vomiting associated with migraine. It also increases the movement of the stomach and intestines, allowing food to move more easily through the stomach.

Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Comig 250 Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Comig 250 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
Comig 250 Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving
UNSAFE
Comig 250 Tablet may cause side effects which could affect your ability to drive.
Comig 250 Tablet may make you feel dizzy, depressed, sleepy, tired, or make it difficult to sleep. It may also affect your vision. This may affect your driving ability.
Kidney
CAUTION
Comig 250 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Comig 250 Tablet may be needed. Please consult your doctor.
Liver
CAUTION
Comig 250 Tablet should be used with caution in patients with liver disease. Dose adjustment of Comig 250 Tablet may be needed. Please consult your doctor.
Use of Comig 250 Tablet is not recommended in patients with moderate and severe liver disease.

What if you forget to take Comig Tablet?

If you miss a dose of Comig 250 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Comig 250 Tablet
₹6.27/Tablet
Pacinac NP 250mg/10mg Tablet
Gentech Healthcare Pvt Ltd
₹4.5/tablet
28% cheaper
Minado Tablet
Tas Med India Pvt Ltd
₹4.57/tablet
27% cheaper
Domstal NP 250mg/10mg Tablet
Torrent Pharmaceuticals Ltd
₹5.35/tablet
15% cheaper
₹5.45/tablet
13% cheaper
Naprodom 250mg Tablet
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₹5.98/tablet
5% cheaper

Quick tips

  • You have been prescribed Comig 250 Tablet for prevention of migraine headaches.
  • Do not take it to treat an acute attack of migraine.
  • Some tips that may help avoid a migraine attack:
    • Have your meals at the same time everyday
    • Avoid bright lights and extreme temperatures
    • Avoid loud music and noisy places
    • Avoid chocolates,  cheese, processed food, alcohol and smoking
    • Get enough sleep and avoid stress
  • It may cause sleepiness. Do not drive or do anything that requires mental focus until you know how Comig 250 Tablet affects you.
  • Avoid consuming alcohol as it may cause new and worse headaches.
  • Keep taking it every day, as prescribed by your doctor, even if you do not have any symptoms.

Fact Box

Habit Forming
No
Therapeutic Class
PAIN ANALGESICS

Patient concerns

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Before I go for urinal urine is comig out. Some times I feel the bladder is full and not able to control.
Dr. Praveen Pushkar
Urology
Get ultrasound kub with PVR n uroflowmetry
I am facing issue of headache from last 3-4 years.i have consulted allopathy and they have given me sibelum 10 for migrane and asked to take metopar(paracetamol) when ever pain is too much.i am nit taking sibelum now but i am taking metopar when ever required.so i want a homeopathy consultatation if it can be cured by homeopathy or the level of headache can be lowered. Currently i face headache once in a week and i had to take metopar. Kindly suggest. My weight 80 kg And i am taking some neuro medicines ( stalopam 10, amitone 10) I also have cholesterol and taking (atorec 20)
Dr. Faran Siddiqui
Homeopathy
Migraine and headache are two different things migraine is primarily headache of one side in symmetrically
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User feedback


FAQs

Q. What is Comig 250 Tablet?

Comig 250 Tablet is a combination of two medicines: Naproxen and Domperidone. This combination helps in relieving the symptoms of migraine like headache, nausea and vomiting. Naproxen is a pain-killer that blocks the release of certain chemical messengers that cause headache. Domperidone is an anti-emetic agent (prokinetic). It increases the movement of the stomach and intestines, allowing food to move more easily through the stomach. This helps in relieving vomiting.

Q. Can I stop taking Comig 250 Tablet when my migraine symptoms are relieved?

No, do not stop taking Comig 250 Tablet until advised by your doctor.

Q. Can the use of Comig 250 Tablet cause diarrhea?

Yes, the use of Comig 250 Tablet can cause diarrhea. In case, you experience diarrhea, drink plenty of water or other fluids. Talk to your doctor if diarrhea persists and you notice any signs of dehydration, like less urination with dark coloured and strong-smelling urine. Do not take any other medicine without consulting a doctor.

Q. Are there any specific contraindications associated with the use of Comig 250 Tablet?

The use of Comig 250 Tablet is considered to be harmful for patients with known allergy to any of the components or excipients of this medicine or in patients with known allergy to other painkillers (NSAIDs). The use of this medicine should preferably be avoided in patients with a history of stomach ulcers or in patients with active, recurrent stomach ulcer/bleeding. It should also be avoided in patients with history of heart failure, high blood pressure, and liver or kidney disease.

Q. Can the use of Comig 250 Tablet cause damage to kidneys?

Yes, the long-term use of Comig 250 Tablet can cause damage to the kidneys. Normal kidneys produce a chemical called prostaglandins that protects them from damage. Use of painkillers lower the levels of prostaglandins in the body, which leads to kidney damage on long-term use. Use of painkillers is not recommended to patients with underlying kidney disease.

Q. Can I take a higher than the recommended dose of Comig 250 Tablet?

No, taking a higher than the recommended dose of Comig 250 Tablet can increase the risks of side effects. If you are experiencing increased severity of migraine attacks which are not relieved by the recommended doses, please consult your doctor for re-evaluation.

Q. What are the recommended storage conditions for Comig 250 Tablet?

Keep this medicine in the container or the pack it came in, tightly closed. Store it as mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Naproxen. Nutley, New Jersey: Roche Laboratories Inc. [Accessed 22 Apr. 2019] (online) Available from:External Link
  2. Domperidone and domperidone maleate. South Ruislip, Middlesex: Aurobindo Pharma - Milpharm Ltd.; 2003 [revised 14 Nov. 2017]. [Accessed 24 Jan. 2019] (online) Available from:External Link
  3. Drugs.com. Naproxen. [Accessed 22 Apr. 2019] (online) Available from:External Link
  4. Drugs.com. Domperidone. [Accessed 22 Apr. 2019] (online) Available from:External Link

Manufacturer/Marketer address

305-307, Ansal Imperial Tower, C Block Community Centre, Naraina Vihar, New Delhi-110028, India
Country of origin: India

Expires on or after: March, 2022

A licensed vendor partner from your nearest location will deliver Comig 250 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
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