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Vortain 10 Tablet

Written By Dr. Sakshi Jain, MS, BDS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 22 Feb 2026 | 06:32 PM (IST)
Vortain 10 Tablet is a medicine prescribed to treat depression in adults. It belongs to a group of antidepressants known as serotonin modulator and stimulator (SMS). This medication helps to improve mood and energy levels, and reduce sadness and feelings of worthlessness in people with depression.
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Vortain 10 Tablet is currently sold out
Same composition alternative:
Voxitin 10 Tablet
₹183₹198.75
Available alternative from Alkem Laboratories
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Vortain 10 Tablet
Vortain 10 Tablet
strip of 10 tablets
₹154
₹170
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Same composition
Voxitin 10 Tablet
Voxitin 10 Tablet
strip of 10 tablets
by Alkem Laboratories Ltd
₹183
₹15.6 per tablet

₹156

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General Information

The content is shown in English
Vortain 10 Tablet image
Vortain 10 Tablet image
Vortain 10 Tablet image
Vortain 10 Tablet image
Vortain 10 Tablet image
Vortain 10 Tablet image

Product introduction

Vortain 10 Tablet may be taken with or without food but take it at the same time each day to get the most benefit. The dose and how often you need it will be decided by your doctor so that you get the right amount to control your symptoms. It may be increased gradually. If you have trouble sleeping it may be best to take this medicine in the morning. It may take a few weeks before you start to feel better. Do not change the dose or stop taking it without talking to your doctor, even if you feel well. Your condition may get worse or you may suffer unpleasant withdrawal symptoms. Let your doctor know if you do not see any improvement after four weeks.

Some common side effects of this medicine include vomiting, nausea, and constipation. Keep taking the medicine but talk to a doctor if these side effects bother you. There may be ways of preventing or reducing them. You should avoid driving or operating machinery until you know how this medicine affects you.

Before taking it, you should tell your doctor if you have epilepsy, diabetes, liver or kidney disease, heart problems, glaucoma, drug addiction or bipolar disorder. These may affect your treatment. Pregnant or breastfeeding women should also consult their doctor before taking it. Some other medicines may affect the way it works, especially other antidepressants and medicines called MAO inhibitors. Please tell your doctor about all the medicines you are taking to make sure you are safe.

Uses of Vortain Tablet

Benefits of Vortain Tablet

Depression
Vortain 10 Tablet works by increasing the level of a chemical called serotonin in the brain. This improves your mood, relieves anxiety, tension, and helps you sleep better. It has fewer side effects than older antidepressants. It usually takes 4-6 weeks for this medicine to work so you need to keep taking it even if you feel it is not working. Do not stop taking it, even if you feel better unless your doctor advises you to.

Side effects of Vortain Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Vortain
  • Constipation
  • Nausea
  • Vomiting

How to use Vortain Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Vortain 10 Tablet may be taken with or without food.

How Vortain Tablet works

Vortain 10 Tablet is a serotonin modulator and stimulator (SMS). It works by acting on multiple brain chemicals including serotonin, noradrenaline, dopamine, histamine, and acetylcholine which are thought to be involved in controlling mood and related mental processes.

Quick tips

  • Vortain 10 Tablet helps treat depression in adults.
  • It can be taken with or without food. However, take with food and/or at night to reduce nausea, diarrhea, or gas.
  • Take it at the same time each day to maintain a consistent level of medicine in your body.
  • It may take 8-12 weeks to see full effects. Keep taking it as prescribed. Your treatment may be continued for at least 6 months after the resolution of symptoms.
  • Your doctor may alter your dose based on your response to the medicine. Do not stop taking the medicine, even if you feel well.
  • Talk to your doctor if you experience sudden mood changes or unusual thoughts.

Safety advice

Alcohol

Alcohol

CAUTION
Alcohol should be used with caution while taking Vortain 10 Tablet.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Vortain 10 Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Vortain 10 Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Vortain 10 Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
You should exercise caution when driving or operating hazardous machinery especially on starting treatment with Vortain 10 Tablet or on changing the dose.
Kidney

Kidney

CAUTION
Vortain 10 Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Liver

Liver

CAUTION
Vortain 10 Tablet should be used with caution in patients with severe liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Vortain with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Life-threatening

Linezolid (Oral Route)

Do not consume Vortioxetine with Linezolid. If essential, watch out for symptoms such as flushing, increased blood pressure, weakness, or impaired coordination. Please consult your doctor.
Life-threatening

Linezolid (Injection Route)

Do not consume Vortioxetine with Linezolid. If essential, watch out for symptoms such as flushing, increased blood pressure, weakness, or impaired coordination. Please consult your doctor.
Life-threatening

Linezolid (Oral Route)

Do not consume Vortioxetine with Linezolid. If essential, watch out for symptoms such as flushing, increased blood pressure, weakness, or impaired coordination. Please consult your doctor.
Life-threatening

Linezolid (Oral Route)

Do not consume Vortioxetine with Linezolid. If essential, watch out for symptoms such as flushing, increased blood pressure, weakness, or impaired coordination. Please consult your doctor.
Life-threatening

Linezolid (Oral Route)

Do not consume Vortioxetine with Linezolid. If essential, watch out for symptoms such as flushing, increased blood pressure, weakness, or impaired coordination. Please consult your doctor.

Frequently asked questions

Vortain 10 Tablet belongs to a class of medicines known as serotonin modulator and simulator (SMS). It is used to treat depression. This medicine helps by acting on multiple brain chemicals including serotonin, noradrenaline, dopamine, histamine, and acetylcholine which are thought to be involved in controlling mood and related mental processes.
The most common side effects of Vortain 10 Tablet are nausea, vomiting and constipation. However, these usually resolve and are not bothersome, but if these side effects do not subside and worry you, you must consult your doctor as he/she may suggest ways to prevent or treat them.
Vortain 10 Tablet usually takes around 1-2 weeks to show improvement in the symptoms. Your sleep, appetite and energy levels are among the first physical symptoms to get better and hence signify that the medicine has started having its impact on you. However, remarkable benefits, such as those in your depression, may be seen after about 6-8 weeks of treatment.
Vortain 10 Tablet does not cause significant weight changes according to research reports. However, one study showed only 0.67 kgs of mean weight gain in some individuals who had been treated with Vortain 10 Tablet for a long term.
You should never stop taking Vortain 10 Tablet without discussing it with your doctor. If you stop taking Vortain 10 Tablet abruptly, you may have withdrawal symptoms such as irritability, nausea, dizziness, vomiting, nightmares, headache, and/or paresthesias (prickling, tingling sensation on the skin). Continue taking Vortain 10 Tablet for the duration as prescribed by your doctor to get maximum benefit. If you are not able to tolerate a dose or if you have completed your course of treatment, your doctor will reduce your dose gradually before taking you off this medicine completely.
Vortain 10 Tablet can be taken once a day either in the morning or at night. However, it is usually recommended to take Vortain 10 Tablet once a day in the morning since it can make you feel restless or keep you awake if taken late at night. You can take it with or without food. You should prefer taking it at the same time each day so that you remember to take it.

Fact Box

Chemical Class

Benzofuran derivative

Habit Forming

No

Therapeutic Class

NEURO CNS

Action Class

Serotonin modulator and stimulator
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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