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VALEra M 500 Tablet SR

Evogliptin (5mg)+ Metformin (500mg)

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VALEra M 500 Tablet SR is a combination of two medicines used to control high blood sugar levels in people with type 2 diabetes mellitus. This helps prevent serious complications of diabetes such as kidney damage, blindness, and may reduce your chance of having a heart attack or stroke.

Written By Dr. Syeda Aafia, MBA, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 21 Jul 2026 | 01:02 AM (IST)

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General Information

Contains

Evogliptin (5mg)+ Metformin (500mg)

Marketer

Alkem Laboratories Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

VALEra M 500 Tablet SR can be prescribed alone or together with other diabetes medications. All diabetes medicines work best when used along with a healthy diet and regular exercise. The dose you are given will depend on your condition, blood sugar levels, and what other medicines you are taking.

You should take it regularly and at the same time each day to get the most benefit from the medicine. Do not stop taking the medicine unless your doctor recommends it. It helps to control your blood sugar levels and helps prevent serious complications in the future. It is important to stay on the diet and exercise program recommended by your doctor while taking this medicine. Your lifestyle plays a big part in controlling diabetes.

Some common side effects of this medicine include diarrhea, nausea, vomiting, upset stomach, and headache. Low blood sugar level (hypoglycemia) is a possible side effect if you are also taking other diabetes medicines like insulin or sulfonylurea, so you need to know how to recognize and deal with it.

This medicine is not suitable for everyone. Before taking it, you should let your doctor know if you have ever had kidney, liver or heart disease, or problems with your pancreas. Pregnant or breastfeeding women should also consult their doctor before taking this medicine. Some other medicines can affect how this medicine works, so tell your doctor about all the medicines you are taking to make sure you are safe. You should try to avoid drinking alcohol as it lowers blood glucose. Your doctor will check your kidney function and blood sugar levels before and during treatment.

Uses of VALEra M Tablet SR

Treatment of Type 2 diabetes mellitus

Benefits of VALEra M Tablet SR

Treatment of Type 2 diabetes mellitus
VALEra M 500 Tablet SR is a medicine that helps to control high blood glucose (sugar) levels. It helps get rid of extra glucose from your body through urine. It also improves the body’s response to the hormone insulin, which is responsible for regulating blood glucose (sugar) levels in our body. The insulin helps to lower your blood glucose levels and prevents them from rising after taking meals. You should keep taking it for as long as it is prescribed.

Lowering blood glucose levels is an essential part of managing diabetes. If you can control the level you will reduce the risk of getting any of the serious complications of diabetes such as kidney damage, eye damage, nerve problems, and loss of limbs. Taking this medicine regularly along with proper diet and exercise will help you live a normal, healthy life.

Side effects of VALEra M Tablet SR

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of VALEra M

Diarrhea
Nausea
Vomiting
Upset stomach
Headache
Upper respiratory tract infection
Constipation
Flatulence
Heartburn
Dizziness
Taste change

How to use VALEra M Tablet SR

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. VALEra M 500 Tablet SR may be taken with or without food.

How VALEra M Tablet SR works

Evogliptin and Metformin are antidiabetic medications. Evogliptin works by increasing the release of insulin from the pancreas and decreasing the hormones that raise blood sugar levels. This reduces the fasting and post-meal sugar levels. Metformin works by lowering glucose production in the liver, delaying the absorption of sugar (glucose) from the intestines, and increasing the body's sensitivity to insulin.

Quick tips

VALEra M 500 Tablet SR is prescribed to control blood sugar and avoid long-term complications.
It may cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
Always carry some sugary food or fruit juice with you in case you experience hypoglycemia (low blood sugar) symptoms such as fatigue, dizziness, cold sweats, tremor, and anxiety.
It is important for you to take care of the skin on your lower limbs and to report any sores or signs of infection to your doctor.
Monitor your blood sugar regularly while taking this medicine.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with VALEra M 500 Tablet SR

Pregnancy

CONSULT YOUR DOCTOR

The safety of VALEra M 500 Tablet SR during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CONSULT YOUR DOCTOR

VALEra M 500 Tablet SR may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

CAUTION

VALEra M 500 Tablet SR may affect your driving ability if your blood sugar becomes too low or too high. Monitor your blood glucose and avoid driving if affected.

Kidney

CAUTION

VALEra M 500 Tablet SR should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

CAUTION

VALEra M 500 Tablet SR should be used with caution in patients with liver disease. Dose adjustment may be needed.

Frequently asked questions

What is VALEra M 500 Tablet SR used for?

VALEra M 500 Tablet SR is used to help control blood sugar in adults with type 2 diabetes when diet and exercise alone are not enough.

How long does it take to see improvements in blood sugar levels after starting VALEra M 500 Tablet SR?

The exact time VALEra M 500 Tablet SR takes to show improvement in blood sugar is not known. However, you may start noticing better blood sugar control within a few weeks, but full benefits usually come with continued use and lifestyle changes.

Is VALEra M 500 Tablet SR beneficial for weight management in diabetic patients?

VALEra M 500 Tablet SR is neutral to weight or may support modest weight management as it improves insulin sensitivity and sugar control.

Can VALEra M 500 Tablet SR help reduce the risk of diabetes complications?

By controlling blood sugar effectively, VALEra M 500 Tablet SR helps lower the risk of problems like nerve, kidney, or eye damage caused by diabetes.

Who should not take VALEra M 500 Tablet SR?

Individuals should not take VALEra M 500 Tablet SR if they have severe kidney or liver problems, metabolic acidosis (a buildup of acid in the blood), or if they are allergic to either evogliptin, metformin, or any other ingredients in the medicine.

Can VALEra M 500 Tablet SR cause serious side effects?

Although rare, serious side effects of VALEra M 500 Tablet SR may include lactic acidosis (a dangerous buildup of acid in the blood), severe allergic reactions, and issues affecting your pancreas or liver. Seek medical help immediately if you have symptoms like severe stomach pain, muscle pain, difficulty breathing, or swelling.

Are there risks related to kidney or liver problems during VALEra M 500 Tablet SR treatment?

Can VALEra M 500 Tablet SR cause low blood sugar?

VALEra M 500 Tablet SR usually does not cause low blood sugar on its own, but can if taken with other diabetes medicines like insulin. Watch for symptoms like sweating, shaking, dizziness, or confusion, and tell your doctor if they happen.

Fact Box

Habit Forming

Therapeutic Class

ANTI DIABETIC

Related lab tests

Glucose - Fasting Blood

Glucose - Postprandial Blood

Glycosylated Hemoglobin

References

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Alkem Laboratories Ltd
Address: Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver VALEra M 500 Tablet SR. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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VALEra M 500 Tablet SR

VALEra M 500 Tablet SR

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Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of VALEra M Tablet SR

Benefits of VALEra M Tablet SR

Side effects of VALEra M Tablet SR

How to use VALEra M Tablet SR

How VALEra M Tablet SR works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

What is VALEra M 500 Tablet SR used for?

How long does it take to see improvements in blood sugar levels after starting VALEra M 500 Tablet SR?

Is VALEra M 500 Tablet SR beneficial for weight management in diabetic patients?

Can VALEra M 500 Tablet SR help reduce the risk of diabetes complications?

Who should not take VALEra M 500 Tablet SR?

Can VALEra M 500 Tablet SR cause serious side effects?

Are there risks related to kidney or liver problems during VALEra M 500 Tablet SR treatment?

Can VALEra M 500 Tablet SR cause low blood sugar?

Fact Box

Habit Forming

Therapeutic Class

Related lab tests

Glucose - Fasting Blood

Glucose - Postprandial Blood

Glycosylated Hemoglobin

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

Related/Popular tests