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Uptonin Nasal Spray



Uptonin Nasal Spray is a medicine used for treatment of osteoporosis in postmenopausal women. It makes the bones stronger and lowers the risk of fractures.

Uptonin Nasal Spray should be used as you have been advised by your doctor. Normally you should blow your nose gently before using it, keep one nostril closed while applying the medicine into the other and then sniff hard to make sure it reaches deep into the nose. Then repeat for the other nostril. You should take adequate supplements of calcium and vitamin D while on the treatment of this medicine to make it more effective.

The most common side effects of this medicine include runny nose, nose bleed, back pain, joint pain, headache, and other nose symptoms such as itching, irritation, and discomfort. These are usually mild but if they bother you or do not go away, your doctor may be able to suggest ways of preventing or reducing them.

To make sure the medicine is safe for you, before taking this medicine, let your doctor know if you have any problems with your heart, kidneys, or liver. Pregnant and breastfeeding mothers should consult with their doctors before taking the medicine.

Uses of Uptonin Nasal Spray

Side effects of Uptonin Nasal Spray

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Uptonin

  • Runny nose
  • Nasal irritation

How to cope with side effects?

The occurrence of side effects varies from person to person. The following are a few ways of dealing with some of the common side effects. However, consult your doctor if these persist.

  • Coping with Nasal irritation
    Try using a saltwater nasal spray from time to time. Drink plenty of fluids to keep yourself hydrated and stop your nose drying out. Avoid things that irritate your nose (triggers such as pollen, dust and animal fur). Try not to blow or pick your nose as this may irritate it further. Inhale steam and use a humidifier to add moisture to the air in your home.

How to use Uptonin Nasal Spray

Use this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Insert the bottle tip into one nostril and close the other nostril. Direct the spray towards the sides of your nostril, away from the cartilage dividing the two sides of your nose. As you spray, breath gently and keep the head upright. Repeat the same process for the other nostrils.

Safety Advice

No interaction found/established
Uptonin Nasal Spray may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Uptonin Nasal Spray is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
No interaction found/established
No interaction found/established
No interaction found/established

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Uptonin Nasal Spray
₹275.0/ml of Nasal Spray
₹281.67/ml of Nasal Spray
2% costlier
₹324.29/ml of Nasal Spray
18% costlier
₹415.47/ml of Nasal Spray
51% costlier
Gemcal Nasal Spray
Alkem Laboratories Ltd
₹518.11/ml of Nasal Spray
88% costlier
Miacalcic Nasal 200
Novartis India Ltd
₹798/ml of Nasal Spray
190% costlier

Quick Tips

  • You have been prescribed Uptonin Nasal Spray to make your bones stronger, and lower the risk of fractures.
  • It is used in women with osteoporosis who have undergone menopause.
  • It may cause temporary dizziness. Don't drive or do anything requiring concentration until you know how it affects you.
  • Unopened bottles should be stored in the refrigerator. Once opened, they should be stored at room temperature for up to 35 days.
  • Stop using it and inform your doctor if you get any nosebleeds or notice any ulceration inside your nose.
  • Discontinue Uptonin Nasal Spray and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing.

Patient Concerns

She has osteoporosis should she take terifrac injections
Dr. Akshat Goel
Also ask the treating doctor about Zoledronic acid infusion and also about Calcinase nasal spray
Sir please can y tell a good nasal irigation medicine for sinus rinse I always suffer from post nasal drip thin mucus and sir is saline gel will be beneficial for me. Or I can try any methods for post nasal drip please advise I am suffering a lot due to post nasal drip all the time.
Dr. Shubhra Chandan Pradhan
Try flutiflo nasal spray
Do you have any questions related to Uptonin Nasal Spray ?

User Feedback


Q. Does Uptonin need to be refrigerated?

Yes, an unopened bottle of Uptonin need to be refrigerated. It should be kept at a temperature between 2°C and 8°C. Do not freeze. After opening the bottle of Uptonin, store it at room temperature between 15°C and 30°C.

Q. Does Uptonin increase bone density?

Uptonin contains calcitonin which is a hormone that is naturally produced by the thyroid gland and is responsible for maintaining calcium balance in the body. Uptonin decreases the bone loss and damage in patients with osteoporosis. In some cases, it also helps in bone formation by activating the bone forming cells, thereby increasing the bone density.

Q. Can Uptonin reduce the calcium levels in blood?

Yes, Uptonin can reduce the levels of calcium in the blood. If the calcium levels in your blood drop down severely then it can present with numbness or tingling in your fingers, toes, or around your mouth. The blood calcium levels need to be monitored in such cases. Immediately contact your doctor if you experience any such symptoms.

Q. How should I use Uptonin?

Follow the directions given by your prescriber and do ask him in case of any doubts. Usually, it is to be given in single nostril once daily. To start with we take 1 spray in left nostril on day 1, followed by right nostril on the second day. Continue to take the medicine inside the nose by switching nostrils every alternate day. Each bottle is set to deliver 30 doses. Do not use the bottle after 30 days.

Q. Is it fine to use Uptonin in pregnant women?

Generally, Uptonin is not recommended for pregnant women. However, enough evidence is not available to suggest risk associated with the use of Uptonin causing birth defects or miscarriage in pregnant women. Uptonin should be used in pregnant women with utmost caution. It is used only if the prescribing doctor finds potential benefit to be much larger than the risk involved.

Related Products


1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.


  1. Bikle DD. Agents That Affects Bone Mineral Homoestasis. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 758, 766.
  2. Friedman PA. Agents Affecting Mineral Ion Homeostasis and Bone Turnover. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1283-84, 1294.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 184-85.
  4. Calcitonin. [Accessed 02 Apr. 2019] (online) Available from:External Link
  5. Calcitonin. Spring Valley, New York: PAR PHARMACEUTICAL COMPANIES, INC.; 2014. [Accessed 02 Apr. 2019] (online) Available from:External Link
  6. Calcitonin. East Hanover, New Jersey: Novartis Pharmaceuticals Corporation; 2011. [Accessed 02 Apr. 2019] (online) Available from:External Link

Manufacturer/Marketer Address

Viilbery Healthcare Pvt. Ltd. Plot No. P- 64, Milap Nagar, M. I. D. C Residential Zone Near AIMS Hospital, Dombivili, East, Thane - 421 203, Maharashtra, India.
A licensed vendor partner from your nearest location will deliver Uptonin Nasal Spray. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
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