Unicalcin 50IU Injection is a medicine used in the treatment of postmenopausal osteoporosis. It makes the bones stronger and lowers the risk of fractures. It may also be used to treat Paget’s disease of bone and to quickly reduce calcium levels in the blood.
Unicalcin 50IU Injection is given by a healthcare professional and should not be self-administered. You should use it regularly and at the same time each day to get the maximum benefit from it. Continue using it as recommended by your doctor and complete the dose even if you feel better. If you stop, your symptoms may get worse.
Some common side effects of this medicine include injection site reactions, flushing, skin rash, fatigue, edema, musculoskeletal pain, joints pain, high blood pressure, vomiting, abdominal pain, diarrhea, dizziness, headache, and visual disturbance. Talk to your doctor if any of these side effects do not go away with time or get worse. Your doctor may help with ways to reduce or prevent these symptoms.
To make sure the medicine is safe for you, before taking this medicine, let your doctor know if you have any problems with your heart, kidneys, or liver. Pregnant and breastfeeding mothers should consult with their doctors before taking the medicine.
Calcium is a mineral found in different places in your body and has many functions including bone growth. Most of your calcium should be in your bones. When you have more calcium in your blood than normal it is called hypercalcemia. Unicalcin 50IU Injection reduces the amount of calcium in your blood. Being immobile makes hypercalcemia worse. Whenever possible you should take regular exercise, especially weight-bearing exercise. Do not take calcium or vitamin D3 supplements and try to decrease your intake of these in your diet.
Side effects of Unicalcin Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Unicalcin
Flushing (sense of warmth in the face, ears, neck and trunk)
High blood pressure
Joint pain
Vomiting
Dizziness
Visual disturbance
Edema (swelling)
Skin rash
Abdominal pain
Diarrhea
Musculoskeletal (bone, muscle or joint) pain
Injection site reactions (pain, swelling, redness)
Fatigue
Headache
How to use Unicalcin Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Unicalcin Injection works
Unicalcin 50IU Injection is a calcitonin receptor agonist. It acts by suppressing the activity of osteoclasts, cells that cause destruction of bone, thereby strengthening the bones and minimizing the risk of fractures.
Safety advice
Alcohol
CAUTION
Caution is advised when consuming alcohol with Unicalcin 50IU Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Unicalcin 50IU Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Unicalcin 50IU Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
CONSULT YOUR DOCTOR
It is not known whether Unicalcin 50IU Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
CAUTION
Unicalcin 50IU Injection should be used with caution in patients with severe kidney disease. Dose adjustment of Unicalcin 50IU Injection may be needed. Please consult your doctor.
Liver
SAFE IF PRESCRIBED
Unicalcin 50IU Injection is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Unicalcin 50IU Injection may not be needed in these patients. Please consult your doctor.
What if you forget to take Unicalcin Injection?
If you miss a dose of Unicalcin 50IU Injection, consult your doctor.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine
Quick tips
You have been prescribed Unicalcin 50IU Injection for short term treatment of paget’s disease, high calcium levels in the blood, and to prevent bone loss in postmenopausal osteoporosis.
Treatment is usually done for the shortest possible time with the lowest possible dose.
It may cause dizziness, fatigue and blurring of vision. Don't drive or do anything requiring concentration until you know how it affects you.
Discontinue Unicalcin 50IU Injection and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing.
Fact Box
Chemical Class
Hormones
Habit Forming
No
Therapeutic Class
PAIN ANALGESICS
Action Class
Bone Resorption Inhibitors- Calcitonin
Patient concerns
Hi doc, my mom is suffering from right knee pain from past 2yrs. Every thing seems to be normal in x-ray. Want to seek second opinion whether to use UNICALCIN NASAL SPRAY
Vipul Aggarwal
Osteoarthritis is the most common reasonI need to see the X-raysI won't prefer nasal sprayBetter to get dexa scan done and if it's osteoporosis then start with bisphosponates / teriparatide. They are better
I am very tensed . My parathyroid hormone is very high . PTH - 110.4 . Please help me and suggest me proper medicines . Please advice me as soon as possible . I am also facing respiratory problems , for that i am consulting a doctor but for PTH please help me .
Dr. Sanjay Bhatt
Physician
In primary hyperparathyroidism, an enlargement of one or more of the parathyroid glands causes overproduction of the hormone, resulting in high levels of calcium in the blood (hypercalcemia), which can cause a variety of health problems. Surgery is the most common treatment for primary hyperparathyroidism
I am diabetic, also osteoporosis. Which diagnostic test will show my current status
Dr. Anshul Varshney
Physician
Hello, Welcome to 1mg. I am Anshul Varshney for your help. For Osteoporosis, you may go for Bone Mineral Density testing, 25-Hydroxy Vitamin D3 levels, Serum Calcium levels.
High TSH, Hyperkalemia, Hypercalcemia, Vitamin D deficiency, B12 deficiency. Blood report attached. Please suggest medicines.
Dr. Sfurti Mann
Internal Medicine
No medicine required for suna clinical hypothyroid at present Repeat TSH after 6 weeks alongwith anti TPO antibody Drink plenty of fluids for the urinary abnormalities Take calcirol sachet once weekly with milk for three months Visit a physician personally for detailed consultation Take diet from a qualified dietician as cholesterol is high
A person can control his or her sugar levels by regular exercise and walk or regular aerobic exercises at least 30 to 45 minutes per day.MEDICAL NUTRITIONAL THERAPY THAT IS TO MAINTAIN CALORIES INTAKE AS PER BMI .TAKE HELP OF DIABETIC EDUCATOR. VISIT YOU DOCTOR AND LOW ALL WHAT DOCTOR SUGGESTED.IN TIME ALL ROUTINE INVESTIGATIONS SHOULD BE DONE.you souls not treat it as disease but start of a healthy life.Uncontrolled sugar levels for long time leads to lower limb weakness which is neuropathy and which is followed by foot ulcers and other complications.online prescription is not allowed without seeing pt.so contact doctor nearby for any change or dose adjustment or visit my clinic at gurgaon sector 52 RdCity snergy multi speciality clinic near SRS MARKET
How long should you take Unicalcin 50IU Injection?
The duration of therapy will depend on the response of the patient towards the therapy and side effects if any encountered during the therapy. Unicalcin 50IU Injection is usually prescribed for a long period in diseases of bone. However, the need for a long and continued therapy has to be assessed from time to time. This is because there are chances of cancer on long-term administration of this medicine.
Does Unicalcin 50IU Injection build bone?
Unicalcin 50IU Injection contains calcitonin which is a hormone that regulates the calcium level in the blood. This hormone helps the body to reverse bone loss and sometimes also helps in bone formation. Due to this, the number of cells that damage bones becomes comparatively less, hence the bone damage is halted. It has been observed that using Unicalcin 50IU Injection can initially increase bone formation by mild activation of the bone-forming cells.
What is the difference between calcitriol and Unicalcin 50IU Injection?
Calcitriol is the active form of vitamin D and is produced in the kidneys. Calcitriol is also given as a supplement and helps in calcium metabolism in our body. The prime role of calcitriol is to increase the absorption of calcium from the gut, decrease its excretion from the kidneys, and increased deposition of calcium in bones, thereby helping in the maintenance of normal bone health. Whereas, Unicalcin 50IU Injection contains calcitonin which is a hormone that regulates blood calcium levels by excreting the extra calcium from the blood through urine. Both the hormone helps in maintaining the calcium balance in our body.
Does Unicalcin 50IU Injection help with pain?
Unicalcin 50IU Injection is not an analgesic medication that reduces the pain directly. Patients with osteoporosis experience pain in the bone as a common symptom. Unicalcin 50IU Injection is used in osteoporosis for the prevention of bone loss and damage which will indirectly lead to a decrease in the pain perceived by the individual. There are some reports of partial analgesic activity of Unicalcin 50IU Injection, but the fact is yet to be established.
Should I follow any special dietary instructions or take dietary supplements along with Unicalcin 50IU Injection?
Yes, it is recommended to take an adequate amount of calcium-containing food while you are prescribed Unicalcin 50IU Injection for the treatment of osteoporosis. Also, your prescribing physician may ask you to take calcium and vitamin D supplements if your dietary intake is not enough.
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References
Bikle DD. Agents That Affects Bone Mineral Homoestasis. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 758, 766.
Friedman PA. Agents Affecting Mineral Ion Homeostasis and Bone Turnover. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1283-84, 1294.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 184-85.