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MD (Pharmacology), MBBS
Last updated:
24 Dec 2019 | 03:54 PM (IST)
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Twichek Plus 75 mg/40 mg Capsule SR


Overview

Introduction

Twichek Plus 75 mg/40 mg Capsule SR is a prescription medicine which is used in the treatment of gastroesophageal reflux disease (acid reflux), intestinal ulcers, and irritable bowel syndrome. It reduces excess acid production in the stomach and prevents the reflux of stomach acid into the food pipe.

Twichek Plus 75 mg/40 mg Capsule SR is taken with or without food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine.

The most common side effects are nausea, stomach pain, diarrhea, flatulence, constipation, headache, weakness, and flu-like symptoms. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. It may also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your sleepiness.

Lifestyle modifications like having fiber-rich diet, avoiding foods that trigger your symptoms, increasing fluid intake and regular exercise can help you to get better results. Before taking it, you should tell your doctor if you have any kidney or liver diseases. You should also tell your doctor if you are pregnant, planning pregnancy or breastfeeding.

Side effects of Twichek Plus Capsule SR

Common
  • Nausea
  • Stomach pain
  • Diarrhea
  • Flatulence
  • Constipation
  • Headache
  • Dizziness
  • Weakness
  • Sleepiness
  • Flu-like symptoms

How to use Twichek Plus Capsule SR

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Twichek Plus 75 mg/40 mg Capsule SR is to be taken empty stomach.

How Twichek Plus Capsule SR works

Twichek Plus 75 mg/40 mg Capsule SR is a combination of two medicines: Levosulpiride and Rabeprazole. Levosulpiride is a prokinetic which works by increasing the release of acetylcholine (a chemical messenger). This increases the movement of stomach and intestines, and prevents reflux (acid going up to the food pipe). Rabeprazole is a proton pump inhibitor (PPI). It works by reducing the amount of acid in the stomach which helps in the relief of acid-related indigestion and ulcers.

Safety Advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Twichek Plus 75 mg/40 mg Capsule SR.
Pregnancy
CONSULT YOUR DOCTOR
Twichek Plus 75 mg/40 mg Capsule SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breastfeeding
CONSULT YOUR DOCTOR
Information regarding the use of Twichek Plus 75 mg/40 mg Capsule SR during breastfeeding is not available. Please consult your doctor.
Driving
UNSAFE
Twichek Plus 75 mg/40 mg Capsule SR may cause side effects which could affect your ability to drive.
Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Twichek Plus 75 mg/40 mg Capsule SR in patients with kidney disease. Please consult your doctor.
However, limited data suggest a cautious use of this medicine in these patients.
Liver
CAUTION
Twichek Plus 75 mg/40 mg Capsule SR should be used with caution in patients with severe liver disease. Dose adjustment of Twichek Plus 75 mg/40 mg Capsule SR may be needed. Please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Twichek Plus 75 mg/40 mg Capsule SR
₹19.8/Capsule SR
Rabonik 40 Plus Capsule SR
Eris Lifesciences Ltd
₹21.78/Capsule SR
10% costlier
₹23.98/Capsule SR
21% costlier
Mac Rabonik Plus Capsule SR
Eris Lifesciences Ltd
₹21.78/Capsule SR
10% costlier

Quick Tips

  • It is a well-tolerated medicine and provides relief for a long time.
  • Take it one hour before the meal, preferably in the morning.
  • Inform your doctor if you get watery diarrhea, fever, or stomach pain that does not go away.
  • Do not consume alcohol while taking Twichek Plus 75 mg/40 mg Capsule SR as it can increase the risk of stomach damage.
  • Long-term use may cause weak or broken bones. Take adequate intake of dietary calcium and vitamin D or their supplements. Do not take Twichek Plus 75 mg/40 mg Capsule SR for longer than prescribed.

Patient Concerns

arrow
Heartburn Mental disorder Depression Frequent persistent heartburn Gastroesophageal reflux disease Irritable bowel syndrome Indigestion Back flow of acid from stomach Difficulty in swallowing Inflammation of esophagus Excess acid secretion by stomach Intestinal or stomach ulcers
Dr. Sunil Sekhri
Diabetology
You need to be examined in clinic to reach a diagnosis and then appropriate medicine can be prescribed
Restless leg syndrome with irritable bowel syndrome
Dr. Pushkar Mani
Physician
take cobadex czs once daily for 1 monthevion 400 mg once daily for 1 month
arrow
Do you have any questions related to Twichek Plus 75 mg/40 mg Capsule SR ?

User Feedback


FAQs

Q. Which is the best time to take Twichek Plus?

Take the Twichek Plus exactly as directed by your doctor. It is best to take one capsule daily on an empty stomach.

Q. What are the contraindications associated with the use of Twichek Plus?

Use of Twichek Plus should be avoided in patients with known allergy to any of the components or excipients of this medicine.

Q. Can the use of Twichek Plus cause dizziness?

Yes, the use of Twichek Plus can cause dizziness (feeling faint, weak, unsteady or lightheaded) in some patients. If you feel dizzy or lightheaded, it is better to rest for sometime and resume once you feel better.

Q. Does the use of Twichek Plus lead to increased risk of fractures?

Several studies in adults suggest that treatment with Twichek Plus may be associated with an increased risk of osteoporosis-related fractures of the hip, wrist or spine. The risk of fracture was increased in patients who received high dose. High dose can mean multiple daily doses, and long-term therapy (a year or longer).

Q. Can I drive while taking Twichek Plus?

No, taking Twichek Plus may make you feel sleepy, dizzy or could affect your eyesight. So do not drive or use machines until you know how this medicine affects you.

Q. What are the instructions for the storage and disposal of Twichek Plus?

Keep this medicine in the packet or the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

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Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Levosulpiride. Limassol, Cyprus: Medochenie Ltd.; 2015. [Accessed 12 Apr. 2019] (online) Available from:External Link
  2. Rabeprazole. Charlotte, North Carolina: FSC Laboratories; 1999 [revised Dec. 2014]. [Accessed 12 Apr. 2019] (online) Available from:External Link
  3. ScienceDirect. Levosulpiride. [Accessed 12 Apr. 2019] (online) Available from:External Link
  4. Drugs.com. Rabeprazole. [Accessed 12 Apr. 2019] (online) Available from:External Link
Manufacturer/Marketer Address
8th Floor, Commerce House IV, Prahladnagar, Ahmedabad – 380015 Gujarat, India
A licensed pharmacy from your nearest location will deliver Twichek Plus 75 mg/40 mg Capsule SR. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your prescription and the availability of this medicine.
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