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30 Dec 2019 | 06:24 PM (IST)
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Ttino 0.025% Cream

Prescription Required



Ttino 0.025% Cream belongs to a group of medicines known as retinoids that are used to treat severe acne, which occur as pimples, in adults and adolescents from 12 years of age only after puberty. This medicine is for patients whose acne has not responded to other treatments.

Ttino 0.025% Cream reduces excessive oil production of the skin. Ideally, a pinpoint application at night time is recommended for a duration as prescribed by the doctor. The amount you need, and how long you take it will depend on what you are being treated for. You should normally wash and dry the affected area before applying a thin layer of gel or cream usually once a day at bedtime. Follow your doctor’s instructions. You should not apply it to damaged or broken skin and avoid contact with your mouth, eyes and nose. It may take several weeks for your symptoms to improve but keep using it regularly to get the most benefit. If you notice no improvement after a few weeks, see your doctor again. Using more medicine or applying it more often than prescribed will not make it work any faster and may increase side effects.

The most common side effects include itching, stinging, peeling and redness of the skin. They are not usually serious and often disappear after getting used to the cream but, if they bother you or do not go away, tell your doctor. You may need to apply smaller amounts or use it less often. Serious side effects are rare.

Ttino 0.025% Cream may make you more sensitive to sunlight so you should limit exposure to the sun if possible. Drink plenty of water and use moisturizer as it may lead to dryness of the mouth, lips and eyes. It may make your skin more fragile. It is advised, not to have any waxing (hair removal), or laser treatments during treatment. This medicine may lead to birth defects, do consult your doctor if you are pregnant or planning to get pregnant.

Uses of Ttino Cream

Side effects of Ttino Cream

  • Application site reactions (burning, irritation, itching and redness)
  • Dry skin
  • Anemia (low number of red blood cells)
  • Cracked lips
  • Eyelid inflammation
  • Increased liver enzymes
  • Rash
  • Skin peeling
  • Cracking of skin

How to use Ttino Cream

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the cream. Wash your hands after applying, unless hands are the affected area.

How Ttino Cream works

Ttino 0.025% Cream is a derivative of vitamin A. It acts on glands (sebaceous) on your skin to reduce the production of a natural substance (sebum) that causes acne. Also, the controlled sebum production kills acne-causing bacteria. It also works as an anti-inflammatory to decrease inflammation (redness and swelling).

Safety Advice

No interaction found/established
Ttino 0.025% Cream is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Ttino 0.025% Cream is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
No interaction found/established
No interaction found/established
No interaction found/established

What if you forget to take Ttino Cream?

If you miss a dose of Ttino 0.025% Cream, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
No alternate brands found for this medicine

Quick Tips

  • You have been prescribed Ttino 0.025% Cream for the treatment of acne.
  • Clean the area to be treated with water and a non-medicated soap, and let it dry for 20-30 minutes before applying Ttino 0.025% Cream.
  • It may increase the severity of the lesions in the first few weeks of use. Continue using it as prescribed by your doctor.
  • It may cause stinging sensation or a feeling of warmth when you first start using it. Inform your doctor if this persists.
  • Avoid exposure to sunlight while using it as it increases the sensitivity of your skin. Use protective measures such as sun-cream or protective clothing.
  • Avoid face waxing and laser treatment while using this medicine as it makes your skin more fragile.
  • Do not use Ttino 0.025% Cream if you are pregnant or breastfeeding.
  • Inform your doctor if excessive skin dryness or skin sensitivity take place.

Patient Concerns

I have dark sports on my face due to acne and also malesma on sides of my cheek how to get rid
Dr. Atul Jain
apply retino A 0.025% cream at night over dark spot at night for 1 hour
Marks and whitish acne type sympton on hand
Dr. Souvik Sardar
Mix tretin (0.025%) cream with olesoft cream in 1:1 ratio - apply daily in the evening for 4-5hrs and then wash off at bedtime apply only olesoft cream Dnt premix them and store
Do you have any questions related to Ttino 0.025% Cream ?

User Feedback


Q. What are the precautions that I should follow while using Ttino?

Contact with mouth, eyes, lips, mucous membranes (such as inside of mouth) and wounded skin should be avoided. In case of accidental contact, rinse well with water. Care should be taken not to let the medicine accumulate in skin folds. As Ttino may cause increased sensitivity to sunlight, deliberate or prolonged exposure to sunlight or sunlamps should be avoided or minimized. If sun exposure cannot be avoided, use sunscreen.

Q. I just had a cosmetic treatment. Can I use Ttino on that part of the skin?

Don’t use Ttino on skin that has recently had cosmetic treatment such as depilation, chemical hair treatment, chemical peel, dermabrasion or laser resurfacing. You should allow your skin to heal after any treatment before using Ttino.

Q. I have stopped using Ttino. Can I now plan my pregnancy?

You should wait for about 1 month after stopping Ttino before you plan your pregnancy as it can harm your unborn baby.

Q. Can Ttino be used in children?

Ttino gel is for teenagers and adults with mild to moderate acne. Do not give Ttino gel to children before puberty or under the age of 12.

Q. What if I use too much of Ttino?

If you use too much Ttino gel or use it more often than recommended, it may make your skin red or irritated. If this happens, use the gel less often or stop using it for a few days.

Q. Can I donate blood while using Ttino?

Do not donate blood while using Ttino gel and for at least 1 month after stopping it. If your blood is given to a pregnant woman, it may harm her unborn baby.

Q. What are the long-term side effects of Ttino?

A normal course of treatment of Ttino is 15–20 weeks. Therefore, long-term effects in low doses have not been studied. However, it may have some effect on the bone mineral density. It may decrease bone mineral density in some patients, resulting in osteoporosis or fractures.

Q. How do I use Ttino on my face?

Always wash and dry your skin, and completely remove any make-up before applying the gel. Use your fingertips to apply a thin layer of the gel on the areas affected with acne. Apply it to all areas of skin that have acne and not just each spot. Try not to use too much, especially where the gel could run into your eyes or build up in folds of skin. Using more gel will not make your spots clear up more quickly. Do not use Ttino gel on irritated areas of skin, for example, cuts, burns or sunburn as it can make the irritation worse.

Q. How long does it take for Ttino to start working?

The acne may get worse at the beginning of the treatment with Ttino gel. But, it normally improves after 6 to 8 weeks.

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Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
  1. Robertson DB, Maibach HI. Dermatologic Pharmacology. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 1056.
  2. Burkhart C, Morrell D, Goldsmith L. Dermatological Pharmacology. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1812.
  3. Sardana K, Madan A. How to Treat Acne. Sardana K, editor. In: Clinical Approach to Acne Vulgaris. 1st ed. New Delhi: CBS Publishers & Distributors Pvt. Ltd.; 2015. pp. 64-67.
  4. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 745-47.
  5. ScienceDirect. Isotretinoin. [Accessed 03 Apr. 2019] (online) Available from:External Link
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 03 Apr. 2019] (online) Available from:External Link
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