Trubose-Plus Tablet

Nateglinide (60mg)+ Metformin (500mg)+ Voglibose (0.2mg)

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Trubose-Plus Tablet is a medicine used in the treatment of type 2 diabetes mellitus. It helps in controlling blood sugar level in people with type 2 diabetes mellitus. It should be used along with a proper diet and exercise for best results.

Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 08 May 2026 | 03:58 PM (IST)

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General Information

Contains

Nateglinide (60mg)+ Metformin (500mg)+ Voglibose (0.2mg)

Marketer

AAR ESS Remedies Pvt Ltd

The content is shown in English

Product introduction

Trubose-Plus Tablet should be taken with food. Keep taking this medicine, even if you feel your blood sugar levels are controlled. If you stop it without consulting your doctor, your blood sugar levels could rise and put you at risk of complications. You should remember that it is only part of a treatment program that should also include a healthy diet, regular exercise, and weight reduction as advised by your doctor. Your lifestyle plays a big part in controlling diabetes.

The most common side effects of this medicine include nausea, fatigue, dizziness, vomiting, and headache. To prevent this, it is important to have regular meals and always carry a fast-acting source of glucose such as sugary food or fruit juice with you. Drinking alcohol can also increase your risk of low blood sugar levels and should be avoided. If you experience any other symptoms which you think is caused by this medicine, you should let your doctor know.

You should not take it if you have type 1 diabetes mellitus, if you have diabetic ketoacidosis (high levels of acid in your blood), or if you have severe kidney or liver disease. Pregnant or breastfeeding women should also consult their doctor before taking it. Your blood sugar levels should be checked regularly and your doctor may also advise blood tests to monitor your blood cell counts and liver function.

Uses of Trubose Tablet

Treatment of Type 2 diabetes mellitus

Benefits of Trubose Tablet

Treatment of Type 2 diabetes mellitus
Trubose-Plus Tablet is a medicine that helps to control high blood glucose (sugar) levels. It helps get rid of extra glucose from your body through urine. It also improves the body’s response to the hormone insulin, which is responsible for regulating blood glucose (sugar) levels in our body. The insulin helps to lower your blood glucose levels and prevents them from rising after taking meals. You should keep taking it for as long as it is prescribed.

Lowering blood glucose levels is an essential part of managing diabetes. If you can control the level you will reduce the risk of getting any of the serious complications of diabetes such as kidney damage, eye damage, nerve problems, and loss of limbs. Taking this medicine regularly along with proper diet and exercise will help you live a normal, healthy life.

Side effects of Trubose Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Trubose

Dizziness
Nausea
Vomiting
Fatigue
Headache

How to use Trubose Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Trubose-Plus Tablet may be taken with or without food.

How Trubose Tablet works

Trubose-Plus Tablet is a combination of three anti-diabetic medicines: Nateglinide, Metformin, and Voglibose, that act in different ways. Nateglinide increases the amount of insulin released by the pancreas which prevents blood glucose from rising very high after meals. Metformin, on the other hand, works by lowering glucose production in the liver, delaying the absorption of sugar (glucose) from the intestines, and increasing the body's sensitivity to insulin. Voglibose inhibits the intestinal enzymes responsible for breaking complex sugars into simple sugars such as glucose. This prevents blood glucose levels from rising very high immediately after meals.

Quick tips

Trubose-Plus Tablet is prescribed to control blood sugar and avoid long-term complications.
Take it after you have eaten a meal or with a snack, as this will reduce the chance of an upset stomach.
It may cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
Always carry some sugary food or fruit juice with you in case you experience hypoglycemia (low blood sugar) symptoms such as fatigue, dizziness, cold sweats, tremor, and anxiety.
It is important for you to take care of the skin on your lower limbs and to report any sores or signs of infection to your doctor.
Monitor your blood sugar regularly while taking this medicine.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Trubose-Plus Tablet

Pregnancy

UNSAFE

Trubose-Plus Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.

Breast feeding

CONSULT YOUR DOCTOR

Trubose-Plus Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

UNSAFE

Trubose-Plus Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Trubose-Plus Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.

Liver

UNSAFE

Trubose-Plus Tablet is unsafe to use in patients with liver disease and should be avoided.

Frequently asked questions

What is Trubose-Plus Tablet used for?

Trubose-Plus Tablet is used to treat type 2 diabetes mellitus. It helps control blood sugar levels and should be taken along with a healthy diet and regular exercise for the best results.

Can Trubose-Plus Tablet help prevent long-term complications of diabetes?

Yes, by maintaining blood sugar within target ranges, Trubose-Plus Tablet helps reduce risks of diabetes-related problems like nerve, kidney, or eye damage.

How soon can I expect to see improvements in my blood sugar levels after taking Trubose-Plus Tablet?

The exact time Trubose-Plus Tablet takes to control blood sugar levels is not known. However, many people notice better control of after-meal sugar spikes within a few days to weeks of starting the medicine.

Can Trubose-Plus Tablet replace lifestyle changes like diet and exercise?

No. Trubose-Plus Tablet works best combined with healthy eating, regular physical activity, and weight management as advised by your doctor.

Are there specific times to take Trubose-Plus Tablet for the best effect?

Usually, Trubose-Plus Tablet is taken before meals to maximize control of blood sugar spikes after eating. Always follow your doctor’s instructions on timing.

What should I do if my blood sugar does not improve after taking Trubose-Plus Tablet?

Trubose-Plus Tablet may take a few days to control the blood sugar levels. Even after that, if you are unsure about no change in blood sugar level, consult your doctor. They might check your dosage, adherence, diet, or consider additional treatments.

Can I take Trubose-Plus Tablet if I experience low blood sugar symptoms?

While Trubose-Plus Tablet has a low risk of low blood sugar, if symptoms occur, seek medical advice promptly and discuss with your doctor about managing such risks.

Fact Box

Habit Forming

Therapeutic Class

ANTI DIABETIC

Related lab tests

Glucose - Fasting Blood

Glucose - Postprandial Blood

Glycosylated Hemoglobin

References

Buse JB, Tan MH, Prince MJ, et al. The effects of oral anti-hyperglycaemic medications on serum lipid profiles in patients with type 2 diabetes. Diabetes Obes Metab. 2004 Mar;6(2):133-56. [Accessed 29 Dec. 2025]. Available from:

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: AAR ESS Remedies Pvt Ltd
Address: Aar Ess Remedies Private Limited, C-28, Sector-65, Noida-201301, Uttar Pradesh, India

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Trubose-Plus Tablet

Save more with additional offers

General Information

Contains

Marketer

Product introduction

Uses of Trubose Tablet

Benefits of Trubose Tablet

Side effects of Trubose Tablet

How to use Trubose Tablet

How Trubose Tablet works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

What is Trubose-Plus Tablet used for?

Can Trubose-Plus Tablet help prevent long-term complications of diabetes?

How soon can I expect to see improvements in my blood sugar levels after taking Trubose-Plus Tablet?

Can Trubose-Plus Tablet replace lifestyle changes like diet and exercise?

Are there specific times to take Trubose-Plus Tablet for the best effect?

What should I do if my blood sugar does not improve after taking Trubose-Plus Tablet?

Can I take Trubose-Plus Tablet if I experience low blood sugar symptoms?

Fact Box

Habit Forming

Therapeutic Class

Related lab tests

Glucose - Fasting Blood

Glucose - Postprandial Blood

Glycosylated Hemoglobin

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests