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Trixide-H Tablet

Written By Dr. Subita Alagh, BDS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 25 Nov 2025 | 03:07 PM (IST)
Trixide-H Tablet is a combination of two medicines. It is used in the treatment of depression associated with anxiety. It helps in regulating mood and to reduce anxiety.
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General Information

Contains

Amitriptyline (12.5mg)+ Chlordiazepoxide (5mg)

Marketer

Talent India

Storage

Store below 30°C
The content is shown in English
Trixide-H Tablet image
Trixide-H Tablet image

Product introduction

Trixide-H Tablet is taken with or without food. However, it is advised to take it at a fixed time each day to maintain a consistent level of medicine in the blood. In case you miss a dose of this medicine, take it as soon as you remember. Never skip any dose and finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to the doctor as it may worsen your symptoms. Taking this medicine for a long time may require regular monitoring of blood and liver functions.

Some common side effects of this medicine include constipation, difficulty in urination, weight gain, confusion, orthostatic hypotension (sudden lowering of blood pressure on standing). This medicine may cause weight loss. In case of losing weight, consult a dietitian for dietary supplements or try to increase your food portion. Most of the common side effects tend to be mild. Your doctor may be able to suggest ways of preventing or reducing side effects if they bother you or do not go away. Serious side effects are rare. Remember to inform your doctor if you develop any unusual changes in mood as it may lead to suicidal thoughts.

Take caution while taking medicine if you are suffering from liver disease. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Uses of Trixide-H Tablet

Benefits of Trixide-H Tablet

Treatment of Depression
Trixide-H Tablet works by affecting the balance of certain chemicals (such as serotonin) in the brain. It helps improve mood and feelings of wellbeing, relieve anxiety and tension, helps you sleep better, and increase your energy level. It is an effective antidepressant but may cause drowsiness. You need to take it regularly as it is prescribed for it to be most effective and should not stop taking it suddenly.

Side effects of Trixide-H Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Trixide-H
  • Constipation
  • Difficulty in urination
  • Weight gain
  • Confusion
  • Orthostatic hypotension (sudden lowering of blood pressure on standing)
  • Tiredness
  • Blurred vision
  • Dryness in mouth
  • Increased heart rate
  • Uncoordinated body movements
  • Depression
  • Memory impairment

How to use Trixide-H Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Trixide-H Tablet may be taken with or without food.

How Trixide-H Tablet works

Trixide-H Tablet is a combination of two medicines:.

Quick tips

  • Trixide-H Tablet is prescribed for the treatment of depression.
  • It can take a week or two after starting this treatment before the effect begins to build up, and 4-6 weeks before you feel the full benefit. Do not stop taking it after a week or two, feeling it is not helping.
  • Do not stop taking Trixide-H Tablet unless your doctor tells you to do so. Stopping treatment suddenly can cause problems and your doctor will probably want you to reduce your dose gradually when this becomes necessary.
  • Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress.
  • Inform your doctor if you are taking any other antidepressants.
  • Inform your doctor immediately if you get thoughts about harming yourself or ending your life.
  • Avoid alcohol while taking Trixide-H Tablet.
  • If you have diabetes, you will be asked to monitor your blood glucose level regularly as Trixide-H Tablet may affect the levels of sugar in your blood.
  • Trixide-H Tablet is prescribed for the treatment of depression.
  • It can take a week or two after starting this treatment before the effect begins to build up, and 4-6 weeks before you feel the full benefit. Do not stop taking it after a week or two, feeling it is not helping.
  • Do not stop taking Trixide-H Tablet unless your doctor tells you to do so. Stopping treatment suddenly can cause problems and your doctor will probably want you to reduce your dose gradually when this becomes necessary.
  • Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress.
  • Inform your doctor if you are taking any other antidepressants.
  • Inform your doctor immediately if you get thoughts about harming yourself or ending your life.
  • Avoid alcohol while taking Trixide-H Tablet.
  • If you have diabetes, you will be asked to monitor your blood glucose level regularly as Trixide-H Tablet may affect the levels of sugar in your blood.

Safety advice

Alcohol

Alcohol

UNSAFE
It is unsafe to consume alcohol with Trixide-H Tablet
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Trixide-H Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Trixide-H Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

UNSAFE
Trixide-H Tablet may cause side effects that could affect your ability to drive.
As Trixide-H Tablet may make you feel drowsy or affect your concentration and this may affect your ability to drive.
Kidney

Kidney

SAFE IF PRESCRIBED
Trixide-H Tablet is probably safe to use in patients with kidney disease. Limited data suggest dose adjustment may not be needed.
Liver

Liver

CAUTION
Trixide-H Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.

Frequently asked questions

During the first few months of treatment, Trixide-H Tablet may increase suicidal thoughts or actions in some patients. Patients having mood or behavioral disorder have a high risk of developing suicidal thoughts and actions. You should pay close attention and report your doctor of any such behavior or mood changes. Make sure that you visit the doctor for the scheduled follow-up appointments.
No, you should continue to take Trixide-H Tablet, even if you feel well. If you stop Trixide-H Tablet suddenly, serious withdrawal symptoms may occur. Consult your doctor if the symptoms are relieved, he might decrease your dose gradually.
There are reports which suggest that the use of Trixide-H Tablet can cause weight gain. If you maintain good eating habits and exercise regularly, you might not gain any weight. An important to remember is that it is easier to prevent weight gain than losing increased weight.
Yes, Trixide-H Tablet can make you feel sleepy. Avoid driving, operating machinery, working at heights or participating in potentially dangerous activities till you know how this medicine affects you.
The use of Trixide-H Tablet can affect the sexual life of both men and women. Most commonly caused problems are decreased sexual desire, erectile dysfunction (inability to develop or maintain erection during the sexual activity) and inability to reach orgasm. It can also cause a decrease in satisfaction and cause discomfort while having sex. If you experience these problems, discuss with your doctor.
No, do not drink alcohol while you are taking Trixide-H Tablet. Drinking alcohol can increase the severity of drowsiness or sleepiness caused by Trixide-H Tablet.
Yes, Trixide-H Tablet can the change the color of the urine to blue or green. This change of color is expected while using Trixide-H Tablet, and it is not harmful. Your urine color becomes normal once you stop taking Trixide-H Tablet.
Everybody responds differently to the treatment. In general, it can take several weeks to feel the full benefits of Trixide-H Tablet, although some people will start to feel better sooner. When taking Trixide-H Tablet, it is important to give it time to work.
Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Fact Box

Habit Forming

Yes

Therapeutic Class

NEURO CNS

References

  1. DailyMed. Chlordiazepoxide and amitriptyline hydrochloride. [Accessed 10 Apr. 2019] (online) Available from:
  2. MedlinePlus. Chlordiazepoxide. [Accessed 10 Apr. 2019] (online) Available from:
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User feedback

Once A Day
88%
Twice A Day
9%
Alternate Day
2%
Thrice A Day
2%
Depression
100%
Poor
100%
Difficulty in urination
50%
Constipation
50%
With food
100%
Expensive
100%
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Talent India
Address: 1601, Karnavati Estate, GIDC, Phase III, Vatva, Ahmedabad 382445, Gujarat, India.

Vendor Details

Country of origin: India

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