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    Amitriptyline + Chlordiazepoxide

    Information about Amitriptyline + Chlordiazepoxide

    Amitriptyline + chlordiazepoxide uses

    Amitriptyline+Chlordiazepoxide is used in the treatment of depression.

    How amitriptyline + chlordiazepoxide works

    This is a combination of two medicines: Amitriptyline and Chlordiazepoxide, which treats depression. Amitriptyline is a tricyclic antidepressant which increases the levels of chemical messengers in the brain that help in regulating the mood and treat depression. Chlordiazepoxide is a benzodiazepine (BZD) which works by increasing the action of GABA, a chemical messenger which suppresses the abnormal and excessive activity of the nerve cells in the brain.

    Common side effects of amitriptyline + chlordiazepoxide

    Constipation, Difficulty in urination, Weight gain, Confusion, Orthostatic hypotension (sudden lowering of blood pressure on standing), Tiredness, Blurred vision, Dryness in mouth, Increased heart rate, Uncoordinated body movement, Depression, Memory impairement
    Content Details
    Written By
    Dr. Saleh Rifai
    BCMAS, Pharm.D
    Reviewed By
    Dr. Ashish Ranjan
    MD (Pharmacology), MBBS
    Last updated on:
    19 Dec 2018 | 04:46 PM (IST)
    Want to know more?
    Read Our Editorial Policy

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    Frequently asked questions for Amitriptyline + Chlordiazepoxide

    Amitriptyline + Chlordiazepoxide

    Q. Are there any important warnings associated with use of Amitriptyline+Chlordiazepoxide?

    During the first few months of treatment, Amitriptyline+Chlordiazepoxide may increase suicidal thoughts or actions in some patients. Patients having mood or behavioral disorder have a high risk of developing suicidal thoughts and actions. You should pay close attention and report your doctor of any such behavior or mood changes. Make sure that you visit the doctor for the scheduled follow-up appointments.

    Q. Can I stop taking Amitriptyline+Chlordiazepoxide when my symptoms are relieved?

    No, you should continue to take Amitriptyline+Chlordiazepoxide, even if you feel well. If you stop Amitriptyline+Chlordiazepoxide suddenly, serious withdrawal symptoms may occur. Consult your doctor if the symptoms are relieved, he might decrease your dose gradually.

    Q. How to manage weight gain associated with the use of Amitriptyline+Chlordiazepoxide?

    There are reports which suggest that the use of Amitriptyline+Chlordiazepoxide can cause weight gain. If you maintain good eating habits and exercise regularly, you might not gain any weight. An important to remember is that it is easier to prevent weight gain than losing increased weight.

    Q. Can the use of Amitriptyline+Chlordiazepoxide cause sleepiness?

    Yes, Amitriptyline+Chlordiazepoxide can make you feel sleepy. Avoid driving, operating machinery, working at heights or participating in potentially dangerous activities till you know how this medicine affects you.

    Q. Can the use of Amitriptyline+Chlordiazepoxide affect my sexual life?

    The use of Amitriptyline+Chlordiazepoxide can affect the sexual life of both men and women. Most commonly caused problems are decreased sexual desire, erectile dysfunction (inability to develop or maintain erection during the sexual activity) and inability to reach orgasm. It can also cause a decrease in satisfaction and cause discomfort while having sex. If you experience these problems, discuss with your doctor.

    Q. Can I drink alcohol while taking Amitriptyline+Chlordiazepoxide?

    No, do not drink alcohol while you are taking Amitriptyline+Chlordiazepoxide. Drinking alcohol can increase the severity of drowsiness or sleepiness caused by Amitriptyline+Chlordiazepoxide.

    Q. Can the use of Amitriptyline+Chlordiazepoxide change the color of urine?

    Yes, Amitriptyline+Chlordiazepoxide can the change the color of the urine to blue or green. This change of color is expected while using Amitriptyline+Chlordiazepoxide, and it is not harmful. Your urine color becomes normal once you stop taking Amitriptyline+Chlordiazepoxide.

    Q. How long does Amitriptyline+Chlordiazepoxide take to work?

    Everybody responds differently to the treatment. In general, it can take several weeks to feel the full benefits of Amitriptyline+Chlordiazepoxide, although some people will start to feel better sooner. When taking Amitriptyline+Chlordiazepoxide, it is important to give it time to work.

    Q. What are the instructions for storage and disposal of Amitriptyline+Chlordiazepoxide?

    Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

    Content on this page was last updated on 19 December, 2018, by Dr. Varun Gupta (MD Pharmacology)