Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Tripath 5 mg/500 mg/15 mg Tablet SR is to be taken with food. Tripath 5 mg/500 mg/15 mg Tablet SR may cause stomach upset if taken empty stomach.
Tripath 5 mg/500 mg/15 mg Tablet SR is a combination of three antidiabetic medicines: Glibenclamide, Metformin and Pioglitazone. They work by different mechanisms to provide better control of blood sugar when single or dual therapy is not effective. Glibenclamide is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide. It works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin. Pioglitazone is a thiazolidinedione which further increases insulin sensitivity.
Taking pioglitazone with alcohol may affect blood glucose levels in patients with diabetes.
WEIGH RISKS VS BENEFITS
Tripath 5 mg/500 mg/15 mg Tablet SR may be unsafe to use during pregnancy. Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Tripath 5 mg/500 mg/15 mg Tablet SR is probably safe to use during lactation.
Limited human data suggests that the drug does not represent a significant risk to the baby. Monitor the breastfed baby’s blood sugar during treatment with Tripath 5 mg/500 mg/15 mg Tablet SR
Your ability to drive may be affected if your blood sugar is low or high. If this happens, do not drive.
Tripath 5 mg/500 mg/15 mg Tablet SR is probably unsafe to use in patients with kidney disease and should be avoided. Please consult your doctor.
Tripath 5 mg/500 mg/15 mg Tablet SR should be used with caution in patients with liver disease. Dose adjustment of Tripath 5 mg/500 mg/15 mg Tablet SR may be needed. Please consult your doctor. Use of Tripath 5 mg/500 mg/15 mg Tablet SR is not recommended in patients with severe liver disease.