Glibenclamide + Metformin + Pioglitazone

Glibenclamide + Metformin + Pioglitazone is a combination of three antidiabetic medicines: Glibenclamide , Metformin and Pioglitazone. They work by different mechanisms to provide better control of blood sugar when single or dual therapy is not effective. Glibenclamide is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide. It works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin. Pioglitazone is a thiazolidinedione which further increases insulin sensitivity.

Hypoglycemia (low blood glucose level), Nausea, Diarrhea, Headache, Weight gain, Anemia (low number of red blood cells), Vomiting, Flatulence