Tresnil Tablet

Alprazolam (0.5mg)+ Melatonin (NA)

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Tresnil Tablet is used to treat insomnia. It helps to calm the brain by decreasing the abnormal and excessive activity of the nerve cells. It also regulates the sleep cycle and helps the patient to fall asleep quickly.

Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 30 Oct 2026 | 01:03 AM (IST)

₹17.2 MRP ₹18.145% off

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Gurgaon

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General Information

Contains

Alprazolam (0.5mg)+ Melatonin (NA)

Marketer

Intel Pharmaceuticals

Storage

Store below 30°C

The content is shown in English

Product introduction

Tresnil Tablet should be taken with or without food. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration advised by your doctor as it has high habit-forming potential. However, take it as advised by your doctor because it is not recommended for long-term use. Inform your doctor if you are suffering from any liver or kidney problems before taking this medicine. You should avoid smoking and alcohol while using this medicine. Regular monitoring of blood sugar levels is required while taking this medicine.

Some common side effects of this medicine include confusion, tiredness, and memory impairment. It may also cause dizziness and sleepiness. So, do not drive or do anything that requires mental focus until you know how this medicine affects you. It may cause weight gain or weight loss depending upon person to person. To prevent weight gain, you can eat a healthy balanced diet, avoid snacking with high-calorie food, and exercise regularly. However, weight loss can be managed by consulting a dietitian who can help you in increasing your food portions.

Take caution while taking medicine if you are suffering from liver disease. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding.

Uses of Tresnil Tablet

Treatment of Insomnia

Benefits of Tresnil Tablet

Treatment of Insomnia
Tresnil Tablet is a combination of two medicines that helps treat insomnia (difficulty falling or staying asleep) in people who have problems related to their sleeping habits. Insomnia may cause you to wake up earlier than usual and you may find it difficult to go back to sleep. It works by slowing down the abnormal activity of nerves in the brain to allow sleep. It also improves the sleep-wake cycle and restores it to normal. This helps you relax, feel calm, and more energetic. It also helps you concentrate better and improves your quality of life.

Side effects of Tresnil Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Tresnil

Confusion
Drowsiness
Tiredness
Uncoordinated body movements
Depression
Memory impairment

How to use Tresnil Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Tresnil Tablet may be taken with or without food.

How Tresnil Tablet works

Tresnil Tablet contains alprazolam and melatonin. Alprazolam enhances the action of GABA, a chemical messenger that reduces activity in the brain and produces a calming effect. Melatonin is a hormone that helps regulate the body's internal clock and sleep-wake cycle.

Quick tips

Tresnil Tablet is prescribed for the treatment of insomnia.
It can take a week or two after starting this treatment before the effect begins to build up, and 4-6 weeks before you feel the full benefit. Do not stop taking it after a week or two, feeling it is not helping.
Do not stop taking Tresnil Tablet unless your doctor tells you to do so. Stopping treatment suddenly can cause problems and your doctor will probably want you to reduce your dose gradually when this becomes necessary.
Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress.
Inform your doctor if you have liver disease.
Inform your doctor if you are pregnant or breastfeeding.
Tresnil Tablet is prescribed for the treatment of insomnia.
It can take a week or two after starting this treatment before the effect begins to build up, and 4-6 weeks before you feel the full benefit. Do not stop taking it after a week or two, feeling it is not helping.
Do not stop taking Tresnil Tablet unless your doctor tells you to do so. Stopping treatment suddenly can cause problems and your doctor will probably want you to reduce your dose gradually when this becomes necessary.
Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress.
Inform your doctor if you have liver disease.
Inform your doctor if you are pregnant or breastfeeding.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Tresnil Tablet

Pregnancy

CONSULT YOUR DOCTOR

Tresnil Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CONSULT YOUR DOCTOR

Tresnil Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

UNSAFE

Tresnil Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Tresnil Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

UNSAFE

Tresnil Tablet is unsafe to use in patients with liver disease and should be avoided.
There is very limited experience on use of Tresnil Tablet in patients with underlying liver disease.

Frequently asked questions

What is Tresnil Tablet used for?

Tresnil Tablet can be used to manage insomnia, jet lag and short term anxiety as it may help provide a calming and sedative effect.

What is the correct way to take Tresnil Tablet?

Tresnil Tablet can be taken with or without food usually at a fixed time each day. The exact duration and dose will be decided by your doctor. Do not increase the dose or take additional doses if you are unable to sleep.

Can Tresnil Tablet help me fall asleep faster?

Tresnil Tablet has a sedative effect that regulates sleep cycle and helps brain to calm down that induces faster sleep. However, the degree of benefit depends on the underlying sleep problem and the individual condition.

Can Tresnil Tablet be used for jet lag?

Tresnil Tablet may help with sleep timing problems associated with jet lag in some circumstances if advised by the doctor.

Can I take Tresnil Tablet to treat my anxiety?

Tresnil Tablet may be prescribed by the doctor to manage short term anxiety but it is not treat anxiety related disorders. Consult a doctor and get yourself evaluated if you think you have anxiety issues.

Am I becoming dependent on Tresnil Tablet?

Yes, Tresnil Tablet may cause dependence and carries risks of misuse and addiction, even when taken as prescribed. The risk may increase with prolonged use or higher doses. Use it only under medical supervision and exactly as advised.

Can I take Tresnil Tablet with other sleeping pills or medicines that cause drowsiness?

Do not combine it with other sedatives or sleeping medicines unless specifically advised by the doctor for your health condition. Combining it with medicines that cause central nervous system depression can increase sedation and may cause serious breathing problems.

Can Tresnil Tablet affect memory or concentration?

Yes. Tresnil Tablet can impair memory, attention and coordination. Avoid activities that require your full alertness like driving, operating heavy machinery etc. if you feel sleepy.

What should I do if I take more than the prescribed dose of Tresnil Tablet?

Seek urgent medical advice if you take more than prescribed, especially if you experience extreme sleepiness, confusion, poor coordination or slow or difficult breathing. Do not combine an extra dose with alcohol or other sedatives.

Is Tresnil Tablet suitable for long-term treatment of insomnia?

Long term use of Tresnil Tablet can cause dependence and withdrawal, and ongoing sleep difficulties require treatment of the underlying cause that may need a different management approach rather than relying alone on the medication. Include mindfulness activities, brain calming methods, and follow a discipline routine to help improve your overall lifestyle and sleep cycle.

Fact Box

Habit Forming

Yes

Therapeutic Class

NEURO CNS

References

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Intel Pharmaceuticals
Address: A/179,PEOPLES COOPERATIVE COLONY PS-KANKARBAGH PATNA BR 800020 IN

Vendor Details

Country of origin: India

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Tresnil Tablet

Tresnil Tablet

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Tresnil Tablet

Benefits of Tresnil Tablet

Side effects of Tresnil Tablet

How to use Tresnil Tablet

How Tresnil Tablet works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

What is Tresnil Tablet used for?

What is the correct way to take Tresnil Tablet?

Can Tresnil Tablet help me fall asleep faster?

Can Tresnil Tablet be used for jet lag?

Can I take Tresnil Tablet to treat my anxiety?

Am I becoming dependent on Tresnil Tablet?

Can I take Tresnil Tablet with other sleeping pills or medicines that cause drowsiness?

Can Tresnil Tablet affect memory or concentration?

What should I do if I take more than the prescribed dose of Tresnil Tablet?

Is Tresnil Tablet suitable for long-term treatment of insomnia?

Fact Box

Habit Forming

Therapeutic Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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