Tresnil Tablet is a combination of two medicines: Alprazolam and melatonin which help you sleep. Alprazolam is a benzodiazepine. It works by increasing the action of GABA, a chemical messenger which suppresses the abnormal and excessive activity of the nerve cells in the brain and induces sleep. Melatonin is a natural hormone which helps to regulate the sleep-wake cycle.
Taking melatonin with alcohol may cause sleepiness and the effects may become even stronger.
WEIGH RISKS VS BENEFITS
Tresnil Tablet is unsafe to use during pregnancy. There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.
Tresnil Tablet is probably unsafe to use during lactation.
Limited human data suggest that the drug could represent a significant risk to the baby.
Tresnil Tablet may make you feel dizzy, sleepy, tired, or decrease alertness. If this happens, do not drive.
Tresnil Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Tresnil Tablet may not be needed in these patients. Please consult your doctor.
Tresnil Tablet should be used with caution in patients with liver disease. Dose adjustment of Tresnil Tablet may be needed. Please consult your doctor. There is very limited experience on use of Tresnil Tablet in patients with underlying liver disease.