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Thiopta Injection

Thiotepa (15mg)
Genuine
Authenticity Assured
Prescription
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Thiopta Injection is used in the treatment of cancers of the brain, breast, lungs, and ovaries. It is used in combination with other cancer medicine during hematopoietic progenitor cell transplantation (HPCT). It may be also used to treat other conditions, as determined by the doctor.

Written By Dr. Syeda Aafia, MBA, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 23 Mar 2026 | 11:29 AM (IST)
₹15009 MRP ₹1687511% off 
 
 
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Thiopta Injection
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General Information

The content is shown in English
Thiopta Injection image
Thiopta Injection image

Product introduction

Thiopta Injection is generally given under the supervision of a healthcare professional. Your doctor will decide the dose and duration of the treatment based on the severity of your condition and what you are being treated for. It may take several weeks or months for you to see or feel the benefits but do not stop getting the injection unless your doctor tells you to.

The most common side effects of this medicine include decreased white blood count, anemia, low blood platelets, increased liver enzymes, increased bilirubin in the blood, mucosal inflammation, hemorrhage, diarrhea, blood in urine, and rash. This medicine may reduce the number of blood cells in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with kidneys, liver, and heart function during treatment with this medicine.

Before taking it, tell your doctor if you have bleeding, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Benefits of Thiopta Injection

Ovarian cancer
Ovarian cancer is a cancer that begins in the female organs that produce eggs (ovaries). This type of cancer is usually detected very late and can be fatal too. It usually spreads to the pelvis and stomach. Thiopta Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is an effective medicine but has some side effects that may be bothersome. So, you should discuss the risks and benefits with your doctor.
Non-small cell lung cancer
Non-small cell lung cancer is one of the major kinds of lung cancer and it affects both smokers as well as non-smokers. Thiopta Injection helps treat non-small cell lung cancer and may be given alone or in combination with other medicines. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

Side effects of Thiopta Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Thiopta
  • Anemia (low number of red blood cells)
  • Low blood platelets
  • Decreased white blood cell count (neutrophils)
  • Increased liver enzymes
  • Increased bilirubin in the blood
  • Mucosal inflammation
  • Hemorrhage
  • Rash
  • Diarrhea
  • Blood in urine

How to use Thiopta Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Thiopta Injection works

Thiopta Injection is an anti-cancer medication. It works by damaging the genetic material (DNA and RNA) of the cancer cells. This stops their growth and multiplication.

All substitutes for Thiopta Injection

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

  • Thiopta Injection is given as an intravenous infusion (IV infusion) under the supervisión of a doctor.
  • Do not skip any dose and complete the course as suggested by your doctor.
  • Use an effective method of birth control to avoid pregnancy while taking this medication.
  • Your doctor may get regular blood tests done to monitor your blood cell count, platelet count and liver function.
  • It makes you feel dizzy. Do not drive or operate machinery until you know how it affects you.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Thiopta Injection. Please consult your doctor.
Pregnancy

Pregnancy

UNSAFE
Thiopta Injection is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.
Breast feeding

Breast feeding

UNSAFE
Thiopta Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving

Driving

UNSAFE
Thiopta Injection may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
It is likely that certain adverse events of Thiopta Injection are dizziness, headache, and blurred vision which could affect your ability to drive.
Kidney

Kidney

CAUTION
Thiopta Injection should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Liver

Liver

CAUTION
Thiopta Injection should be used with caution in patients with severe liver disease. Dose adjustment may be needed.
Regular monitoring of liver function tests may be advised while you are taking this medicine.

Interaction with drugs

Taking Thiopta with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Life-threatening

Pegfilgrastim (Injection Route)

Do not consume Thiotepa from 14 days before until 24 days after taking Pegfilgrastim. Please consult your doctor.
Life-threatening

Sargramostim (Injection Route)

Do not consume Thiotepa from 1 day before until 1 day after taking Sargramostim. Please consult your doctor.
Life-threatening

Lenograstim (Injection Route)

Do not consume Lenograstim from 24 hours before until 24 hours after undergoing cytotoxic chemotherapy.
Life-threatening

Molgramostim (Injection Route)

Do not consume Thiotepa from 1 day before until 1 day after taking Molgramostim. Please consult your doctor.
Life-threatening

Natalizumab (Injection Route)

Do not consume Natalizumab with Thiotepa.

Fact Box

Chemical Class

Organic thiophosphoric acid derivative

Habit Forming

No

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Alkylating Agents

References

  1. Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1685.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1355-56.
  3. Thiotepa. Lugano, Switzerland: ADIENNE SA; 1959 [revised Jan. 2017]. [Accessed 27 Mar. 2019] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Celon Laboratories Ltd
Address: Plot No 264, Patrika Nagar Madhapur, Hitech City Hyderabad, Telangana India - 500081

Vendor Details

Country of origin: India
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