Themibutol 600 mg Tablet

Prescription Required

Overview

Uses of Themibutol Tablet

Themibutol 600 mg Tablet is used in the treatment of tuberculosis.

Themibutol Tablet side effects

Common
  • Visual impairment
  • Color blindness

How to use Themibutol Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Themibutol 600 mg Tablet is to be taken with food.

How Themibutol Tablet works

Themibutol 600 mg Tablet is an antibiotic. It works by slowing the growth of bacteria that causes tuberculosis.

Themibutol Tablet related warnings

Alcohol
Interaction with alcohol is unknown. Please consult your doctor.
Pregnancy
WEIGH RISKS VS BENEFITS
Themibutol 600 mg Tablet may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Lactation
SAFE
Themibutol 600 mg Tablet is safe to use during lactation. Human studies have shown that either the drug does not pass into the breastmilk in significant amount or is not expected to cause toxicity to the baby.
Driving
Do not drive unless you are feeling well.
Themibutol 600 mg Tablet occasionally causes sight problems and tingling or numbness in hand or feet. After taking this medicine you should not drive until you know how it affects you.
Kidney
CAUTION
Themibutol 600 mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Themibutol 600 mg Tablet may be needed. Please consult your doctor.
Kidney function tests are advisable before the start of this medicine.
Liver
CAUTION
Themibutol 600 mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Themibutol 600 mg Tablet may be needed. Please consult your doctor.

What if you miss a dose of Themibutol Tablet?

If you miss a dose of Themibutol 600 mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Themibutol 600 mg Tablet
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Expert Advice

  • Themibutol 600 mg Tablet is effective at treating tuberculosis when taken together with other antibacterial drugs.
  • It has to be taken for several months in order for it work properly (usually 6 months).
  • Take it with food to avoid stomach upset.
  • It can lower your blood sugar. If you have diabetes, monitor your blood sugar regularly.
  • Your doctor may monitor your liver function, vision and thyroid function while on treatment with this medicine.
  • Avoid consuming alcohol while taking this medication.
  • Do not stop taking Themibutol 600 mg Tablet even if you start to feel better. Stopping early can  can result in treatment failure and in the development of drug-resistant tuberculosis. This can be life-threatening and lead to other serious health risks.

Interaction with Drugs

Taking Themibutol with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Sodamax, Sobinix, Sobimed
MINOR
Brand(s): Magflux, Magasip
MINOR

FAQs

Q. Does Themibutol cause blindness?

Optic neuritis (inflammation of nerve fibers that transmit visual information from your eye to the brain) is one of the side effects of Themibutol which causes several forms of eye defect. Although these conditions are reversible upon discontinuation of the drug, rare cases of irreversible blindness have also been reported. Please contact your doctor immediately if you notice any of these symptoms: decreased clearness of vision, loss of vision, disturbed vision due to blind spots, color blindness, visual field defect and eye pain

Q. Does Themibutol induce hyperuricemia/how does Themibutol induce hyperuricemia?

Yes. Increase in blood levels of uric acid is a side effect of Themibutol. It increases the retention of uric acid in the body by decreasing the excretion of urates (uric acid) by the kidneys

Q. How does Themibutol work in the body?

Themibutol is an antibiotic effective against tuberculosis causing bacteria. It suppresses the growth of the bacteria by interfering with the formation of the outer protective covering (cell wall) of the bacteria, thereby weakening the bacteria

Q. What is Themibutol toxicity/How does Themibutol cause optic neuritis/how does Themibutol affect vision?

Themibutol toxicity involves toxic effects on the eyes (optic neuritis/optic neuropathy) which are related to the dose and duration of Themibutol treatment. It causes optic neuritis (inflammation of nerve fibers in the eye) by interfering with important cellular activities (mitochondrial toxicity) in the nerve cells and inducing nerve damage (neuropathy) thereby affecting the transmission of visual information from the eye to brain. The symptoms of Themibutol induced optic neuritis include: decreased clearness of vision, loss of vision, disturbed vision due to blind spots, color blindness, visual field defect and eye pain

Q. What does Themibutol treat?

Themibutol is an antibiotic effective against tuberculosis causing bacteria. It is used in the prevention, treatment and second time treatment of tuberculosis (a serious infection caused by bacteria that affects the lungs and in certain cases other parts of the body)

Q. Is Themibutol bacteriostatic or bactericidal?

Themibutol is both a bacteriostatic and a bactericidal antibiotic. It suppresses the growth of bacteria (bacteriostatic) by interfering with the formation of the outer protective covering (cell wall) of the bacteria, thereby weakening it and causing cell death in certain cases (bactericidal)

Q. Is Themibutol hepatotoxic?

Liver toxicities are among the known side effects of Themibutol. Inflammation of liver (hepatitis), abnormal liver function causing yellowing of skin and eyes (jaundice), abnormal liver function tests (blood tests to assess health of liver) and very rarely liver failure have been noted in patients receiving multi drug (including Themibutol) treatment for tuberculosis. Please contact your doctor before taking Themibutol if you have any liver problems

Q. Is Themibutol toxicity reversible?

In most cases Themibutol toxicities are related to dose (depends upon the quantity of Themibutol you take) and duration of treatment and are reversible upon discontinuation. However, serious irreversible damage to eye and liver has been reported in rare cases

Q. Is Themibutol chemotherapy?

Themibutol is an antibiotic used in the treatment of tuberculosis. Do not confuse it with chemotherapy or chemo drugs used for the treatment of cancer

Q. Themibutol is effective against?

Themibutol is effective against most tuberculosis causing bacteria belonging to Mycobacterium family (M. tuberculosis, M. avium complex, M. kansasii, M. marinum).
Information last updated by Dr. Varun Gupta, MD Pharmacology on 12th Apr 2018.
The medicine details are for information purpose only. Consult a doctor before taking any medicine.
Manufacturer/Marketer Address
11/12, Udyog Nagar, S. V. Road, Goregaon (W), Mumbai- 400104.
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