Tenelnat-M Tablet ER

Prescription Required

Introduction of Metformin

Tenelnat-M Tablet ER is a combination of two medicines that control high blood sugar levels in people with type 2 diabetes mellitus. This helps prevent serious complications of diabetes such as kidney damage and blindness and may also reduce your chances of having a heart attack or stroke.

Tenelnat-M Tablet ER is best taken with food to avoid nausea and abdominal pain. You should take it regularly, at the same time each day, to get the most benefit. You should not stop taking this medicine unless your doctor recommends it. Your lifestyle plays a big part in controlling diabetes. Therefore, it is important to stay on the diet and exercise program recommended by your doctor while taking this medicine. 
The most common side effects of this medicine include nausea, vomiting, taste change, diarrhea, abdominal pain, and loss of appetite. Some people may develop hypoglycemia (low blood sugar level) when this medicine is taken along with other antidiabetic medicines, alcohol, or upon skipping a meal. Monitor your blood sugar levels regularly while taking it.
Before taking this medicine, inform your doctor if you have any kidney, liver, or heart problems. Pregnant or breastfeeding women should also consult their doctor before taking it. Your doctor will check your kidney function tests before starting treatment with it. Avoid excessive alcohol intake while taking it as this may increase the risk of developing some side effects.

Introduction of Teneligliptin

Tenelnat-M Tablet ER is a combination of two medicines that control high blood sugar levels in people with type 2 diabetes mellitus. This helps prevent serious complications of diabetes such as kidney damage and blindness and may also reduce your chances of having a heart attack or stroke.

Tenelnat-M Tablet ER is normally prescribed when diet and exercise alone or other medicines have not been enough to control your blood sugar level. Your doctor may prescribe it alone or along with other diabetes medicines. It can be taken with or without food. The dose will depend on your condition, and blood sugar levels, but you should use it as advised by your doctor.

You should take it regularly, at the same time each day, to get the most benefit and you should not stop unless your doctor recommends it. It is controlling your blood sugar levels and helping to prevent serious complications in the future. It is important to stay on the diet and exercise program recommended by your doctor while taking this medicine. Your lifestyle plays a big part in controlling diabetes.

The most common side effect of taking this medicine is a headache. This is usually minor and improves with time. Low blood sugar level (hypoglycemia) is a possible side effect if you are also taking other diabetes medicines like insulin or sulphonylurea, so you need to know how to recognize and deal with it. You can carry sugar or glucose candy to control low blood sugar level. Contact your doctor if the side effects worry you or if they do not go away.

Before taking this medicine, let your doctor know if you have ever had kidney disease, heart or pancreas problems, or if you drink a lot of alcohol. Pregnant or breastfeeding women should also consult their doctor before taking it. Some other medicines you are taking may interfere with it so make sure your doctor knows about all the other medicines you are using. Limit your alcohol intake while taking this medicine because it can increase your risk of developing low blood sugar levels. You may need regular tests such as kidney function and blood glucose levels to check that the medicine is working properly.

Uses of Metformin

Uses of Teneligliptin


Side effects of Metformin

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Tenelnat-M

  • Nausea
  • Vomiting
  • Taste change
  • Diarrhea
  • Abdominal pain
  • Loss of appetite

Side effects of Teneligliptin

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Tenelnat-M

  • Headache
  • Hypoglycaemia (low blood sugar level) in combination with insulin or sulphonylurea
  • Upper respiratory tract infection
  • Nasopharyngitis (inflammation of the throat and nasal passages)

How Metformin works

Tenelnat-M Tablet ER is an anti-diabetic medication (biguanide). It works by lowering glucose production in the liver, delaying the absorption of sugar (glucose) from the intestines, and increasing the body's sensitivity to insulin.

How Teneligliptin works

Tenelnat-M Tablet ER is an antidiabetic medication. It works by increasing the release of insulin from the pancreas and decreasing the hormones that raise blood sugar levels. This reduces the fasting and postmeal sugar levels.

Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Tenelnat-M Tablet ER.
Pregnancy
CONSULT YOUR DOCTOR
Information regarding the use of Tenelnat-M Tablet ER during pregnancy is not available. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Tenelnat-M Tablet ER during breastfeeding is not available. Please consult your doctor.
Driving
CAUTION
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Kidney
CAUTION
Tenelnat-M Tablet ER should be used with caution in patients with kidney disease. Dose adjustment of Tenelnat-M Tablet ER may be needed. Please consult your doctor.
Use of Tenelnat-M Tablet ER is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.
Liver
CAUTION
Tenelnat-M Tablet ER should be used with caution in patients with liver disease. Dose adjustment of Tenelnat-M Tablet ER may be needed. Please consult your doctor.
Tenelnat-M Tablet ER is generally started with low dose in patients with mild to moderate liver disease and its use is not recommended in patients with severe liver disease.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
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Quick tips

Metformin

  • You have been prescribed Metformin to control the blood sugar level and reduce the risk of diabetic complications such as heart attacks.
  • Chances of weight gain and low blood sugar are lesser with this medicine as compared to other diabetes medicines.
  • Hypoglycemia (low blood sugar level) may occur when taken along with other antidiabetic medicines, alcohol or on delaying/skipping a meal. Carry a sugar source with you for immediate relief.
  • Tell your doctor immediately if you experience any deep or rapid breathing, persistent nausea, vomiting, and stomach pain as Metformin may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.
  • Prolonged use of Metformin may lead to vitamin B12 deficiency which may lead to anemia, causing fatigue, pale skin, shortness of breath or headache. Notify your doctor if you experience any of these as you may require supplements.
  • Your doctor will monitor your blood sugar levels and kidney functions regularly while you are taking this medication.

Teneligliptin

  • Teneligliptin should be taken at the same time every day since this helps you remember to take it.
  • Be careful while driving or operating machinery until you know how Teneligliptin affects you.
  • It may cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
  • Always carry some sugary food or fruit juice with you in case you experience hypoglycemia symptoms such as cold sweats, cool pale skin, tremor and anxiety.
  • Inform your doctor if you notice joint pains or develop symptoms such as stomach pain, nausea and/or vomiting.

Fact Box

Habit Forming
No
Therapeutic Class
ANTI DIABETIC

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FAQs

Metformin

Q. What does Metformin do exactly?

People with type 2 diabetes are not able to make enough insulin or respond normally to the insulin made by their bodies. When this happens, the concentration of sugar/glucose increases in the blood. Metformin acts in several ways to reduce the increased levels of sugar in blood. Metformin decreases glucose production from the liver and decreases absorption of glucose from the intestine after taking food while improving the sensitivity of the body organs and muscles towards insulin. This helps improve the uptake of glucose from the blood. It also helps your body to respond better to the insulin it makes naturally.

Q. Does Metformin cause weight loss?

Yes, Metformin has been shown to cause weight loss in people who are overweight or obese. It may also cause a modest loss in weight in those overweight and obese individuals who are at risk for diabetes. In addition, patients who are sensitive or resistant to insulin may also show weight loss. But, do not start taking this medicine for weight loss on your own. Consult your doctor for the same.

Q. What are the benefits of taking Metformin?

Metformin is one of the first medicines that is given to patients with high blood sugar levels. It helps control blood sugar levels. It promotes the body’s response to the insulin made by the pancreas, decreases the amount of sugar made by the liver and decreases the amount of sugar absorbed by the intestines. Unlike other oral antidiabetic medicines, Metformin when taken alone, rarely causes low blood sugar as it prevents the pancreas from secreting more insulin. In addition to being a great medicine to lower blood sugar levels, it also helps in controlling weight gain.

Q. Can Metformin make you sleepy?

Metformin usually does not cause sleepiness and is well tolerated. However, the use of Metformin may rarely cause sleep disorders and insomnia. Sleepiness may be due to a very serious side effect called lactic acidosis, which particularly occurs if your kidneys are not working properly. Contact your doctor if you feel sleepy or tired while taking Metformin.

Q. How to take Metformin?

Take Metformin with or after a meal. Do not crush or chew the tablets and swallow it with a glass of water. If your doctor has prescribed one tablet a day, prefer taking it in the morning with breakfast. If you have been prescribed two tablets a day, then take one in the morning and other in the evening with dinner. In case of three doses a day, apart from morning and evening, you can take it with lunch. Taking Metformin with meals will reduce its digestive problems like indigestion, nausea, vomiting, diarrhea, stomach ache and loss of appetite.
Teneligliptin

Q. Does Teneligliptin cause weight gain?

No, Teneligliptin is not known to cause weight gain by itself. However, keeping a healthy weight is an important part of managing diabetes. Consult your doctor if you experience weight gain while taking Teneligliptin.

Q. Is Teneligliptin bad for your kidneys?

No, Teneligliptin is not bad for your kidneys if your kidney function is normal. However, it is important to inform your doctor if you have, or ever had, any kidney problems. If you have kidney problems, you may need dose modification.

Q. Do I still have to manage my diet and exercise while on Teneligliptin?

Yes, it is important to manage your diet and exercise while taking Teneligliptin. In addition to medicine, making healthy food choices and being physically active are also important to effectively manage blood sugar levels. You may consult a dietitian and follow a diet chart that suits you best. A well-balanced diet is one part of a healthy lifestyle for people with type 2 diabetes. Additionally, thirty minutes of exercise such as a brisk walk is recommended.

Q. Can my blood sugar levels go too low on Teneligliptin?

Yes, it is possible that your blood sugar levels may become very low (hypoglycemia). The chances are higher if you are on any other antidiabetic medicine or insulin along with Teneligliptin. Additionally, blood sugar levels can take a huge dip if you skip meals, exercise more than usual, or if you have taken an overdose of Teneligliptin. If you experience a sudden fall in your sugar levels, inform your doctor. The doctor may suggest dose modification to prevent your blood sugar levels from decreasing significantly (hypoglycemia). Follow your doctor’s advice and monitor your blood sugar levels regularly.

Q. What is the most important information I should know about Teneligliptin?

Teneligliptin is safe to use if taken in the dose and duration prescribed by the doctor. However, in rare cases, some serious side effects can also be observed. In some people, Teneligliptin may cause inflammation of the pancreas (pancreatitis) which could be severe and can even lead to death. If you experience severe and persistent pain in your stomach area (abdomen), stop the medication and immediately contact your doctor. Teneligliptin can also cause heart failure. This means the heart is not able to pump blood well enough, therefore, inform your doctor if you have or ever had heart problems before you start taking Teneligliptin. In addition to that, problems related to kidneys should also be discussed with the doctor.

Q. How long do I need to take Teneligliptin?

Teneligliptin only helps to manage your blood sugar levels but does not cure your diabetes. Keep taking Teneligliptin as long as your doctor recommends it. You may have to take it lifelong. It is important to keep your blood sugar levels under control as any fluctuations in your blood sugar levels may cause serious problems. Therefore, do not stop taking it without talking to your doctor.

Q. What if I miss a dose of Teneligliptin?

If you miss a dose, take it as soon as you remember. If in case you do not remember until it is time for your next dose, skip the missed dose and go back to your regular schedule. Do not take two doses of Teneligliptin at the same time.

Q. Is Teneligliptin safe to be taken for a long term?

Yes, it is safe to take Teneligliptin for a long time. Its long-term use, which can continue for months, years or even lifelong, has not shown any harmful effects. Keep taking Teneligliptin as long as your doctor recommends it. Remember, Teneligliptin only helps to keep your blood sugar levels under control but does not cure your diabetes.

Q. What will happen if I accidentally take more than the prescribed dose of Teneligliptin?

If you have accidentally taken more than the prescribed dose of Teneligliptin, your blood sugar levels may become too low (hypoglycemia). This hypoglycemia may be mild or severe. Monitor your blood sugar levels more frequently for the next 24 hours. Mild episodes of hypoglycemia (with symptoms like anxiety, sweating, weakness, tremors, fast heartbeat) can usually be corrected with the help of sugary foods such as sugar or glucose candy, fruit juice and glucose/glucon-D. However, it is important to consult your doctor to decide the further course of treatment. More severe episodes of hypoglycemia may even lead to a seizure (fit) or unconsciousness. This can be life-threatening and immediate medical help may be required.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Metformin hydrochloride. Princeton, New Jersey: Bristol-Myers Squibb Company. [Accessed 08 Apr. 2019] (online) Available from:External Link
  2. Kishimoto M. Teneligliptin: A DPP-4 inhibitor for the treatment of type 2 diabetes. Diabetes Metab Syndr Obes. 2013;6:187-95. [Accessed 08 Apr. 2019] (online) Available from:External Link
  3. Metformin hydrochloride oral solution. Gloversville, New York: Ranbaxy Pharmaceuticals Inc.; 2003. [Accessed 08 Apr. 2019] (online) Available from:External Link

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Natco House, Road No.2, Banjara Hills, Hyderabad-500 034, India
Country of origin: India

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