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Last updated on:
23 May 2019 | 11:30 AM (IST)
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Temotide 250 mg Tablet


Overview

Uses of Temotide Tablet

Temotide Tablet side effects

Common
  • Memory loss
  • Rash
  • Headache
  • Dizziness
  • Convulsion
  • Coordination disorder
  • Insomnia (difficulty in sleeping)
  • Vomiting
  • Weakness
  • Nausea
  • Loss of appetite
  • Hair loss
  • Fatigue
  • Fever
  • Diarrhea
  • Constipation
  • Hemiparesis (weakness on one side of the body)
  • Viral infection

How to use Temotide Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Temotide 250 mg Tablet is to be taken empty stomach.

How Temotide Tablet works

Temotide 250 mg Tablet is an anti-cancer medication. It enters the brain tissues and works by damaging the genetic material (DNA and RNA) of the cancer cells. This stops their growth and multiplication.

Temotide Tablet related warnings

Alcohol
Interaction with alcohol is unknown. Please consult your doctor.
Pregnancy
WEIGH RISKS VS BENEFITS
Temotide 250 mg Tablet is unsafe to use during pregnancy.
There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.
Lactation
UNSAFE
Temotide 250 mg Tablet is unsafe to use during lactation. Data suggests that the drug may cause toxicity to the baby, or the mother is suffering from a condition in which breastfeeding is not advisable.
Driving
Temotide 250 mg Tablet may make you feel dizzy, sleepy, tired, or decrease alertness. If this happens, do not drive.
Kidney
Temotide 250 mg Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Temotide 250 mg Tablet may not be needed in these patients. Please consult your doctor.
Cautious use is advised in patients with severe kidney disease while they are taking Temotide 250 mg Tablet.
Liver
Temotide 250 mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Temotide 250 mg Tablet may be needed. Please consult your doctor.
Limited information is available on the use of Temotide 250 mg Tablet in these patients. No dose adjustment is recommended in patients with mild to moderate liver disease.

What if you miss a dose of Temotide Tablet?

If you miss a dose of Temotide 250 mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Temotide 250 mg Tablet
₹1200/Tablet
Glioz 250mg Tablet
Dr Reddy's Laboratories Ltd
₹4880.3/Tablet
307% costlier
Temotor 250mg Tablet
Torrent Pharmaceuticals Ltd
₹1443.19/Tablet
20% costlier
Gliogen 250mg Tablet
Samarth Life Sciences Pvt Ltd
₹1375/Tablet
15% costlier
Gliozolamide 250mg Tablet
Biochem Pharmaceutical Industries
₹3515.16/Tablet
193% costlier

Expert Advice

  • Swallow full tablets on an empty stomach, one hour before your meal.
  • Avoid being near people who are sick or have infections. Consult your doctor if you develop symptoms of opportunistic infections (such as Pneumocystis jirovecii pneumonia) and reactivation of infections (such as hepatitis B virus) Using temozolomide may increase your risk of developing certain types of bone marrow cancer. Be aware about your specific risk.
  • You may be given medication to prevent nausea or other side effects while you are receiving temozolomide.
  • Your blood will be tested frequently during treatment to monitor the side effects of temozolomide on your blood cells as you may have a small risk of other changes in blood cells, including leukemia.
  • Avoid activities that may increase your risk of bleeding or injury. Use extra care to prevent bleeding while shaving or brushing your teeth.
  • Do not drink alcohol while taking temozolomide.
  • Do not drive or operate machinery while using temozolomide as it may make you tired or sleepy.
  • Both male and female patients should take effective contraceptive precautions during and after 6 months of treatment. Male patients should seek advice on conservation of sperm prior to treatment as temozolomide treatment may cause infertility.

Patient Concerns

Questions Related to Temotide

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Brain tumor that why doctor suggest to do test
Dr. Jyoti Kapoor Madan
Psychiatrist
Please consult a neuro surgeon.
MRI report says left frontal convexity meningioma" what is the meaning and is it a brain tumor?"
Dr. Vikas Sharma
Neurologist
Yes its tumor Show 2 neurosurgery
arrow
Do you have any questions related to Temotide 250 mg Tablet?

FAQs

Q. What is Temotide used for/ what does Temotide treat/ Is Temotide chemotherapy/ is Temotide cytotoxic/ is Temotide a radiosensitizer?

Temotide is an anti-cancer (antineoplastic or cytotoxic) chemotherapy drug. It is used to treat specific types of brain tumor. It is a radiosensitizer

Q. Is Temotide effective/ does Temotide work?

Temotide is effective and works for patients if taken at recommended dosage and duration as recommended by the doctor

Q. How is Temotide given/administered/ metabolized/ how long does Temotide stay in the body?

Temotide is given as a capsule and is taken by mouth. It should be administered in the fasting state, at least one hour before meal. It is rapidly metabolized at physiologic pH to the active monomethyl triazenoimidazole carboxamide (MTIC). The half-life (t1/2) in plasma is approximately 1.8 hours

Q. How does Temotide cross the blood-brain barrier?

Temotide because of its small size and lipophilic properties is able to cross the blood-brain barrier rapidly and is present in the cerebrospinal fluid

Q. Does Temotide cause hair loss?

Hair loss is a side effect of using Temotide. Always follow doctor's advice regarding its use

Q. Is Temotide FDA approved?

Temotide is a FDA approved drug.

Related Products

Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1687.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1324-25.
  3. Temozolomide. Whitehouse Station, New Jersey: Merck & Co., Inc.; 1999 [revised Sep. 2015]. [Accecssed 25 Jan. 2019] (online) Available from:External Link
  4. U.S. National Library of Medicine. Temozolomide. [Accessed 27 Mar. 2019] (online) Available from:External Link
Manufacturer/Marketer Address
463, 4 th Floor, RPG HOUSE, Dr. Annie Besant Road, Worli, Mumbai – 400 030. Maharashtra, INDIA
A licensed pharmacy from your nearest location will deliver Temotide 250mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your prescription and the availability of this medicine.
Best Price
₹4500
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5 tablets in 1 strip
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