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MD Pharmacology, MBBS
Last updated
16 Nov 2024 | 01:04 AM (IST)

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Tacrokan Lotion

Prescription Required

Product introduction

Tacrokan Lotion is used to treat eczema (atopic dermatitis). It works by suppressing the activity of certain immune cells that cause inflammation (redness and swelling) of the skin. This relieves itching and improves rashes in atopic dermatitis.

Tacrokan Lotion is used for external use. It should be used 2-4 times a day on the affected area or use it as suggested by the doctor. It should be applied slowly and evenly to the skin until it is rubbed in. You should not use it too often and you should not cover the treated area with a bandage or plaster. You must inform your doctor if there’s no improvement even after two weeks of treatment or if the skin gets worse.

Use of this medicine may cause some common side effects like erythema, headache, inflammation of hair follicle, and application site reaction like burning, irritation, itching, and redness. This medicine is not normally recommended during pregnancy or while breastfeeding unless it is clearly needed.

Uses of Tacrokan Lotion

Benefits of Tacrokan Lotion

In Treatment of Atopic dermatitis

Atopic dermatitis, also known as eczema, is a chronic skin condition causing red, itchy, and inflamed patches on the skin, often associated with allergies. Tacrokan Lotion when applied topically suppresses the immune response in the skin, reducing the inflammatory reactions that lead to eczema flare-ups. This way it provides relief and helps improve the quality of life for individuals with atopic dermatitis.

Side effects of Tacrokan Lotion

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Tacrokan

  • Application site reactions (burning, irritation, itching and redness)
  • Headache
  • Hair follicle inflammation

How to use Tacrokan Lotion

This medicine is for external use only. Use this medicine in the dose and duration as advised by your doctor. Shake it well and apply to the area evenly.

How Tacrokan Lotion works

Tacrokan Lotion is an immunosuppressant. It works by suppressing the activity of certain immune cells that cause inflammation (redness and swelling) of the skin. This relieves itching and improves rashes in atopic dermatitis.

Safety advice

Alcohol
No interaction found/established
Pregnancy
CONSULT YOUR DOCTOR
Tacrokan Lotion may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
Tacrokan Lotion is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
No interaction found/established
Kidney
No interaction found/established
Liver
No interaction found/established

What if you forget to take Tacrokan Lotion?

If you miss a dose of Tacrokan Lotion, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Tacrokan Lotion
₹155/Lotion
Tacrovin 0.03% Lotion
Galcare Pharmaceutical Pvt Ltd
₹264/lotion
65% costlier
₹180/lotion
12% costlier

Quick tips

  • Tacrokan Lotion is effective at treating eczema (atopic dermatitis) when other treatment options have failed.
  • It works by decreasing itching, redness, and skin rashes.
  • Apply thinly, to affected areas of skin only. Clean the affected area and dry well before applying Tacrokan Lotion. Avoid contact with water after application.
  • Inform your doctor if there's no improvement even after two weeks of treatment, or if the skin gets worse.
  • Don't cover the area being treated with airtight dressings such as bandages unless directed by a doctor, as this may increase the risk of side effects.
  • Stop using Tacrokan Lotion and consult your doctor if your eczema becomes infected.
  • Continuous long-term use of the ointment should be avoided. Use as prescribed by you doctor.

Fact Box

Chemical Class
Macrolide Lactams
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Immunosuppressant- Calcineurin inhibitors

Interaction with drugs

Taking Tacrokan with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Clarithromycin may decrease the metabolism of Tacrolimus. Talk to your doctor if you notice any unusual symptoms.
Clarithromycin may decrease the metabolism of Tacrolimus. Talk to your doctor if you notice any unusual symptoms.

Patient concerns

arrow
Suffering from Atopic dermatitis 15months baby suffering from atopic dermatitis
Dr. Gopal Bansilal Samdani
Paediatrics
Please consult skin specialist
Suffering from severe atopic dermatitis
Dr. Saurav Arora
Homeopathy
Dear sir atopic dermatitis needs supervision and regular follow up, therefore, you need to visit a homeopath personally
arrow

FAQs

What is Tacrokan Lotion used for?

Tacrokan Lotion is a medicine that modulates the immune system. It works on the immune system and mostly decreases its activity. It is used to treat moderate to severe eczema (atopic dermatitis) in adults who do not respond to steroids or develop side effects on using them. In atopic dermatitis, the skin’s immune system undergoes an overreaction and causes skin inflammation leading to itchiness, redness and dryness. Tacrokan Lotion acts on the abnormal immune response and alters it, thereby relieving the skin inflammation and itchiness.

What are the side effects of Tacrokan Lotion?

Tacrokan Lotion, when applied to the skin, may cause skin irritation, burning sensation and itching at the site of application. These are usually mild to moderate in severity and normally resolve within one week of starting the treatment. Redness is also a common manifestation along with sensation of warmth, pain, altered sensation and rash at the site of application. Using it increases the patients’ increased risk of getting inflamed or infected hair follicles, cold sores, acne and generalized herpes simplex infections.

Is Tacrokan Lotion ointment safe?

As compared to other immune-suppressing medicines, Tacrokan Lotion has been found to be a safe and effective short-term treatment for atopic dermatitis. When applied on the affected part of the skin, its absorption to the blood and body is minimal. Hence, the side effects are less as compared to when taken through oral route.

Does Tacrokan Lotion has abuse potential?

No, Tacrokan Lotion does not have abuse potential and thus, is not a controlled substance. Controlled substances have potential for abuse so they need permission by authorities and doctor for use.

Does Tacrokan Lotion cause cancer?

Long-term use of Tacrokan Lotion has been found to have increased risk of lymph node tumors called lymphoma. Some studies have found that few patients who used Tacrokan Lotion ointment or another similar medication developed skin cancer or lymphoma. Consult your doctor if you have to use Tacrokan Lotion ointment for more than 6 weeks or if your eczema symptoms have not improved or are getting worse with time during your treatment.

Is Tacrokan Lotion a steroid?

No, Tacrokan Lotion is not a steroid. It is a medicine which modulates the working of the immune system. It is used in the treatment of eczema, most commonly in atopic dermatitis. An advantage of Tacrokan Lotion is that it does not cause skin thinning (atrophy) or other steroid-related side effects.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Burkhart C, Morrell D, Goldsmith L. Dermatological Pharmacology. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1822.
  2. Lake DF, Briggs AD, Akporiaye ET. Immunopharmacology. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 972.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1305-309.
  4. Tacrolimus monohydrate. Hurley, Berkshire: Leo Laboratories Limited; 2002 [revised 30 Jun. 2018]. [Accessed 17 Apr. 2019] (online) Available from:External Link
  5. Central Drugs Standard Control Organisation (CDSCO). [Accessed 06 Apr. 2019] (online) Available from:External Link
  6. Tacrolimus [Prescribing Information]. Dublin 12, Ireland: LEO Laboratories Ltd.; 2022. [Accessed 01 Aug. 2023]. (online) Available from:External Link

Marketer details

Name: Future Dermacare Pvt Ltd
Address: PLot No. 105-C, Giriraj Nagar Govindpura Jaipur Jaipur RJ 302012 IN
Country of origin: India

155
Inclusive of all taxes
MRP160  3% OFF
20.0 ml in 1 bottle
SOLD OUT
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