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MRP: Rs. 410.36 for 1 tube(s) (10 GM ointment each)
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Composition for TACRODERM


food interaction for TACRODERM

alcohol interaction for TACRODERM

pregnancy interaction for TACRODERM

lactation interaction for TACRODERM

It can be taken with or without food, but it is better to take it at a fixed time.
Avoid it with high-fat meals such as olive oil, nuts & seeds (Brazil nuts), dark chocolate, butter and meat.
Interaction with alcohol is unknown. Please consult your doctor.
It may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The potential benefits may outweigh the risks. Please consult your doctor.
It is probably unsafe to use during breastfeeding. Please consult your doctor.




Tacroderm 0.1% ointment is used after transplantation of organs such as heart, liver, kidney or other organs so that the body does not reject the new organ. It is also used for certain skin diseases.

How it works

Tacroderm 0.1% ointment belongs to a category of drugs called as immunosuppressant. It prevents the body’s immune system from attacking the newly transplanted organ such as liver, heart, or kidney. This also helps in resolution of skin diseases due to altered immune function. 

Common side effects

Nausea, Liver enzyme increased, Abdominal bloating, Abdominal pain, Acne, Anemia, Anxiety, Convulsion, Cough, Cramps, Depression, Diarrhoea, Edema, Flatulence, Hair loss, Hallucination, Headache, Increased potassium level in blood, Increase in body weight, Indigestion, Insomnia, Itching, Mood changes, Muscle pain, Nasal congestion, Rash, Reduced blood platelets, Renal impairment, Ringing in ear, Tremor, Increased blood uric acid, Vascular disorder, Vision disorder, Weakness, Decreased white blood cell count


No substitutes found

Expert advice for TACRODERM

  • Take tacrolimus on empty stomach or 2-3 hours after a meal.
  • Do not take tacrolimus if you are allergic to it or to any other content in the medicine; or to sirolimus or other macrolide antibiotics (erythromycin, clarithromycin).
  • Doctor’s advice should be considered in case of patients with following history of disease conditions: liver problems, abnormal electrical signaling of the heart (QT interval prolongation), or diarrhea lasting for more than a day; abdominal pain, with or without vomiting, nausea, chills and fever.
  • Avoid using tacrolimus if you are pregnant or planning to become pregnant or breast-feeding a baby.
  • Limit exposure to the sun while taking the drug. Wear protective clothing and use sunscreen when stepping out in the sun, to prevent skin cancer.
  • Do not drive or operate heavy machinery while taking tacrolimus as it may cause dizziness.

Frequently asked questions for TACRODERM


Q. Is tacrolimus a steroid?
Tacrolimus is an immunosuppressant drug. It is not a steroid drug.
Q. Is tacrolimus nephrotoxic or cytotoxic?
Tacrolimus may cause destruction of certain types of cells (cytotoxic) and may impair kidney function (nephrotoxic). Patients should follow the advice of the doctor regarding its use.
Q. Is tacrolimus the same as Prograf?
Yes. Progarf is a branded form of tacrolimus available in the market.
Q. Is tacrolimus safe?
Yes. Tacrolimus is relatively safe if used as recommended. In case of any side-effects, consult your doctor.
Q. Can I take tacrolimus with omeprazole?
Omeprazole may increase the blood levels of tacrolimus. It can be taken with omeprazole only if prescribed by your doctor.
Q. Does tacrolimus cause diabetes, hair loss, tiredness, or depression?
Tacrolimus may cause diabetes, hair loss, tiredness, or depression. If you experience any such symptoms, please consult your doctor.


Content on this page was last updated on 11 February, 2016, by Dr. Varun Gupta (MD Pharmacology)