Tacrefite Eye Ointment

Reviewed By Dr. Rajeev Sharma, MBA, MBBS

Last updated on 21 Sep 2025 | 05:45 PM (IST)

Tacrefite Eye Ointment is a medicine used to treat allergic eye disease. It works by suppressing the immune response in the eye. Inhibiting specific immune cells activity reduces inflammation and symptoms such as itching, redness, and irritation.

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General Information

Contains

Tacrolimus (0.1% w/w)

Marketer

Austrak Pvt Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Tacrefite Eye Ointment decreases the production of inflammatory chemicals by certain immune cells (T lymphocytes) and relieves redness and swelling. Never use Tacrefite Eye Ointment if the seal is broken before you use it for the first time. Wash your hands before using it. Follow the instructions given by your doctor and use it in the dose and duration suggested by the doctor. Make sure you remove contact lenses if you wear them and wait for at least 15 minutes before putting them back. You must inform your doctor if there’s no improvement even after two weeks of treatment or if it gets worse.

The most common side effects of Tacrefite Eye Ointment include eye irritation and burning sensation. Let your doctor know if you experience any other symptoms which do not go away or get worse. Use of this medicine is not recommented in women who are pregnant or breastfeeding. Consult your doctor.

Uses of Tacrefite Eye Ointment

Treatment of Allergic eye disease

Benefits of Tacrefite Eye Ointment

Treatment of Allergic eye disease
Tacrefite Eye Ointment belongs to a group of medicines known as immunosuppressive agents. It helps relieve symptoms of allergic eye disease such as redness, swelling, itching, and watering of eyes. This medicine works by decreasing the production of certain chemicals that cause inflammation. This will make it easier for you to go about your daily activities. Use it as prescribed to get the most benefit. If you see no improvement even after 2 weeks, talk to your doctor.

Side effects of Tacrefite Eye Ointment

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Tacrefite

Eye irritation
Burning sensation

How to use Tacrefite Eye Ointment

This medicine is for external use only. Take it in the dose and duration as advised by your doctor. Check the label for directions before use. Hold the tube close to the eye without touching it. Gently squeeze the tube and place the medicine inside the lower eyelid.

How Tacrefite Eye Ointment works

Tacrefite Eye Ointment is an immunomodulator. It works by suppressing the action of a protein (calcineurin). This decreases the production of inflammatory chemicals by certain immune cells (T lymphocytes). This relieves allergic eye symptoms.

Quick tips

You have been prescribed Tacrefite Eye Ointment to treat inflammation (redness and swelling) due to allergies of the eye.
If you wear soft contact lenses, remove them before using Tacrefite Eye Ointment and wait at least 15 minutes before putting your lenses back in.
Do not touch the tip to any surface, or to your eye, to avoid contamination.
It may cause minor burning, stinging, or irritation in the eye. Inform your doctor if this does not go away.
Consult your doctor if your eye condition has not improved after two weeks of treatment or if it gets worse.
Continuous long-term use of the ointment should be avoided.

Safety advice

Alcohol

No interaction found/established

Pregnancy

CONSULT YOUR DOCTOR

Tacrefite Eye Ointment may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

SAFE IF PRESCRIBED

Tacrefite Eye Ointment is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving

UNSAFE

Tacrefite Eye Ointment may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

No interaction found/established

Liver

No interaction found/established

Interaction with drugs

Taking Tacrefite with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Moderate

Arsenic Trioxide (Injection Route)

Your doctor may monitor ECG (Electrocardiogram).

Frequently asked questions

Does Tacrefite Eye Ointment have an abuse potential?

No, Tacrefite Eye Ointment does not have abuse potential and thus, is not a controlled substance. Controlled substances have potential for abuse so they need permission from authorities and doctors for use.

What is Tacrefite Eye Ointment? What is it used for?

Tacrefite Eye Ointment belongs to a class of medicines known as immunosuppressant macrolides. It helps to relieve the symptoms of allergic eye disease such as pain, inflammation, redness and itching. Tacrefite Eye Ointment alters the abnormal immune response, relieves the inflammation and itching and also helps in preventing frequent flare-ups.

What are the side effects of Tacrefite Eye Ointment?

The most common side effects of Tacrefite Eye Ointment include eye irritation and burning sensation. However, these are usually not bothersome and resolve on their own. If any of these side effects worry you or persist for a longer duration, please consult your doctor.

How does Tacrefite Eye Ointment act?

Tacrefite Eye Ointment belongs to a class of medicines known as immunosuppressant macrolides. It works by suppressing the action of a protein (calcineurin) which decreases the production of inflammatory chemicals by certain immune cells (T lymphocytes). This relieves the allergic eye symptoms such as pain, redness, swelling and itching.

How to use Tacrefite Eye Ointment?

Remember to wash your hands before and after instilling Tacrefite Eye Ointment. Try not to touch your eye with the dropper or the tip of the ointment tube. Try to use it at about the same time each day. Use the prescribed number of drops or the right amount of ointment. Do not use more medicine or use more often than directed. Do not stop using Tacrefite Eye Ointment unless directed by your doctor and try not to miss any doses.

What other precautions should I take while using Tacrefite Eye Ointment?

If you wear soft contact lenses, remove them before using Tacrefite Eye Ointment. Wait for at least 15 minutes before putting your lenses back in. Do not touch the tip to any surface or your eye, to avoid contamination.

Fact Box

Chemical Class

Macrolide Lactams

Habit Forming

Therapeutic Class

OPHTHAL

Action Class

Calcineurin Inhibitors

References

Burkhart C, Morrell D, Goldsmith L. Dermatological Pharmacology. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1822.
Lake DF, Briggs AD, Akporiaye ET. Immunopharmacology. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 972.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1305-309.
Tacrolimus monohydrate. Camberley, Surrey: Sandoz Limited; 2010 [revised 27 Mar. 2017]. [Accessed 23 Jan. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 06 Apr. 2019] (online) Available from:
Erdinest N, Ben-Eli H, Solomon A. Topical tacrolimus for allergic eye diseases. Curr Opin Allergy Clin Immunol. 2019;19(5):535-543. [Accessed 07 Aug. 2023]. (online) Available from:

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Austrak Pvt Ltd
Address: Austrak House, Plot No : 2/9, S.S.S. Nagar, West Marredpally, Hyderabad-500026.

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Provide right medicines

Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose

In accordance with the law

Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945

Tacrefite Eye Ointment

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Tacrefite Eye Ointment

Benefits of Tacrefite Eye Ointment

Side effects of Tacrefite Eye Ointment

How to use Tacrefite Eye Ointment

How Tacrefite Eye Ointment works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Arsenic Trioxide (Injection Route)

Frequently asked questions

Does Tacrefite Eye Ointment have an abuse potential?

What is Tacrefite Eye Ointment? What is it used for?

What are the side effects of Tacrefite Eye Ointment?

How does Tacrefite Eye Ointment act?

How to use Tacrefite Eye Ointment?

What other precautions should I take while using Tacrefite Eye Ointment?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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