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Syndopa Plus Tablet is a combination of two medicines used to treat Parkinson’s disease. It is one of the most effective medications to relives symptoms of Parkinson’s disease such as tremors, muscle stiffness, and difficulty moving.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 29 Apr 2026 | 01:01 PM (IST)
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Syndopa Plus Tablet image
Syndopa Plus Tablet image
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Syndopa Plus Tablet image

Product introduction

Syndopa Plus Tablet can be taken without food but it is better to avoid a high protein diet and dairy products while taking this medicine. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration advised by your doctor and if you have missed a dose, take it as soon as you remember it. You should never skip any doses and try to finish the full course of treatment even if you feel better. Do not stop taking medicine until told by your doctor as it can cause harmful effects.

This medicine may cause side effects like nausea, vomiting, dryness in the mouth, sweating, and headache. Initially, this medicine may cause a sudden drop in blood pressure when you change positions, so it's better to rise slowly if you have been sitting or lying down. It causes a sudden onset of dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you.

Take caution while taking medicine if you are suffering from liver or kidney disease. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding.

Uses of Syndopa Tablet

Benefits of Syndopa Tablet

Treatment of Parkinson's disease
Syndopa Plus Tablet is one of the most effective medications to relieve symptoms of Parkinson's disease such as tremors, muscle stiffness, and difficulty moving. It increases the amount of a chemical called dopamine in the brain which helps in the coordination of body movements. This medicine can therefore enhance the quality of life by improving the ability to carry out daily functions in a better manner.

Side effects of Syndopa Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Syndopa
  • Involuntary muscle movement
  • Gastrointestinal disturbance
  • Dryness in mouth
  • Dizziness
  • Headache
  • Abnormal dreams
  • Sweating

How to use Syndopa Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Syndopa Plus Tablet is to be taken on an empty stomach.
Avoid Syndopa Plus Tablet with high protein meals such as cottage cheese, Swiss cheese, protein powder, eggs and milk.

How Syndopa Tablet works

Syndopa Plus Tablet is a combination of two medicines: Levodopa and Carbidopa which treats Parkinsonism. Levodopa is a dopamine precursor which gets converted to dopamine, a chemical messenger that controls movement in the brain. Carbidopa is a peripheral decarboxylase inhibitor which prevents breakdown of levodopa, allowing it to enter the brain and increase dopamine levels.

All substitutes for Syndopa Plus Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

  • You have been prescribed Syndopa Plus Tablet to treat your symptoms of Parkinson's disease.
  • Reduce/avoid a high-protein diet (e.g. meat, poultry, and dairy products) while you are taking the medicine as it can reduce the amount of medication absorbed by your body.
  • Be cautious while driving or doing anything that requires concentration as Syndopa Plus Tablet can make you very sleepy.
  • When you start the medication, get out of bed slowly, as the medication may cause dizziness, lightheadedness or fainting.
  • Do not stop taking the medication without talking to your doctor. It may result in a serious syndrome that causes fever, stiff muscles, unusual body movements, sweating, and confusion.
  • Talk to your doctor in case you develop hallucinations or other changes in your behavior.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Syndopa Plus Tablet. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Syndopa Plus Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

UNSAFE
Syndopa Plus Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving

Driving

UNSAFE
Syndopa Plus Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Syndopa Plus Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Liver

Liver

CAUTION
Syndopa Plus Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.

Frequently asked questions

Syndopa Plus Tablet is a combination of two medicines: Levodopa and Carbidopa. This medication is used to treat the symptoms of Parkinson's disease like tremors (shaking), stiffness and slowness of movement. These symptoms are caused due to the lack of dopamine, a natural substance usually found in the brain. Levodopa works by being converted to dopamine in the brain. Carbidopa works by preventing levodopa from being broken down before it reaches the brain. By increasing the amount of dopamine in the brain, Syndopa Plus Tablet helps control the symptoms of Parkinson’s disease and helps you to perform daily activities such as dressing, walking, handling utensils, etc.
No, you should continue to take Syndopa Plus Tablet, even if you feel well. Do not stop taking Syndopa Plus Tablet without talking to your doctor. If you suddenly stop taking Syndopa Plus Tablet, you could develop a serious problem causing fever, rigid muscles, unusual body movements and confusion. Consult your doctor if the symptoms are relieved, he might decrease your dose gradually.
Syndopa Plus Tablet may make you drowsy or may cause you to suddenly fall asleep during your daily activities. You might not feel drowsy or notice any other warning signs before suddenly falling asleep. Avoid driving a car, operating machinery, working at heights or participating in potentially dangerous activities at the beginning of your treatment until you know how the medication affects you. If you suddenly fall asleep while doing something such as watching television, talking, eating, or riding in a car, or if you become very drowsy, especially during the daytime, call your doctor.
Yes, it is a rare side effect. Consumption of Syndopa Plus Tablet may alter the colour of your saliva, urine or sweat and make it dark colored (red, brown or black). This is harmless but your clothing may become stained.
Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
Syndopa Plus Tablet controls Parkinson's disease but does not cure it. It may take several months before you feel the full benefit of Syndopa Plus Tablet.

Fact Box

Habit Forming

No

Therapeutic Class

NEURO CNS

References

  1. Carbidopa/Levodopa [Summary of Product Characteristics]. Hamburg, Germany: Fairmed Healthcare GmbH; 2024.
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User feedback

Once A Day
100%
Parkinson's disease
90%
Others
10%
Average
50%
Poor
26%
Excellent
24%
No Side Effect
35%
Constipation
22%
Dryness in mouth
22%
Dizziness
9%
Nausea
9%
With food
45%
With or without food
35%
Empty stomach
20%
Not Expensive
47%
Expensive
28%
Average
25%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Sun Pharmaceutical Industries Ltd
Address: Plot no 107/108,Namli block , Ranipool, East Sikkim 737135 || Khasra No. 1335-1340,Near EPIP- I, Vill - Bhatoli Kalan ,Baddi, Solan, Himachal Pradesh, 173205 || Acme Plaza, Andheri-Kurla Road, Andheri (East), Mumbai, Maharashtra -400059

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Syndopa Plus Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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