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Syndopa CR 125 Tablet

Prescription Required

Overview

Introduction

Syndopa CR 125 Tablet is a combination of two medicines used to treat Parkinson’s disease. It is one of the most effective medications to relives symptoms of Parkinson’s disease such as tremor, muscle stiffness and difficulty moving.

Syndopa CR 125 Tablet can be taken without food but it is better to avoid high protein diet and dairy products while taking this medicine. However, it is advised to take it at the same time each day as this helps to maintain consistent level of medicine in the body. Take this medicine in the dose and duration advised by your doctor and if you have missed a dose, take it as soon as you remember it. You should never skip any doses and try to finish the full course of treatment even if you feel better. Do not stop taking medicine until told by your doctor as it can cause harmful effects.

This medicine may cause side effects like nausea, vomiting, dryness in mouth, constipation, and headache. Initially, this medicine may cause a sudden drop in blood pressure when you change positions, so it's better to rise slowly if you have been sitting or lying down. It causes a sudden onset of dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you.

Take caution while taking medicine if you are suffering from liver or kidney disease. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Uses of Syndopa Tablet PR

Side effects of Syndopa Tablet PR

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Syndopa

  • Nausea
  • Vomiting
  • Dryness in mouth
  • Constipation
  • Dizziness
  • Sleepiness
  • Headache
  • Abnormal dreams
  • Anxiety
  • Insomnia (difficulty in sleeping)
  • Abnormality of voluntary movements
  • Orthostatic hypotension (sudden lowering of blood pressure on standing)

How to cope with side effects?

The occurrence of side effects varies from person to person. The following are a few ways of dealing with some of the common side effects. However, consult your doctor if these persist.

  • Coping with Nausea
    You can help yourself by eating small, frequent meals rather than large ones and drinking plenty of fluids. Eat slowly. Avoid fatty, fried, spicy and very sweet foods. Eat cold or slightly warm food if the smell of cooked or cooking food makes you feel sick. Get plenty of fresh air. You could also try chewing ginger or drinking ginger tea. Eat bananas to replace potassium in your blood which can drop if you are sick (vomit). Use oral rehydration salts to replace vitamins and minerals lost through being sick. There are some medicines that can help you stop from feeling sick. Speak to your doctor if your condition does not improve.
  • Coping with Vomiting
    You can help yourself by eating small, frequent meals rather than large ones and drinking plenty of fluids. Eat slowly. Avoid fatty, fried, spicy and very sweet foods. Eat cold or slightly warm food if the smell of cooked or cooking food makes you feel sick. Get plenty of fresh air. You could also try chewing ginger or drinking ginger tea. Eat bananas to replace potassium in your blood which can drop if you are sick (vomit). Use oral rehydration salts to replace vitamins and minerals lost through being sick. There are some medicines that can help you stop feeling sick. Speak to your doctor if your condition does not improve.
  • Coping with Dryness in mouth
    Keep a drink available that you can sip through the day. Rinse your mouth with warm salted water and chew sugarless gum or hard candy. Try breathing through your nose more often than your mouth. Avoid caffeinated beverages, smoking and alcohol because they can make your condition worse. Use lip balm if your lips are also dry. Try to avoid foods that are acidic (like lemons), spicy, salty or sugary. If this side effect bothers you or does not go away, talk to your doctor about artificial saliva products or other suitable treatments.
  • Coping with Constipation
    Try to eat foods which are high in fiber such as fresh fruits, vegetables and cereals to increase the bulk and consistency of bowel movements. Drink plenty of water or non-alcoholic drinks and stay hydrated to promote healthy digestion. Increasing physical activities such as walking, yoga and regular exercise can also be helpful. If your condition does not improve, you can ask your doctor to prescribe you laxative medicine.
  • Coping with Dizziness
    This is usually short-lived and should go away within a few days. If this happens, stop what you are doing and sit or lie down until you feel better. Lying still in a dark, quiet room may help reduce the spinning feeling. Sleep with your head slightly raised on two or more pillows. Get up slowly from a lying or sitting position. Get plenty of rest and try to relax as being anxious can make it worse. Try taking this medicine at bedtime to reduce the symptoms. Drinking plenty of water and ginger tea may also help. Avoid alcohol, caffeine and smoking as it will make you feel worse. Avoid driving or using tools or machinery until you feel better.
  • Coping with Sleepiness
    If the medicine is making you drowsy during the day, stop what you are doing and sit or lie down until you feel better. You can also consider taking a nap. Physical exercises such as walking may be helpful. Do not drink alcohol, as it will make you feel more tired. Avoid driving or operating heavy equipment when you are feeling drowsy. This problem usually goes away as your body gets used to the medicine. However, if it does not, ask your doctor if you can take your medicine at bedtime or whether the dose can be reduced.
  • Coping with Headache
    Make sure you rest and drink plenty of fluids. Rest in a quiet, dimly lit room. Do not sleep more than you normally would. Do not strain your eyes (for example by looking at a screen). Do not drink alcohol. Headaches are usually temporary and usually go away with time. But, if they last longer or get worse, ask your doctor to recommend a painkiller.
  • Coping with Abnormal dreams
    Try taking your medicine in the morning. If you have to take it more than once a day, speak to your doctor. To help yourself, try to go to bed and get up at the same time each day and reduce naps. Do some light exercise each day to tire yourself. Make sure the room is not too hot or too cold. Relax before bedtime by taking a bath or listening to music. Don't go to bed hungry. Try using earplugs. Meditation, deep breathing and relaxation exercises can also help. Talk to your doctor if you have tried these tips and they have not helped.
  • Coping with Anxiety
    This often disappears when the condition you are being treated for is managed. You could ask your doctor about changing the dose of your medicine or alternatives if it is affecting your daily life or causing you distress. Psychological treatments may be available. Some things you can do to help yourself include stopping smoking, cutting down the amount of alcohol and caffeine you drink, and doing regular exercise. You should also eat a healthy diet and find out how to get sleep if you are having trouble. Try talking to a friend or family member. Calming breathing exercises and other relaxation techniques may also help.

How to use Syndopa Tablet PR

Use it as advised by your doctor or check the label for directions before use. Syndopa CR 125 Tablet is to be taken empty stomach.
Avoid Syndopa CR 125 Tablet with high protein meals such as cottage cheese, Swiss cheese, protein powder, eggs and milk.

How Syndopa Tablet PR works

Syndopa CR 125 Tablet is a combination of two medicines: Levodopa and Carbidopa which treats Parkinsonism. Levodopa is a dopamine precursor which gets converted to dopamine, a chemical messenger that controls movement in the brain. Carbidopa is a peripheral decarboxylase inhibitor which prevents breakdown of levodopa allowing it to enter the brain and increase dopamine levels.

Safety Advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Syndopa CR 125 Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Syndopa CR 125 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breastfeeding
SAFE IF PRESCRIBED
Syndopa CR 125 Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Partial to complete suppression of lactation was seen in mothers on the treatment with Syndopa CR 125 Tablet, but when the treatment was stopped, lactation returned to normal levels.
Driving
UNSAFE
Syndopa CR 125 Tablet may cause side effects which could affect your ability to drive.
As Syndopa CR 125 Tablet may cause dizziness, drowsiness, double vision, which may affect your ability to react which may affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Syndopa CR 125 Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Syndopa CR 125 Tablet may not be needed in these patients. Please consult your doctor.
Liver
CAUTION
Syndopa CR 125 Tablet should be used with caution in patients with liver disease. Dose adjustment of Syndopa CR 125 Tablet may be needed. Please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
No alternate brands found for this medicine

Quick Tips

  • You have been prescribed Syndopa CR 125 Tablet to treat your symptoms of Parkinson's disease.
  • It can be taken with or without food or as directed by your doctor.
  • Reduce/avoid a high-protein diet (e.g. meat, poultry, and dairy products) while you are taking the medicine as it can reduce the amount of medication absorbed by your body.
  • Be cautious while driving or doing anything that requires concentration as Syndopa CR 125 Tablet can make you very sleepy.
  • When you start the medication, get out of bed slowly, as the medication may cause dizziness, lightheadedness or fainting.
  • Do not stop taking the medication without talking to your doctor. It may result in a serious syndrome that causes fever, stiff muscles, unusual body movements, sweating, and confusion.
  • Talk to your doctor in case you develop hallucinations or other changes in your behavior.

Fact Box

Habit Forming
No

Patient Concerns

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treatment for Parkinson's disease taking now syndopa cr 125, raslect n other medicine isn't this disease fully curable pls help n give u r opinion
Dr. Ravindra Srivastava
Neuro Surgery
MEDICINE CONTROLS THE SYMTOMS. IF MEDICINES FAIL TO CONTROL THE DEEP BRAIN STIMULATION SURGERY IS BEING DONE.
Sir my father diagonosed parkinson plus disease ,having stiffness in all joints and bedridden .Moreover both femur bone operated and having plate since2014.kindly suggest treatment
Dr. Vikas Sharma
Neurology
Tab syndopa half tab thrice a day Physiotherapy
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Do you have any questions related to Syndopa CR 125 Tablet ?

User Feedback


FAQs

Q. What is Syndopa?

Syndopa is a combination of two medicines: Levodopa and Carbidopa. This medication is used to treat the symptoms of Parkinson's disease like tremors (shaking), stiffness and slowness of movement. These symptoms are caused due to the lack of dopamine, a natural substance usually found in the brain. Levodopa works by being converted to dopamine in the brain. Carbidopa works by preventing levodopa from being broken down before it reaches the brain. By increasing the amount of dopamine in the brain, Syndopa helps control the symptoms of Parkinson’s disease and helps you to perform daily activities such as dressing, walking, handling utensils, etc.

Q. Can I stop taking Syndopa when my symptoms are relieved?

No, you should continue to take Syndopa, even if you feel well. Do not stop taking Syndopa without talking to your doctor. If you suddenly stop taking Syndopa, you could develop a serious problem causing fever, rigid muscles, unusual body movements and confusion. Consult your doctor if the symptoms are relieved, he might decrease your dose gradually.

Q. Can the Syndopa cause sleepiness or drowsiness?

Syndopa may make you drowsy or may cause you to suddenly fall asleep during your daily activities. You might not feel drowsy or notice any other warning signs before suddenly falling asleep. Avoid driving a car, operating machinery, working at heights or participating in potentially dangerous activities at the beginning of your treatment until you know how the medication affects you. If you suddenly fall asleep while doing something such as watching television, talking, eating, or riding in a car, or if you become very drowsy, especially during the daytime, call your doctor.

Q. Can the Syndopa cause dark urine?

Yes, the consumption Syndopa may alter the colour of your saliva, urine or sweat and make it dark colored (red, brown or black). This is harmless but your clothing may become stained.

Q. What are the instructions for storage and disposal of Syndopa?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Q. How long does Syndopa take to cure Parkinson’s disease?

Syndopa controls Parkinson's disease but does not cure it. It may take several months before you feel the full benefit of Syndopa.

Q. Can I take a higher than the recommended dose of this medication?

No, taking a higher than the recommended dose of Syndopa can lead to increased chances of side effects and toxicity. Talk to your doctor if your symptoms do not improve after a few weeks of treatment. Also let your doctor know if the effects of this medication seem to wear off quickly in between doses.

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Disclaimer:

1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. MedlinePlus. Levodopa + Carbidopa. [Accessed 23 Apr. 2019] (online) Available from:External Link
  2. MedIndia. Levodopa+Carbidopa. [Accessed 23 Apr. 2019] (online) Available from:External Link
  3. Carbidopa and Levodopa. Harrow, UK: Accord Healthcare Limited; 2014. [Accessed 26 Apr. 2019] (online) Available from:External Link

Manufacturer/Marketer Address

90, Delhi - Jaipur Road, Sector 32, Gurugram, Haryana 122001
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