Syncapone 50 Tablet


Introduction

Syncapone 50 Tablet is a prescription medicine used in the treatment of Parkinson's disease. This medicine helps to reduce excessive shaking by slowing down the body movements. It works by increasing the amount of chemical messenger that is needed to control abnormal movements.

Syncapone 50 Tablet is taken with or without food, but better to avoid high protein meal and dairy products. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration advised by your doctor and if you have missed a dose, take it as soon as you remember. You should never skip any doses and try to finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to the doctor as it can result in harmful effects.

This medicine may cause side effects like nausea, vomiting, constipation, discoloration of urine, and dryness in the mouth. It causes a sudden onset of dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you.  It is common to have diarrhea with this medicine, so drink plenty of fluids and watch for weight loss.

Take caution while taking medicine if you are suffering from liver or kidney disease. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Uses of Syncapone Tablet

Benefits of Syncapone Tablet

In Parkinson's disease

Syncapone 50 Tablet is a medicine that helps relieve symptoms of Parkinson's disease such as tremors, muscle stiffness and difficulty moving. It increases the amount of a chemical called dopamine in the brain which helps in coordination of body movements. This medicine can therefore enhance the quality of life by improving the ability to carry out daily functions in a better manner.

Side effects of Syncapone Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Syncapone

  • Nausea
  • Vomiting
  • Constipation
  • Urine discoloration
  • Headache
  • Dryness in mouth
  • Insomnia (difficulty in sleeping)
  • Orthostatic hypotension (sudden lowering of blood pressure on standing)
  • Anxiety
  • Dizziness
  • Abnormality of voluntary movements
  • Abnormal dreams

How to use Syncapone Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Syncapone 50 Tablet may be taken with or without food, but it is better to take it at a fixed time.
Avoid Syncapone 50 Tablet with high protein meals such as cottage cheese, Swiss cheese, protein powder, eggs and milk.

How Syncapone Tablet works

Syncapone 50 Tablet is a combination of three medicines: Levodopa, Carbidopa and Entacapone which treat Parkinsonism. Levodopa is a Carbidopa precursor which gets converted to dopamine, a chemical messenger that controls movement in the brain. Carbidopa is a peripheral decarboxylase inhibitor which prevents the breakdown of Levodopa allowing it to enter the brain and increase dopamine levels. Entacapone is COMT inhibitor which causes higher and more sustained levels of levodopa in blood, leading to greater relief from the symptoms of Parkinson’s disease.

Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Syncapone 50 Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Syncapone 50 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Syncapone 50 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Syncapone 50 Tablet may cause side effects which could affect your ability to drive.
Caution is advised when driving or operating machinery.
Kidney
SAFE IF PRESCRIBED
Syncapone 50 Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Syncapone 50 Tablet may not be needed in these patients. Please consult your doctor.
Liver
CAUTION
Syncapone 50 Tablet should be used with caution in patients with liver disease. Dose adjustment of Syncapone 50 Tablet may be needed. Please consult your doctor.

What if you forget to take Syncapone Tablet?

If you miss a dose of Syncapone 50 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate brands

For informational purposes only. Consult a doctor before taking any medicines.
Syncapone 50 Tablet
₹9.2/Tablet
Tidomet E 50mg/12.5mg/200mg Tablet
Torrent Pharmaceuticals Ltd
₹4.83/tablet
48% cheaper
₹5.36/tablet
42% cheaper
Entacom Plus 50 Tablet
Intas Pharmaceuticals Ltd
₹8.95/tablet
3% cheaper

Quick tips

  • You have been prescribed Syncapone 50 Tablet to treat your symptoms of parkinson's disease.
  • Avoid a high-protein diet (eg.meat, poultry, and dairy products) while you are taking this medicine as that can reduce the amount of medication absorbed by your body. 
  • It may cause dizziness or sleepiness. Don't drive or do anything requiring concentration until you know how it affects you.
  • To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
  • Do not stop taking the medication suddenly without talking to your doctor. It may result in a serious syndrome that causes fever, stiff muscles, unusual body movements, sweating and confusion.
  • Talk to your doctor in case you develop hallucinations or notice other changes in your behavior.

Fact Box

Habit Forming
No
Therapeutic Class
NEURO CNS

Patient concerns

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Parkinson's disease tremors ,Insomnia.
Dr. Ravi Shankar M.
Ayurveda
Use Dhanadanayanadi kashayam 15ml twice a day with 15 ml water before food and Zandopa 10 grams twice a day witk milk after food and Tab Dhanvantari Vati 1-0-1 after food for 2 months
Parkinson's disease for 25 yrs. Taking allopathy Suggestions needed
Dr. Deepak Kumar Soni
Ayurveda
Kindly consult to any good Ayuvedic Panchkarma center. Panchkarma therapy will give you some result .
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1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. European Medicine Agency. Levodopa+Carbidopa+Entacapone Sandoz; 2014. [Accessed 23 Apr. 2019] (online) Available from:External Link
  2. Levodopa+Carbidopa+Entacapone. Espoo, Finland: Orion Corporation; 2010. [Accessed 23 Apr. 2019] (online) Available from:External Link

Manufacturer/Marketer address

90, Delhi - Jaipur Road, Sector 32, Gurugram, Haryana 122001
Country of origin: India

Expires on or after: October, 2021

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