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Sugmadex 500mg Injection

Sugammadex (100mg/ml)
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Sugmadex 500mg Injection is a medicine that is used to reverse the effects of some drugs in a patient undergoing surgery in a hospital setup.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 08 Aug 2026 | 01:09 AM (IST)
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5 ml Injection
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Gurgaon
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Sugmadex 500mg Injection image
Sugmadex 500mg Injection image

Product introduction

Sugmadex 500mg Injection is given by a trained healthcare professional during the surgery as a single bolus injection. The patient should be monitored and proper ventilation should be maintained.

Some of the common side effects of this medicine include vomiting, pain, nausea, hypotension, and headache. Let the doctor know if these bother you or do not resolve.

Inform the doctor if you are suffering from any disease related to the heart, kidneys, lungs, or if you are taking any medicines regularly. Pregnant or breastfeeding women should not use this medicine unless advised by the doctor.

Uses of Sugmadex Injection

  • Reversing the effects of certain drugs used during surgery

Benefits of Sugmadex Injection

Reversing the effects of certain drugs used during surgery
Sugmadex 500mg Injection is a medicine given by a doctor to reverse the effects of some medicines in a patient during an ongoing surgery. It is given as an injection and should be used only under the supervision of a healthcare expert.

Side effects of Sugmadex Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Sugmadex
  • Vomiting
  • Pain
  • Nausea
  • Hypotension (low blood pressure)
  • Headache

How to use Sugmadex Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Sugmadex Injection works

Sugmadex 500mg Injection binds to the specific muscle relaxants (vecuronium and rocuronium) forming a ‘complex’ that inactivates these muscle relaxants and prevents them showing an effect. Consequently, the muscles contract and begin to work normally again.

All substitutes for Sugmadex 500mg Injection

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

  • If you have been taking contraceptive pills, consider additional, non-hormonal methods of contraception (condoms) for the next 7 days following Sugmadex 500mg Injection administration to avoid getting pregnant.
  • Inform your doctor if you have liver or kidney disorders prior to administration of this medicine.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Sugmadex 500mg Injection. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Information regarding the use of Sugmadex 500mg Injection during pregnancy is not available. Please consult your doctor.
Breast feeding

Breast feeding

CAUTION
Sugmadex 500mg Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Sugmadex 500mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney

Kidney

CAUTION
Sugmadex 500mg Injection should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Liver

Liver

CAUTION
Sugmadex 500mg Injection should be used with caution in patients with severe liver disease. Dose adjustment may be needed.
All

Interaction with drugs

Taking Sugmadex with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Mild

Enoxaparin (Injection Route)

Your doctor may monitor the treatment outcome and may modify the treatment protocol as per the observation.
Mild

Enoxaparin (Oral Route)

Your doctor may monitor the treatment outcome and may modify the treatment protocol as per the observation.
Mild

Heparin (Injection Route)

Your doctor may monitor the treatment outcome and may modify the treatment protocol as per the observation.
Mild

Allylestrenol (Oral Route)

Talk to your doctor if you notice any unusual symptoms. Sugammadex may reduce blood levels of Allylestrenol.
Mild

Centchroman (Oral Route)

Talk to your doctor if you notice any unusual symptoms. Sugammadex may reduce blood levels of Centchroman.

Frequently asked questions

Sugmadex 500mg Injection is indicated for the reversal of neuromuscular blockade induced by rocuronium bromide and vecuronium bromide in patients aged 2 years and older undergoing surgery.
Although rare, Sugmadex 500mg Injection can cause serious allergic reactions in some people. Symptoms can show up within 5 minutes of getting Sugmadex 500mg Injection, and can include redness and swelling of the eyes, and throat, skin redness, difficulty breathing. Other, less serious symptoms of an allergic reaction, can include nausea, itching, and rash.
Sugmadex 500mg Injection may reduce the contraceptive effect of birth control pills. It is advisable to use effective oral contraceptive pills during and for 7 days after the administration of Sugmadex 500mg Injection to avoid getting pregnant.
No, Sugmadex 500mg Injection is not recommended for use in patients with severe renal impairment, including those requiring dialysis.

Fact Box

Chemical Class

Oligosaccharides

Habit Forming

No

Therapeutic Class

NEURO CNS
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Varenyam Healthcare Pvt Ltd
Address: 2, Vitrag Appartment, Karelibaug, Vadodara-390018, Gujarat, INDIA

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Sugmadex 500mg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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