Sofrazen 0.5% Cream

Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS

Last updated on 25 Nov 2025 | 03:05 PM (IST)

Sofrazen 0.5% Cream is an antibiotic used to treat bacterial skin infections. It is effective in treating infected cuts, wounds, and minor burns. This medicine stops the bacteria from growing, which helps to resolve your symptoms and cure the underlying infection.

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General Information

Storage

Store below 30°C

The content is shown in English

Product introduction

Sofrazen 0.5% Cream is meant for external use only. It should be applied only to the affected area of the skin as per the dosage and schedule prescribed by your doctor. To get the most benefit, apply it regularly and preferably at a fixed time each day. Do not use larger amounts or apply it more often or for a longer duration than directed. This will only increase the risk of side effects.

Local side effects like minor burning, irritation, itching, and redness may be seen after the application of this medicine. These side effects are temporary and resolve quickly. Consult your doctor if these persist or if your condition does not improve.

Avoid any contact with your eyes, nose, or mouth. Rinse off any accidentally exposed area with water. Before using it, inform your doctor if you have any previous history of allergy to it or any other medicine. Pregnant or breastfeeding women should consult their doctor before using it.

Uses of Sofrazen Cream

Bacterial skin infections

Benefits of Sofrazen Cream

Bacterial skin infections
Sofrazen 0.5% Cream is an antibiotic that works by stopping the growth of infection-causing bacteria on your skin. It prevents the synthesis of essential proteins necessary for the survival of bacteria. It is effective against skin infections such as boils, impetigo, and infected hair follicles. It may also be used to treat infections in small cuts or wounds on your skin. This treatment has few common side effects and should clear up infections within a few days, but you should keep using it for as long as it is prescribed.

Side effects of Sofrazen Cream

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Sofrazen

Application site reactions (burning, irritation, itching and redness)

How to use Sofrazen Cream

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the cream. Wash your hands after applying, unless hands are the affected area.

How Sofrazen Cream works

Sofrazen 0.5% Cream is an antibiotic. It stops bacterial growth by preventing synthesis of essential proteins required by bacteria to carry out vital functions.

Quick tips

You have been prescribed Sofrazen 0.5% Cream for the treatment of bacterial skin infections.
It should be applied to the affected areas as a thin film, two or three times daily, or as advised by your doctor.
Don't use it more often or for longer than advised by your doctor. Inform your doctor if your skin problem hasn't improved after seven days of treatment.
Don't apply it to broken skin and avoid getting it in your eyes, nose or mouth.
Don't cover the area being treated with airtight dressings such as bandages unless directed by a doctor, as this may increase the risk of side effects.
It may cause temporary burning, itching or a redness at application site. This is usually mild. Consult your doctor if you experience a more severe reaction.

Safety advice

Alcohol

No interaction found/established

Pregnancy

CONSULT YOUR DOCTOR

The safety of Sofrazen 0.5% Cream during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

SAFE IF PRESCRIBED

Sofrazen 0.5% Cream may be safe to use during breastfeeding. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
The baby's skin should not come into direct contact with the treated area of skin. Water-miscible cream/gel is preferred as ointments may expose the baby to harmful effects of Sofrazen 0.5% Cream via licking.

Driving

No interaction found/established

Kidney

No interaction found/established

Liver

No interaction found/established

Interaction with drugs

Taking Sofrazen with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Moderate

Vitamin A (Injection Route)

Talk to your doctor if you notice any unusual symptoms. Vitamin A may raise blood levels of the active form of Neomycin.

Moderate

Vitamin A (Oral Route)

Talk to your doctor if you notice any unusual symptoms. Vitamin A may raise blood levels of the active form of Neomycin.

Frequently asked questions

What is Sofrazen 0.5% Cream? What is it used for?

Sofrazen 0.5% Cream is an antibiotic used to treat bacterial skin infections. It may also be used to treat infected cuts and wounds. Sofrazen 0.5% Cream stops the bacteria from growing, which helps to resolve the symptoms.

Is Sofrazen 0.5% Cream effective?

Sofrazen 0.5% Cream is effective if used in the dose and duration advised by your doctor. Do not stop taking it even if you see improvement in your condition. If you stop using Sofrazen 0.5% Cream too early, the symptoms may return or worsen.

How to use Sofrazen 0.5% Cream?

Before using Sofrazen 0.5% Cream, clean and dry the affected area. Gently and thoroughly massage it into the skin. Be careful not to get the medication in your eyes or mouth. If Sofrazen 0.5% Cream gets in your eyes accidentally, wash with plenty of water and call your doctor if your eyes are irritated.

What precautions do I need to take while using Sofrazen 0.5% Cream?

Be careful not to get Sofrazen 0.5% Cream into your eyes or mouth. If you happen to get it in your eyes, rinse off with plenty of water immediately and contact your doctor. You must not use Sofrazen 0.5% Cream if you are allergic to it or any of its ingredients. Tell your doctor if you notice any allergic reaction while using it for the first time. Inform your doctor if you are taking any medicines regularly to prevent any allergic reaction with other medicines. Do not cover the area being treated with Sofrazen 0.5% Cream with a bandage, as this may increase absorption of this medicine and increase the side effects. Do not use more than what is recommended to relieve your symptoms faster. Using more than what is advised will only increase the side effects. Let your doctor know if you are planning to conceive. Pregnant and breastfeeding mothers should use Sofrazen 0.5% Cream only if prescribed by the doctor.

What should I do if I forget to use Sofrazen 0.5% Cream?

If you forget to use Sofrazen 0.5% Cream, do not worry and continue using Sofrazen 0.5% Cream as soon as you remember. However, if you are not sure and have any other doubts, please consult your doctor.

Is Sofrazen 0.5% Cream safe?

Sofrazen 0.5% Cream is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.

Fact Box

Chemical Class

Aminoglycosides

Habit Forming

Therapeutic Class

DERMA

Action Class

Bacterial Protein Synthesis Inhibitors- Aminoglycosides

Related lab tests

Complete Blood Count

References

MacDougall C, Chambers HF. Aminoglycosides. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1518.
Chambers HF, Deck DH. Aminoglycosides & Spectinomycin. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 813.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 968.
ScienceDirect. Neomycin. [Accessed 31 Mar. 2019] (online) Available from:
PubChem. Neomycin. [Accessed 31 Mar. 2019] (online) Available from:

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Zen Labs India
Address: Plot No. 194-195, 3rd Floor, Industrial Area, Phase-II, Chandigarh (India) - 160002

Vendor Details

Country of origin: India

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Why we need a prescription?

Provide right medicines

Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose

In accordance with the law

Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945

Sofrazen 0.5% Cream

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General Information

Contains

Salt Synonyms

Marketer

Storage

Product introduction

Uses of Sofrazen Cream

Benefits of Sofrazen Cream

Side effects of Sofrazen Cream

How to use Sofrazen Cream

How Sofrazen Cream works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Vitamin A (Injection Route)

Vitamin A (Oral Route)

Frequently asked questions

What is Sofrazen 0.5% Cream? What is it used for?

Is Sofrazen 0.5% Cream effective?

How to use Sofrazen 0.5% Cream?

What precautions do I need to take while using Sofrazen 0.5% Cream?

What should I do if I forget to use Sofrazen 0.5% Cream?

Is Sofrazen 0.5% Cream safe?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Complete Blood Count

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests