Simezan-D Tablet ER
Prescription Required
View available alternative with same salt composition
Product introduction
Simezan-D Tablet ER is a combination medicine that helps control blood sugar levels. This medicine is used with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. It helps in the proper utilization of insulin, thereby lowering the blood sugar level.
Simezan-D Tablet ER can be taken with or without food at any time of the day, but try to take it at the same time every day. The dose will be decided by your doctor, so do not stop taking it without asking them. If you do, your blood sugar levels may increase your risk of serious complications like kidney damage and blindness. This medicine is only a part of the treatment program that should include a healthy diet, regular exercise, and weight reduction as advised by your doctor.
The most common side effects of this medicine include urinary tract infection, nasal congestion, sore throat, and upper respiratory tract infection. Drinking plenty of fluids while using it will help prevent dehydration. Some people may develop fungal infections in the genital area. Maintaining good hygiene can help prevent this.
Before taking Simezan-D Tablet ER, inform your doctor if you have any kidney or liver problems, a urinary tract infection, or if you are on water pills (diuretics). Pregnant or breastfeeding women should also consult their doctor before taking it. Avoid excessive alcohol intake while taking this medicine, as this may increase the risk of some side effects. Monitor your blood sugar levels regularly while taking this medicine.
Uses of Simezan-D Tablet ER
Benefits of Simezan-D Tablet ER
In Treatment of Type 2 diabetes mellitus
Simezan-D Tablet ER is a medicine that helps control high blood glucose (sugar) levels. It helps get rid of extra glucose from the body through urine. Lowering blood glucose levels is an essential part of managing diabetes, as this reduces the risk of serious complications, such as kidney damage, eye damage, nerve problems, and loss of limbs. This medicine will reduce the risk of death from cardiovascular disease if you have type 2 diabetes and cardiovascular disease. Taking Simezan-D Tablet ER regularly with proper diet and exercise will help you live a normal, healthy life. You should keep using it for as long as it is prescribed for a healthy future.
Side effects of Simezan-D Tablet ER
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Simezan-D
- Diarrhea
- Nausea
- Vomiting
- Flatulence
- Genital fungal infection
- Nasopharyngitis (inflammation of the throat and nasal passages)
- Urinary tract infection
- Headache
How to use Simezan-D Tablet ER
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Simezan-D Tablet ER may be taken with or without food, but it is better to take it at a fixed time.
How Simezan-D Tablet ER works
Simezan-D Tablet ER is a combination of three antidiabetic medicines. Dapagliflozin increases urinary glucose excretion and reduces blood glucose levels. Metformin decreases the amount of glucose you absorb from your food and the amount of glucose made by the liver. Metformin also increases the body's response to insulin, a natural substance that controls the amount of glucose in the blood. Sitagliptin helps control blood sugar levels by increasing substances (incretins) in the body that make the pancreas release more insulin. It also signals the liver to stop producing sugar (glucose) when there is too much sugar in the blood.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Simezan-D Tablet ER. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Information regarding the use of Simezan-D Tablet ER during pregnancy is not available. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Simezan-D Tablet ER during breastfeeding is not available. Please consult your doctor.
Driving
UNSAFE
Simezan-D Tablet ER may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Simezan-D Tablet ER should be used with caution in patients with kidney disease. Dose adjustment of Simezan-D Tablet ER may be needed. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Simezan-D Tablet ER in patients with liver disease. Please consult your doctor.
What if you forget to take Simezan-D Tablet ER?
If you miss a dose of Simezan-D Tablet ER, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Simezan-D Tablet ER
₹28.1/Tablet ER
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Quick tips
- Your doctor will monitor your blood sugar levels and kidney function regularly while you are taking this medication.
- Hypoglycemia (low blood sugar level) may occur when Simezan-D Tablet ER is taken along with other antidiabetic medicines, alcohol, or when delaying/skipping a meal. Check your blood sugar levels and have a snack/sugar source for immediate relief.
- If you get unusually thirsty, pass urine more frequently, or feel tired, let your doctor know. These are signs that there is too much sugar in your blood, and your dose may need adjusting.
- Lifestyle changes, like a low-fat and salt diet, exercise, not smoking, and cutting down on the amount of alcohol you normally drink, may help this medicine work better.
Fact Box
Habit Forming
No
Therapeutic Class
ANTI DIABETIC
Patient concerns
FAQs
What is Simezan-D Tablet ER used for?
Simezan-D Tablet ER helps lower blood sugar levels in adults with type 2 diabetes. It combines three drugs that work in different ways to improve blood sugar control and may also help with weight loss and protect the heart and kidneys in some people.
Can anyone with diabetes take Simezan-D Tablet ER?
No. Simezan-D Tablet ER is only for adults with type 2 diabetes. It should not be used in people with type 1 diabetes, or those who have severe kidney problems, metabolic acidosis, or diabetic ketoacidosis (DKA)—a serious condition caused by very high blood sugar.
What are the serious side effects of Simezan-D Tablet ER I need to watch for?
During Simezan-D Tablet ER treatment, contact a doctor if serious side effects appear. These may include signs of lactic acidosis (such as weakness, breathing difficulty, or stomach pain), symptoms of ketoacidosis (like nausea, vomiting, confusion, or fruity breath), painful or persistent genital or urinary infections, signs of pancreatitis (severe stomach pain or nausea), or allergic reactions (rash, swelling, or breathing problems). These effects are rare but require prompt medical attention.
Can Simezan-D Tablet ER affect my kidneys or liver?
Yes, people with kidney or liver problems need to be monitored closely or may need a different medication. Your doctor will do regular blood tests to check your kidney and liver function during Simezan-D Tablet ER treatment.
Can I take Simezan-D Tablet ER if I am pregnant or breastfeeding?
Simezan-D Tablet ER is not recommended during pregnancy or breastfeeding. Some of the ingredients may harm the baby or affect milk production. Let your doctor know if you're planning a pregnancy.
Will Simezan-D Tablet ER make my blood sugar too low?
Simezan-D Tablet ER does not usually cause low blood sugar on its own, but it can happen if you take it with insulin or certain diabetes pills. Always carry something sweet (like glucose tablets or candy) in case of symptoms like shakiness, sweating, or dizziness.
What should I avoid while taking Simezan-D Tablet ER?
During Simezan-D Tablet ER treatment, you should avoid drinking alcohol heavily as it increases the risk of lactic acidosis. Also, be cautious with dehydration and drink enough fluids, especially in hot weather or when you're sick.
Can I take other medicines with Simezan-D Tablet ER?
Some medicines, including diuretics (water pills), blood pressure drugs, and steroids, may interact with Simezan-D Tablet ER. Always tell your doctor or pharmacist about all other medicines or supplements you’re using.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Dapagliflozin [Prescribing Information]. Wilmington, DE: AstraZeneca Pharmaceuticals LP; 2020. [Accessed 14 Aug. 2024] (online) Available from:
- Sitagliptin/metformin HCL [Prescribing Information]. Darmstadt, Germany: Merck Sharp & Dohme Corp.; 2012. [Accessed 14 Aug. 2024] (online) Available from:
- Dapagliflozin+Metformin+Sitagliptin [Prescribing Information]. Telangana, India: MSN Laboratories Private Limited; 2022. [Accessed 30 Mar. 2025] (online) Available from:
Marketer details
Name: Zaney Pharma Private Limited
Address: Head Office- H.no 4-7-18/1/A/7, 1st Floor, Raghavendra nagar, Nacharam, Uppal, Hyderabad, Telangana-500076 Corporate Office- Flat No.B.101, Savyaskyz, Newchandkheda, Zundal Cirle, Ahmedabad, Gujarth- 382421
Country of origin: India
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₹281
Inclusive of all taxes
MRP₹315.94 11% OFF
10.0 tablet er in 1 strip
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DapaSach MS 10/1000/100 Tablet ER
strip of 10 tablet er
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Dapagliflozin (10mg) + Metformin (1000mg) + Sitagliptin (100mg)