Dapagliflozin + Metformin + Sitagliptin

Written By Dr. Sakshi Jain

Reviewed By Dr. Rajeev Sharma

Last updated 25 Nov 2025 | 09:37 AM (UTC)

Dapagliflozin + Metformin + Sitagliptin Uses

Dapagliflozin+Metformin+Sitagliptin is used in the treatment of type 2 diabetes mellitus.

How Dapagliflozin + Metformin + Sitagliptin works

Dapagliflozin + Metformin + Sitagliptin is a combination of three antidiabetic medicines. Dapagliflozin increases urinary glucose excretion and reduces blood glucose levels. Metformin decreases the amount of glucose you absorb from your food and the amount of glucose made by the liver. Metformin also increases the body's response to insulin, a natural substance that controls the amount of glucose in the blood. Sitagliptin helps control blood sugar levels by increasing substances (incretins) in the body that make the pancreas release more insulin. It also signals the liver to stop producing sugar (glucose) when there is too much sugar in the blood.

Common side effects of Dapagliflozin + Metformin + Sitagliptin

Diarrhea, Nausea, Vomiting, Flatulence, Polyuria, Dyslipidemia, Genital fungal infection, Nasopharyngitis (inflammation of the throat and nasal passages), Urinary tract infection, Headache, Hypoglycemia (low blood glucose level), Conjunctivitis, Cough

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Medicine brands for Dapagliflozin + Metformin + Sitagliptin

Dapaflix SM

Bonne Sante Therapeutics India Ltd

₹185 to ₹185

1 variant(s)

Glipwin DM

Healanthra Lifesciences

₹178 to ₹192

2 variant(s)

Zysita Trio

Three Dots Lifescience

₹232 to ₹232

1 variant(s)

Sitaviron DM

Nvron Life Science Ltd

₹206 to ₹206

1 variant(s)

Sitadeg DM

Bioiris Pharmaceuticals Pvt Ltd

₹190 to ₹190

1 variant(s)

T2DSM

Delavie Kawai Life Science Pvt. Ltd.

₹139 to ₹139

1 variant(s)

Zeusit Trio

Opsiscare Lifesciences Pvt Ltd

Cafoli Lifecare Pvt. Ltd.

₹299 to ₹299

1 variant(s)

Daparange-Trio

Neomac Pharmaceuticals Pvt Ltd

₹194 to ₹202

2 variant(s)

Expert advice for Dapagliflozin + Metformin + Sitagliptin

Your doctor will monitor your blood sugar levels and kidney functions regularly while you are taking this medication.
Hypoglycemia (low blood sugar level) may occur when Dapagliflozin + Metformin + Sitagliptin is taken along with other antidiabetic medicines, alcohol, or on delaying/skipping a meal. Check your blood sugar levels and have a snack/sugar source for immediate relief.
If you get unusually thirsty, pass urine more frequently, and feel tired, let your doctor know. These are signs that there is too much sugar in your blood and your dose may need adjusting.
Lifestyle changes, like low-fat and salt diet, exercise, not smoking, and cutting down on the amount of alcohol you normally drink, may help this medicine work better.