






Sematrinity 2mg Pre-filled Pen
Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 12 Sep 2026 | 01:04 AM (IST)
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Products such as this are non-returnable to make sure that the next person doesn’t get a used item
Product expires after Jan, 2028
Expiry date may vary by batch. All batches have a 3-month shelf life from the date of dispatch.
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Product introduction
Sematrinity 2mg Pre-filled Pen is given as an injection under the skin, usually once a week. Use it on the same day every week, preferably at the same time, to help maintain consistent blood sugar control. Follow your doctor's instructions carefully and do not change your dose without medical advice.
The most common side effects of Sematrinity 2mg Pre-filled Pen include nausea, vomiting, diarrhea, constipation, stomach pain, indigestion, and reduced appetite. These side effects are usually mild and tend to improve as your body gets used to the medicine. Eating smaller meals, avoiding greasy or spicy foods, and drinking plenty of fluids may help reduce stomach-related side effects. If any of these symptoms persist or get worse, contact your doctor.
Before using Sematrinity 2mg Pre-filled Pen, tell your doctor if you have or have ever had pancreatitis, diabetic eye disease (diabetic retinopathy), kidney problems, or any severe stomach or intestinal disorders. Do not use this medicine if you are allergic to semaglutide or any of its ingredients. This medicine is not intended for the treatment of type 1 diabetes and is not a substitute for insulin.
Tell your doctor about all the medicines, vitamins, and herbal supplements you are taking, as some medicines, especially insulin or sulfonylureas, may increase the risk of low blood sugar when used together with Sematrinity 2mg Pre-filled Pen. Avoid excessive alcohol consumption as it may affect your blood sugar levels. This medicine is not recommended during pregnancy, and women planning pregnancy should stop treatment at least 2 months before becoming pregnant. It is also not recommended while breastfeeding unless advised by your doctor.
Uses of Sematrinity Solution for Injection
Benefits of Sematrinity Solution for Injection
Sematrinity 2mg Pre-filled Pen helps adults with type 2 diabetes improve blood sugar control when used along with a healthy diet and regular exercise. It works by increasing insulin release when blood sugar levels are high, reducing the amount of sugar produced by the liver, and slowing the movement of food from the stomach. This helps lower both fasting and after-meal blood sugar levels. It may also help reduce appetite and support weight loss in some people. Better blood sugar control over time may help lower the risk of diabetes-related complications.
Side effects of Sematrinity Solution for Injection
- Nausea
- Vomiting
- Diarrhea
- Constipation
How to use Sematrinity Solution for Injection
How Sematrinity Solution for Injection works
Quick tips
- Administer Sematrinity 2mg Pre-filled Pen on the same day each week. Set a reminder to help you remember.
- To prevent skin irritation or lumps, administer the medication to different areas of the abdomen, thigh, or upper arm.
- Check your blood sugar levels regularly to prevent hypoglycemia (low blood sugar) and address any unexpected symptoms.
- Eat small, frequent, balanced meals, and avoid greasy, high-fat foods to reduce nausea.
- Drink plenty of water to counteract potential dehydration from nausea, vomiting, or diarrhea.
- Be watchful of symptoms like severe stomach pain, signs of pancreatitis (such as severe upper abdominal pain that may radiate to the back, along with nausea, vomiting, or fever), or allergic reactions, and consult a doctor immediately if they occur.
- Let doctors know you are taking Sematrinity 2mg Pre-filled Pen before surgeries, as it may delay stomach emptying and increase aspiration risk.
Safety advice

Alcohol

Pregnancy

Breast feeding

Driving
However, some people may experience dizziness during dose escalation. Do not drive if you experience dizziness.

Kidney
However, this medicine is not recommended in patients with severe renal impairment or end-stage renal disease due to limited clinical experience.

Liver
It is not recommended for patients with severe hepatic impairment.

Frequently asked questions
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References
- Semaglutide [Prescribing Information]. Plainsboro, NJ: Novo Nordisk Inc.; 2025. [Accessed 11 Dec. 2025] (online) Available from:
- Semaglutide [Prescribing Information]. Bagsvaerd, Denmark: Novo Nordisk A/S; 2025. [Accessed 11 Dec. 2025 (online). Available from:
- European Medicines Agency: EPAR summary for the public. Semaglutide; 2018. [Accessed 03/12/2024] (online) Available from:




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Disclaimer
Marketer details
Address: Haloi-Baroda Highway, Halol-389350, Dist. Panchmahal, Gujarat
Vendor Details
A licensed vendor partner from your nearest location will deliver Sematrinity 2mg Pre-filled Pen. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- PPBS (Postprandial Blood Sugar)
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid -19 test- RT PCR
- LFT (Liver Function Test)
- KFT (Kidney Function Test)
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid, Serum
- Vitamin B12
- CRP (C-Reactive Protein), Quantitative
- Urine C/S (Urine Culture and Sensitivity)
- Serum Electrolytes
- Serum Calcium
- Serum Creatinine
- Diabetes Screening (HbA1C & Fasting Sugar)
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hb (Hemoglobin)
- Complete Hemogram (CBC & ESR)














