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Sematrinity 2mg Pre-filled Pen 1
Sematrinity 2mg Pre-filled Pen 2
Sematrinity 2mg Pre-filled Pen 3
Sematrinity 2mg Pre-filled Pen 4
Sematrinity 2mg Pre-filled Pen 5
Sematrinity 2mg Pre-filled Pen 6
Sematrinity 2mg Pre-filled Pen 7

Sematrinity 2mg Pre-filled Pen

Semaglutide (1.34mg/ml)
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Cold stored
Stored between 2-8°C
Sematrinity 2mg Pre-filled Pen is an antidiabetic medicine (GLP-1 receptor agonist) used to improve blood sugar control in adults with type 2 diabetes. It helps lower blood sugar by increasing insulin release when blood sugar levels are high, reducing the amount of sugar made by the liver, and slowing digestion.

Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 12 Sep 2026 | 01:04 AM (IST)
₹885
/ month (3 months)
with EMI on select credit cards
All EMI Plans
Price without EMI
₹2605
MRP ₹2960
12% off
(Inclusive of applicable taxes)
1.5 ml Solution for Injection
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Products such as this are non-returnable to make sure that the next person doesn’t get a used item

Product expires after Jan, 2028

Expiry date may vary by batch. All batches have a 3-month shelf life from the date of dispatch.

Price Info

MRP may vary by batch. Any additional charges, including packaging, handling, shipping or delivery charges, will be clearly disclosed before purchase.

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10% cashback up to 200 on Min Transaction of Rs.1000, for first time users of Airtel Payments Bank.
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General Information

Contains

Semaglutide (1.34mg/ml)

Marketer

Sun Pharmaceutical Industries Ltd

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.
The content is shown in English
Sematrinity 2mg Pre-filled Pen 1
Sematrinity 2mg Pre-filled Pen 2
Sematrinity 2mg Pre-filled Pen 3
Sematrinity 2mg Pre-filled Pen 4
Sematrinity 2mg Pre-filled Pen 5
Sematrinity 2mg Pre-filled Pen 6
Sematrinity 2mg Pre-filled Pen 7

Product introduction

Sematrinity 2mg Pre-filled Pen is given as an injection under the skin, usually once a week. Use it on the same day every week, preferably at the same time, to help maintain consistent blood sugar control. Follow your doctor's instructions carefully and do not change your dose without medical advice.


The most common side effects of Sematrinity 2mg Pre-filled Pen include nausea, vomiting, diarrhea, constipation, stomach pain, indigestion, and reduced appetite. These side effects are usually mild and tend to improve as your body gets used to the medicine. Eating smaller meals, avoiding greasy or spicy foods, and drinking plenty of fluids may help reduce stomach-related side effects. If any of these symptoms persist or get worse, contact your doctor.


Before using Sematrinity 2mg Pre-filled Pen, tell your doctor if you have or have ever had pancreatitis, diabetic eye disease (diabetic retinopathy), kidney problems, or any severe stomach or intestinal disorders. Do not use this medicine if you are allergic to semaglutide or any of its ingredients. This medicine is not intended for the treatment of type 1 diabetes and is not a substitute for insulin.


Tell your doctor about all the medicines, vitamins, and herbal supplements you are taking, as some medicines, especially insulin or sulfonylureas, may increase the risk of low blood sugar when used together with Sematrinity 2mg Pre-filled Pen. Avoid excessive alcohol consumption as it may affect your blood sugar levels. This medicine is not recommended during pregnancy, and women planning pregnancy should stop treatment at least 2 months before becoming pregnant. It is also not recommended while breastfeeding unless advised by your doctor.

Uses of Sematrinity Solution for Injection

Benefits of Sematrinity Solution for Injection

Treatment of Type 2 diabetes mellitus
Sematrinity 2mg Pre-filled Pen helps adults with type 2 diabetes improve blood sugar control when used along with a healthy diet and regular exercise. It works by increasing insulin release when blood sugar levels are high, reducing the amount of sugar produced by the liver, and slowing the movement of food from the stomach. This helps lower both fasting and after-meal blood sugar levels. It may also help reduce appetite and support weight loss in some people. Better blood sugar control over time may help lower the risk of diabetes-related complications.

Side effects of Sematrinity Solution for Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Sematrinity
  • Nausea
  • Vomiting
  • Diarrhea
  • Constipation

How to use Sematrinity Solution for Injection

Your doctor or nurse will guide you how to use this medicine.

How Sematrinity Solution for Injection works

Sematrinity 2mg Pre-filled Pen is a GLP-1 receptor agonist that works like the natural GLP-1 hormone in the body. It increases insulin release when blood sugar levels are high, reduces glucagon release, slows stomach emptying, and decreases the amount of sugar produced by the liver. These actions help improve blood sugar control in adults with type 2 diabetes.

Quick tips

  • Administer Sematrinity 2mg Pre-filled Pen on the same day each week. Set a reminder to help you remember.
  • To prevent skin irritation or lumps, administer the medication to different areas of the abdomen, thigh, or upper arm.
  • Check your blood sugar levels regularly to prevent hypoglycemia (low blood sugar) and address any unexpected symptoms.
  • Eat small, frequent, balanced meals, and avoid greasy, high-fat foods to reduce nausea.
  • Drink plenty of water to counteract potential dehydration from nausea, vomiting, or diarrhea.
  • Be watchful of symptoms like severe stomach pain, signs of pancreatitis (such as severe upper abdominal pain that may radiate to the back, along with nausea, vomiting, or fever), or allergic reactions, and consult a doctor immediately if they occur.
  • Let doctors know you are taking Sematrinity 2mg Pre-filled Pen before surgeries, as it may delay stomach emptying and increase aspiration risk.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Sematrinity 2mg Pre-filled Pen. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Sematrinity 2mg Pre-filled Pen is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

UNSAFE
Sematrinity 2mg Pre-filled Pen is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving

Driving

CAUTION
Sematrinity 2mg Pre-filled Pen may affect your driving ability if your blood sugar becomes too low or too high. Monitor your blood glucose and avoid driving if affected.
However, some people may experience dizziness during dose escalation. Do not drive if you experience dizziness.
Kidney

Kidney

SAFE IF PRESCRIBED
Sematrinity 2mg Pre-filled Pen is safe to use in patients with kidney disease. No dose adjustment is recommended.
However, this medicine is not recommended in patients with severe renal impairment or end-stage renal disease due to limited clinical experience.
Liver

Liver

CAUTION
Sematrinity 2mg Pre-filled Pen should be used with caution in patients with liver disease. Dose adjustment may be needed.
It is not recommended for patients with severe hepatic impairment.
All

Frequently asked questions

Sematrinity 2mg Pre-filled Pen is administered once a week as an injection under the skin. Your doctor will guide you on how to use it properly and where to inject it.
While Sematrinity 2mg Pre-filled Pen alone is unlikely to cause low blood sugar, the risk may increase if it is used alongside other diabetes medicines, such as insulin or sulfonylureas. To minimize this risk, monitor your blood sugar levels regularly and follow your doctor’s guidance on dosing.
In rare cases, Sematrinity 2mg Pre-filled Pen can increase the risk of pancreatitis, thyroid tumors, or low blood sugar (especially if taken with other diabetes medications). Let your doctor know if you have a personal or family history of thyroid cancer or severe stomach issues.
Avoid excessive consumption of alcohol, as it can affect your blood sugar levels and increase side effects. Stay hydrated, especially if you experience nausea or diarrhea. Additionally, inform your doctor about any medical conditions or medicines you are taking to avoid potential interactions.
Keep this medicine out of the sight and reach of children. Store Sematrinity 2mg Pre-filled Pen in a refrigerator (2°C to 8°C) until ready for use. Do not freeze, and do not use the medicine if it has been frozen. Protect it from direct sunlight. After first use, store the pen below 30°C or in a refrigerator (2°C to 8°C). Keep the pen cap on when not in use to protect it from light. Always remove the injection needle after each injection and store the pen without a needle attached.
While it helps control blood sugar, it has been linked to a risk of loss of vision in diabetic individuals already experiencing visual disturbances. If you experience any changes in vision while using Sematrinity 2mg Pre-filled Pen, consult your doctor for guidance and monitoring.

Fact Box

Chemical Class

Polypeptides

Habit Forming

No

Therapeutic Class

OTHERS

Action Class

Glucagon-Like Peptide-1 (GLP-1) Receptor Agonists
100% genuine products
100% genuine products
Safe & secure payments
Safe & secure payments
No contact delivery
No contact delivery
Fully sanitized facilities
Fully sanitized facilities
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Sun Pharmaceutical Industries Ltd
Address: Haloi-Baroda Highway, Halol-389350, Dist. Panchmahal, Gujarat

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Sematrinity 2mg Pre-filled Pen. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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