Roglimet 2mg/500mg/2mg Tablet

Glimepiride (2mg)+ Metformin (500mg)+ Rosiglitazone (2mg)

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Roglimet 2mg/500mg/2mg Tablet is a combination medicine that helps control blood sugar levels. This medicine is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. It helps in proper utilisation of insulin, thereby lowering the blood sugar levels.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 27 Jul 2026 | 01:03 AM (IST)

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General Information

Contains

Glimepiride (2mg)+ Metformin (500mg)+ Rosiglitazone (2mg)

Marketer

Wockhardt Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Roglimet 2mg/500mg/2mg Tablet should be taken in the dose and duration as advised by your doctor. It must be taken with food to avoid stomach upset. If you miss a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose. Overdose may lead to low blood sugar (hypoglycemia).

Some people may develop hypoglycemia (low blood sugar level) when this medicine is taken along with other antidiabetic medicines, alcohol or upon skipping a meal. Monitor your blood sugar levels regularly while taking it. Other common side effects of this medicine include nausea, taste changes, diarrhea, stomach pain, headache, edema (swelling), blurred vision, bone fracture, and respiratory tract infection.

Before taking this medicine, inform your doctor if you have any kidney, liver or heart problems. Pregnant or breastfeeding women should also consult their doctor before taking it. Your doctor will check your kidney function tests before starting treatment with it. Avoid excessive alcohol intake while taking it as this may increase the risk of developing some side effects.

Uses of Roglimet Tablet

Treatment of Type 2 diabetes mellitus

Benefits of Roglimet Tablet

Treatment of Type 2 diabetes mellitus
Type 2 diabetes mellitus is a long-term condition where the body either does not produce enough insulin or becomes resistant to its effects, causing high blood sugar levels. Over time, this can lead to complications like heart disease, kidney problems, nerve damage, and vision issues. Roglimet 2mg/500mg/2mg Tablet helps lower and stabilize blood sugar levels by improving insulin action and controlling glucose production in the body. Maintaining better blood sugar control with this combination reduces the risk of diabetes-related complications and supports overall health.

Side effects of Roglimet Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Roglimet

Hypoglycemia (low blood glucose level)
Nausea
Taste change
Diarrhea
Stomach pain
Headache
Edema (swelling)
Weight gain
Blurred vision
Bone fracture
Respiratory tract infection

How to use Roglimet Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Roglimet 2mg/500mg/2mg Tablet should be taken with or after food.

How Roglimet Tablet works

Roglimet 2mg/500mg/2mg Tablet is a combination of three antidiabetic medicines: Glimepiride, Metformin and Rosiglitazone. They work by different mechanisms to provide better control of blood sugar when single or dual therapy is not effective. Glimepiride is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide. It works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin. Rosiglitazone is a thiazolidinedione which further increases insulin sensitivity.

Quick tips

Take it with food to lower your chance of having an upset stomach.
It may cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
Always carry some sugary food or fruit juice with you in case you experience hypoglycemic symptoms such as cold sweats, cool pale skin, tremor, and anxiety.
Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).
Take it with food to lower your chance of having an upset stomach.
It may cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
Always carry some sugary food or fruit juice with you in case you experience hypoglycemic symptoms such as cold sweats, cool pale skin, tremor, and anxiety.
Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Roglimet 2mg/500mg/2mg Tablet

Pregnancy

CONSULT YOUR DOCTOR

Roglimet 2mg/500mg/2mg Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CONSULT YOUR DOCTOR

Roglimet 2mg/500mg/2mg Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

UNSAFE

Roglimet 2mg/500mg/2mg Tablet may cause side effects that could affect your ability to drive.

Kidney

CAUTION

Roglimet 2mg/500mg/2mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Use of Roglimet 2mg/500mg/2mg Tablet is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.

Liver

UNSAFE

Roglimet 2mg/500mg/2mg Tablet is unsafe to use in patients with liver disease and should be avoided.
Inform your doctor if you develop any signs and symptoms of jaundice while taking this medicine.

Fact Box

Habit Forming

Therapeutic Class

ANTI DIABETIC

Related lab tests

Glucose - Fasting Blood

Glucose - Postprandial Blood

Glycosylated Hemoglobin

References

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Wockhardt Ltd
Address: Wockhardt Towers, Bandra Kurla Complex, Bandra (East), Mumbai 400051, Maharashtra, India

Vendor Details

Country of origin: India

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Roglimet 2mg/500mg/2mg Tablet

Roglimet 2mg/500mg/2mg Tablet

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Roglimet Tablet

Benefits of Roglimet Tablet

Side effects of Roglimet Tablet

How to use Roglimet Tablet

How Roglimet Tablet works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Fact Box

Habit Forming

Therapeutic Class

Related lab tests

Glucose - Fasting Blood

Glucose - Postprandial Blood

Glycosylated Hemoglobin

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests