Rifaxant-Plus Tablet

Rifaximin (200mg)+ Metronidazole (400mg)

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Prescription

required

Rifaxant-Plus Tablet is a combination medicine that is used to treat infectious diarrhea. It prevents the growth of microorganisms to treat the infection.

Written By Dr. Syeda Aafia, MBA, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 25 Nov 2025 | 03:07 PM (IST)

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As per Ministry of Health and Family Welfare

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General Information

Contains

Rifaximin (200mg)+ Metronidazole (400mg)

Marketer

Ernst Pharmacia

Storage

Store below 25°C

The content is shown in English

Product introduction

Rifaxant-Plus Tablet is a prescription medicine that is advised to be taken as suggested by the doctor. It should be taken with or without food and it must be taken at a fixed time to ensure better efficacy. Do not consume more than the recommended dose, as an overdose of it may have harmful effects on your body. If you miss a dose, take it as soon as you remember. The treatment must be completed even if you feel better to ensure a complete recovery.

Rifaxant-Plus Tablet may lead to some side effects such as nausea, vomiting, stomach pain, loss of appetite, headache, etc. To overcome any such side effects, it is advised to eat a healthy balanced diet and drink plenty of fluid. If any of the side effects get aggravated, contact your doctor immediately. If you experience any allergic reaction (rashes, itching, swelling, shortness of breath, etc.), you must consult your doctor immediately.

Before taking this medicine, you should tell your doctor if you have any problems with your liver or kidneys. Also, tell your doctor if you are on any medication for any health condition. Pregnant or breastfeeding women should also consult with the doctors before taking it. Avoid drinking alcohol as it can cause excessive dizziness with this medicine. It usually does not impair your ability to drive, but you should not drive if it makes you feel sleepy or dizzy. If you are a known allergic to the medicine, you must refrain from using this medicine and consult your doctor. It is advised to take proper rest during the course of treatment for the medicine to work effectively.

Uses of Rifaxant-Plus Tablet

Treatment of Infectious diarrhea

Benefits of Rifaxant-Plus Tablet

Treatment of Infectious diarrhea
Diarrhea is a condition in which you frequently pass loose, watery stools. Rifaxant-Plus Tablet reduces the frequency of loose motions and also helps you to stay well by preventing them from coming back. It works by killing the microorganisms causing infections as well as prevents them from multiplying. Since diarrhea causes loss of fluid from the body, drink plenty of fluids to make sure you stay hydrated.

Side effects of Rifaxant-Plus Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Rifaxant-Plus

Nausea
Vomiting
Diarrhea
Stomach pain
Constipation
Dryness in mouth
Flatulence
Fever
Headache
Metallic taste
Dizziness
Abdominal distension
Tenesmus (increased urge to pass stools)
Bowel incontinence

How to use Rifaxant-Plus Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Rifaxant-Plus Tablet may be taken with or without food.

How Rifaxant-Plus Tablet works

Rifaxant-Plus Tablet is a combination of two antibiotics: Rifaximin and Metronidazole which treat infectious diarrhoea. These antibiotics work in the digestive tract by killing the bacteria and other microorganisms that cause diarrhoea. This treats your infection and relieves symptoms.

Quick tips

You have been prescribed Rifaxant-Plus Tablet for the treatment of infectious diarrhea.
Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection come back and harder to treat.
It is advisable to drink plenty of fluids and a healthy diet while taking the medicine.
It may cause dizziness. Do not drive or do anything that requires mental focus until you know how the medicine affects you.
Avoid consuming alcohol while taking medication as it may cause increased side effects.
Discontinue Rifaxant-Plus Tablet and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing.

Safety advice

Alcohol

UNSAFE

Consumption of alcohol with Rifaxant-Plus Tablet may cause a disulfiram-like reaction, leading to symptoms such as flushing, increased heart rate, low blood pressure, nausea, lightheadedness, and severe headache.

Pregnancy

CONSULT YOUR DOCTOR

The safety of Rifaxant-Plus Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

SAFE IF PRESCRIBED

Rifaxant-Plus Tablet may be safe to use during breastfeeding. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Driving

UNSAFE

Rifaxant-Plus Tablet may cause side effects that could affect your ability to drive.
Rifaxant-Plus Tablet may make you feel sleepy, dizzy, confused. You may have hallucinations, fits (convulsions) or temporary eyesight problems (such as blurred or double vision) affecting your ability to drive.

Kidney

SAFE IF PRESCRIBED

Rifaxant-Plus Tablet is probably safe to use in patients with kidney disease. Limited data suggest dose adjustment may not be needed.

Liver

CAUTION

Rifaxant-Plus Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.

Frequently asked questions

Can the use of Rifaxant-Plus Tablet cause metallic taste?

Yes, the use of Rifaxant-Plus Tablet can cause a temporary metallic taste. This metallic taste can be reduced by chewing sugar-free gum or mints and brushing teeth after your meals.

Can the use of Rifaxant-Plus Tablet cause dryness in the mouth?

Yes, the use of Rifaxant-Plus Tablet can cause dry mouth. If you experience dry mouth, drink plenty of water, Take regular sips during the day and keep some water by your bed at night. You may use lip balm if your lips are also dry.

Can I take a higher dose of this medicine than recommended?

No, taking higher than the recommended dose of Rifaxant-Plus Tablet can lead to increased side effects. If you are experiencing increased severity of your symptoms, please consult your doctor for re-evaluation.

What are the contraindications of Rifaxant-Plus Tablet?

The use of Rifaxant-Plus Tablet should be avoided in patients with known allergy to any of the component or excipients of this medicine and tell your doctor if you have or had liver disease.

What should I know about storage and disposal of Rifaxant-Plus Tablet?

Keep this medicine in the container or pack it came in, tightly closed. Store it as mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children, and other people.

Fact Box

Habit Forming

Therapeutic Class

GASTRO INTESTINAL

Related lab tests

Culture Stool

Stool Examination R/M

References

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Ernst Pharmacia
Address: 175, Ground Floor, Industrial Area, Phase 1, Panchkula, Haryana - 134113, India

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?