Retune-LS Tablet

Levosulpiride (25mg)

Genuine

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Prescription

required

Retune-LS Tablet is used in the treatment of gastric problems like nausea, vomiting, heartburn, or indigestion. It also prevents acid reflux (acid going up to the food pipe) and hence helps in the treatment of gastroesophageal reflux disease (GERD).

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 23 Jan 2026 | 05:35 PM (IST)

₹35.7 MRP ₹39.5610% off

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General Information

Contains

Levosulpiride (25mg)

Marketer

Zuventus Healthcare Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Retune-LS Tablet is taken by mouth with or without food. However, it is advisable to take it at the same time each day as this helps to maintain consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember.

Some common side effects of this medicine includes headache and fatigue. It also causes dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. You should immediately consult doctor if you have absence of periods, abnormal milk secretion, changes in sexual desire, or fever after taking this medicine.

Uses of Retune-LS Tablet

Benefits of Retune-LS Tablet

Heartburn
Heartburn is caused by stomach acid irritating the food pipe, leading to a burning sensation in the chest. Retune-LS Tablet helps improve stomach emptying and reduces acid-related discomfort, which helps relieve burning sensations and improves eating comfort.

Irritable bowel syndrome
Irritable bowel syndrome is a digestive condition that causes abdominal pain, bloating, and irregular bowel movements. Retune-LS Tablet helps improve gut movement and reduces discomfort, which can ease bloating, pain, and bowel irregularity, supporting better digestive comfort.

Gastroesophageal reflux disease (Acid reflux)
Acid reflux occurs when stomach contents flow back into the food pipe, causing irritation and discomfort. Retune-LS Tablet helps reduce reflux episodes by supporting proper stomach movement, which lowers acid backflow and improves long-term symptom control and quality of life.

Side effects of Retune-LS Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Retune-LS

Increased prolactin level in blood
Insomnia (difficulty in sleeping)
Sedation
Maculopapular rash
Extrapyramidal symptoms
Akathisia (inability to stay still)
Increased liver enzymes
Constipation
Weight gain

How to use Retune-LS Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Retune-LS Tablet may be taken with or without food.

How Retune-LS Tablet works

Retune-LS Tablet is a atypical antipsychotic. It works by increasing the release of acetylcholine (a chemical messenger). This increases the movement of stomach and intestines, and prevents reflux (acid going up to the food pipe).

All substitutes for Retune-LS Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Take it as per dose and duration suggested by your doctor.
Retune-LS Tablet may cause dizziness. Do not drive or do anything that requires mental focus until you know how this medicine affects you.
Consult your doctor if you are pregnant, planning to become pregnant or breastfeeding.
Consult with your doctor immediately if you have absence if periods, abnormal milk secretion or changes in sexual desire, fever, muscle stiffness.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Retune-LS Tablet

Pregnancy

CONSULT YOUR DOCTOR

Retune-LS Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Retune-LS Tablet during breastfeeding is not available. Please consult your doctor.

Driving

UNSAFE

Retune-LS Tablet may cause side effects that could affect your ability to drive.
Retune-LS Tablet may cause drowsiness, numbness, or dyskinesias, therefore they should be advised to avoid driving and operations requiring supervision.

Kidney

CAUTION

Retune-LS Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

CAUTION

Retune-LS Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Retune-LS with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Moderate

Metoclopramide (Oral Route)

Talk to your doctor if you notice any unusual symptoms.

Moderate

Metoclopramide (Injection Route)

Talk to your doctor if you notice any unusual symptoms.

Frequently asked questions

What is Retune-LS Tablet used for?

Retune-LS Tablet is mainly used to treat gastric problems like nausea, vomiting, heartburn, or indigestion. This medicine may be used sometimes to manage mental health conditions like depression or schizophrenia, depending on the dose.

What are the serious side effects of Retune-LS Tablet?

Although rare, serious side effects of Retune-LS Tablet may include muscle stiffness or shaking, high fever (possible neuroleptic malignant syndrome), seizures, and abnormal heart rhythm. You should seek immediate help if you notice any of these symptoms.

Who should not take Retune-LS Tablet?

Individuals should not take Retune-LS Tablet if they are allergic to any ingredient present in Retune-LS Tablet, have epilepsy or seizures, have breast cancer or tumors dependent on prolactin, or have severe kidney or liver disease.

Can I drive while taking Retune-LS Tablet?

You should avoid driving or using heavy machines if you feel drowsy, dizzy, or restless after taking Retune-LS Tablet, especially during the first few days.

What precautions should I take while using Retune-LS Tablet?

While using Retune-LS Tablet, you should avoid alcohol, monitor for abnormal movements or hormone changes, take medicine at the same time daily, and do not stop suddenly without medical advice.

Can Retune-LS Tablet affect my hormones?

Yes. Retune-LS Tablet may raise prolactin levels, which can cause symptoms like missed periods, milk discharge, or enlarged breasts in both men and women.

Is levosulpiride safe?

Levosulpiride is safe if used at prescribed doses for the prescribed duration as advised by your doctor

Is levosulpiride an antidepressant?

No, it is used in the treatment of gastro-oesophageal reflux disease, irritable bowel syndrome, psychosis, dyspepsia

What is levosulpiride?

Levosulpiride belong to class of medication called as atypical antipsychotics. It acts by decreasing the activity of dopamine in the brain

What are its uses?

Levosulpiride is used in the treatment psychosis, depression, gastro-oesophageal reflux disease, irritable bowel syndrome and dyspepsia

Does levosulpiride cause erectile dysfunction?

No. patients should follow advice of the doctor regarding the possible side effects.

Can I take Retune-LS Tablet with omeprazole?

Retune-LS Tablet can be safely taken with omeprazole as no harmful effects have been reported clinically. A fixed-dose combination of these two medicines is also available. Retune-LS Tablet works by increasing the gut motility and Omeprazole decreases the acid production in the stomach. So, this combination is very effective in the treatment of reflux esophagitis associated with acidity, heartburn, intestinal and stomach ulcers.

Fact Box

Chemical Class

Benzamide derivative

Habit Forming

Therapeutic Class

NEURO CNS

Action Class

Atypical Antipsychotics

Related lab tests

Complete Blood Count

References

Lozano R, Concha MP, Montealegre A, et al. Effectiveness and safety of levosulpiride in the treatment of dysmotility-like functional dyspepsia. Ther Clin Risk Manag. 2007;3(1):149-55. [Accessed 23 Jan. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 25 Mar. 2019] (online) Available from:
Levosulpiride [Patient Information Leaflet]. Bangalore, India: Micro Labs Limited; 2022.

User feedback

Patients taking Retune-LS Tablet

Once A Day

54%

Twice A Day

42%

Thrice A Day

What are you using Retune-LS Tablet for?

Heartburn

75%

Vomiting

25%

How much was the improvement?

Average

33%

Poor

33%

Excellent

33%

What were the side-effects while using Retune-LS Tablet?

No Side Effect

100%

How do you take Retune-LS Tablet?

With or without food

50%

Empty stomach

50%

Please rate Retune-LS Tablet on price

Not Expensive

50%

Expensive

50%

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Zuventus Healthcare Ltd
Address: Office No. 5119, 5th Floor, 'D' Wing, Oberoi Garden Estates, Chandivili, Andheri (E), Mumbai - 400 072.

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Retune-LS Tablet

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Retune-LS Tablet

Benefits of Retune-LS Tablet

Side effects of Retune-LS Tablet

How to use Retune-LS Tablet

How Retune-LS Tablet works

All substitutes for Retune-LS Tablet

Lepivil 25mg Tablet

Levogastrol Tablet

Lesuride Tablet

Levazeo 25 Tablet

Neopride Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Metoclopramide (Oral Route)

Metoclopramide (Injection Route)

Frequently asked questions

What is Retune-LS Tablet used for?

What are the serious side effects of Retune-LS Tablet?

Who should not take Retune-LS Tablet?

Can I drive while taking Retune-LS Tablet?

What precautions should I take while using Retune-LS Tablet?

Can Retune-LS Tablet affect my hormones?

Is levosulpiride safe?

Is levosulpiride an antidepressant?

What is levosulpiride?

What are its uses?

Does levosulpiride cause erectile dysfunction?

Can I take Retune-LS Tablet with omeprazole?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Complete Blood Count

References

User feedback

Patients taking Retune-LS Tablet

What are you using Retune-LS Tablet for?

How much was the improvement?

What were the side-effects while using Retune-LS Tablet?

How do you take Retune-LS Tablet?

Please rate Retune-LS Tablet on price

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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