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Razo IV Injection

Rabeprazole (20mg)
Genuine
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Razo IV Injection is a medicine that reduces the amount of acid produced in your stomach. It is used for treating acid-related diseases of the stomach and intestine such as acid reflux, indigestion, peptic ulcer disease, and some other stomach conditions associated with excessive acid production.

Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 09 Mar 2026 | 10:46 AM (IST)
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General Information

The content is shown in English
Razo IV Injection image
Razo IV Injection image
Razo IV Injection image
Razo IV Injection image

Product introduction

Razo IV Injection is fast-acting and provides quick relief from acidity-related problems. It is also used to prevent stress ulcers in seriously ill patients and is administered before anesthetic medication to help prevent aspiration-related complications. It belongs to a class of medicines known as proton pump inhibitors (PPIs).

This medicine is administered into a vein by a healthcare professional and will only be given to you if your doctor thinks that an injection is more suitable for you at the moment than a tablet. The dose will depend on your underlying condition and how you respond to the medicine. Your doctor will decide the duration of treatment but you should keep on taking it as prescribed, even if your symptoms disappear quickly. You can increase the efficiency of the treatment by eating smaller meals more often and avoiding caffeinated drinks (like tea and coffee), and spicy or fatty foods.

The most common side effects observed with this medicine include nausea, vomiting, headache, dizziness, flatulence, diarrhea, stomach pain, and thrombophlebitis (pain, redness, and swelling of the vein). These symptoms are generally mild but if they bother you or do not go away, consult your doctor. Long-term use of this medicine may lead to an increased risk of side effects. For instance, using this medicine for more than 1 year may increase your risk for bone fractures, especially with higher doses. Talk to your doctor about ways to prevent bone loss (osteoporosis), like taking calcium and vitamin D supplements.

Low blood magnesium levels (hypomagnesemia) have been observed in some people taking this medicine for 3 months or more. These reduced levels of magnesium may lead to tiredness, confusion, dizziness, muscle twitches, and an irregular heartbeat. Your doctor may monitor your magnesium levels to prevent this.

Razo IV Injection is not suitable for some people. Before taking this medicine, you need to tell your doctor if you have severe liver problems, are taking medicines for HIV, have ever had an allergic reaction to similar medicines in the past, or suffer from bone loss (osteoporosis). Pregnant or breastfeeding women should also consult their doctor before taking it. Avoid drinking alcohol as it makes your stomach produce excessive acid and can worsen your symptoms. Do not drive or use machinery or tools, if this medicine makes you feel dizzy or sleepy.

Uses of Razo Injection

Benefits of Razo Injection

Acidity
Razo IV Injection is used to relieve acidity by reducing excess stomach acid. It helps ease symptoms like heartburn, indigestion, and stomach discomfort, and supports healing of acid-related conditions such as ulcers.
Gastroesophageal reflux disease (Acid reflux)
GERD is a chronic (long-term) condition which is like having heartburn consistently rather than just occasionally. It happens because a muscle above your stomach relaxes too much and allows stomach contents to come back up into your oesophagus and mouth. Razo IV Injection belongs to a group of medicines called proton pump inhibitors. It reduces the amount of acid your stomach makes and relieves the pain associated with heartburn and acid reflux. You should take it exactly as it is prescribed for it to be effective.
Some simple lifestyle changes can help reduce the symptoms of GERD. Think about what foods trigger heartburn and try to avoid them; eat smaller more frequent meals; try to lose weight if you are overweight and try to find ways to relax. Do not eat within 3-4 hours of going to bed.
Peptic ulcer disease
Razo IV Injection belongs to a group of medicines called proton pump inhibitors. It reduces the amount of acid your stomach makes which prevents further damage to the ulcer as it heals naturally. You may be given other medicines along with this medicine depending on what caused the ulcer. It is given as an injection by your doctor or healthcare provider.

Side effects of Razo Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Razo
  • Abdominal pain
  • Weakness
  • Diarrhea
  • Thrombophlebitis
  • Headache
  • Nausea
  • Vomiting
  • Flatulence
  • Dizziness

How to use Razo Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Razo Injection works

Razo IV Injection is a proton pump inhibitor (PPI). It works by reducing the amount of acid in the stomach which helps in relief of acid related indigestion and heartburn.

Quick tips

  • Your doctor will administer Razo IV Injection as an injection into a vein.
  • It is a well-tolerated medicine and provides relief for a long time.
  • Some healthy tips to prevent acidity from happening:
    • Avoid excessive intake of carbonated beverages/soft drinks, citrus juices, fried food, caffeinated beverages like tea and coffee.
    • Avoid alcohol and smoking.
    • Avoid eating late at night or before bedtime.
  • Inform your doctor if you get watery diarrhea, fever or stomach pain that does not go away.
  • Long-term use of Razo IV Injection can cause weak bones and a deficiency of minerals such as magnesium. Take adequate dietary intake of calcium and magnesium or their supplements as prescribed by your doctor.
  • Consult your doctor right away if you develop decreased urination, edema (swelling due to fluid retention), lower back pain, nausea, fatigue, and rash or fever. These could be signs of a kidney problem.
  • Razo IV Injection should be taken 1 hour before a meal, preferably in the morning.
  • It is a well-tolerated medicine and provides relief for a long time.
  • Some healthy tips to prevent acidity from happening:
    • Avoid excessive intake of carbonated beverages/soft drinks, citrus juices, fried food, caffeinated beverages like tea and coffee.
    • Avoid alcohol and smoking.
    • Avoid eating late at night or before bedtime.
  • Inform your doctor if you get watery diarrhea, fever or stomach pain that does not go away.
  • Inform your doctor if you do not feel better after taking it for 14 days as you may be suffering from some other problem that needs attention.
  • Long-term use of Razo IV Injection can cause weak bones and a deficiency of minerals such as magnesium. Take adequate dietary intake of calcium and magnesium or their supplements as prescribed by your doctor.
  • Consult your doctor right away if you develop decreased urination, edema (swelling due to fluid retention), lower back pain, nausea, fatigue, and rash or fever. These could be signs of a kidney problem.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Razo IV Injection. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Razo IV Injection during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

UNSAFE
Razo IV Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Razo IV Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney

Kidney

SAFE IF PRESCRIBED
Razo IV Injection is safe to use in patients with kidney disease. No dose adjustment is recommended.
Liver

Liver

CAUTION
Razo IV Injection should be used with caution in patients with severe liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Razo with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Erlotinib (Oral Route)

Do not consume Erlotinib with Rabeprazole. Rabeprazole may reduce blood levels of Erlotinib.
Severe

Methotrexate (Injection Route)

Please consult with your doctor. Doctor may monitor liver function and blood cell counts.
Severe

Methotrexate (Injection Route)

Please consult with your doctor. Doctor may monitor liver function and blood cell counts.
Severe

Methotrexate (Injection Route)

Please consult with your doctor. Doctor may monitor liver function and blood cell counts.
Severe

Methotrexate (Injection Route)

Please consult with your doctor. Doctor may monitor liver function and blood cell counts.

Frequently asked questions

Razo IV Injection is used for the treatment of stomach and intestinal ulcers (gastric and duodenal ulcers), reflux esophagitis or gastroesophageal reflux disease (GERD). It works by reducing the amount of acid made by your stomach and thus relieves your symptoms. Razo IV Injection also prevents acidity associated with use of painkillers and stress ulcers in critically ill people. It is also used to treat a disease associated with excessive acid production in the stomach known as Zollinger Ellison syndrome (ZES). Razo IV Injection is also helpful as a preanesthetic medication (medicine given just before anesthesia) to reduce the chances of aspiration related complications like lung injury.
No, do not stop taking Rekool before completing the full course of treatment. You will start to feel better before your treatment is complete. Razo IV Injection is given into a vein, only if oral administration is not possible, for upto 7 days. As soon as the person is able to take it orally, intravenous administration is stopped and oral form is prescribed. Take Razo IV Injection only as prescribed by your doctor to get maximum benefit.
Yes, Razo IV Injection is relatively safe. Most of the people who take Razo IV Injection do not get a side effect. It is advised to be taken as directed by the doctor for maximum benefits.
Razo IV Injection is used for the treatment of stomach and intestinal ulcers (gastric and duodenal ulcers), reflux esophagitis, or gastroesophageal reflux disease (GERD). It works by reducing the amount of acid made by your stomach and thus relieves your symptoms. Razo IV Injection also prevents acidity associated with the use of painkillers and stress ulcers in critically ill people. It is also used to treat a disease associated with excessive acid production in the stomach known as Zollinger Ellison syndrome (ZES).
Razo IV Injection starts working within an hour of taking it and shows maximum benefit within two to four hours. You should start feeling better within 2 to 3 days but it may take up to 4 weeks to relieve your symptoms significantly.
It is best to take Razo IV Injection before your breakfast. If you are taking two doses, take it in the morning and evening. Razo IV Injection is more effective when it is taken an hour before your food.
Razo IV Injection should be used for as long as it has been prescribed by your doctor. Razo IV Injection is usually considered to be safe when taken in the recommended dose and duration. If Razo IV Injection is used for more than 3 months, certain long-term side effects may be seen. The most important of these is low magnesium levels in your blood, making you feel tired, confused, dizzy, shaky, or dizzy. You may also have muscle twitches or irregular heartbeat. If the use is further prolonged for more than a year, you may have an increased risk of bone fractures, stomach infections, subacute cutaneous lupus erythematosus, osteoporosis, and vitamin B12 deficiency.
Yes, long-term use of Razo IV Injection can cause thinning of bones, which is called osteoporosis. Razo IV Injection decreases the calcium absorption leading to calcium deficiency and increases the risk of bone fractures of the hip, wrist, or spine. Take an adequate amount of calcium in your diet or take the supplements as advised by your doctor to avoid any bone problems.
Yes, vitamin D can be taken along with Razo IV Injection. Vitamin D is generally advised to be taken as a supplement with Razo IV Injection as the long-term use of Razo IV Injection decreases the absorption of calcium and may lead to calcium deficiency. This can lead to osteoporosis (thinning of bones) and increase the risk of bone fractures like hip, wrist, and spine fractures. Please consult your doctor to know about ways to prevent this.
Razo IV Injection is used along with antibiotics for the treatment of H.Pylori infection. It works by decreasing stomach acid volume and decreasing breakdown and washout of antibiotics leading to an increased antibiotic concentration and tissue penetration. It also helps in symptomatic relief by decreasing associated acidity, reflux, and heartburn.
Long-term use of Razo IV Injection can lower magnesium levels in patients taking multiple daily doses for 3 months or longer. Get your magnesium levels checked at regular intervals. Tell your doctor if you experience seizures (fits), dizziness, abnormal or fast heartbeat, jitteriness, jerking movements or shaking (tremors), muscle weakness, spasms of the hands and feet, cramps, muscle aches.
No, do not stop taking Razo IV Injection before completing the full course of treatment. You will start to feel better before your treatment is complete.
Razo IV Injection is best taken 1 hour before a meal. You should avoid spicy and fatty foods while taking this medicine. It also helps to cut down on caffeinated drinks such as tea, coffee, and cola. Alcohol intake should also be avoided as it may worsen your symptoms.
No, alcohol intake is not advised with Razo IV Injection. Alcohol itself does not affect the working of Razo IV Injection, but it can increase acid production. This may further cause worsening of your symptoms.
Yes, you can take antacids along with Razo IV Injection. Take it 2 hours before or after you take Razo IV Injection.
You make see better results if you make certain dietary and lifestyle changes while taking Razo IV Injection. Exercise regularly and eat healthily. You can consult your dietician to get a diet chart that suits you best. Eat at least 3 hours before sleeping to reduce the chances of aggravation of your symptoms at night. You should avoid spicy and fatty foods while taking this medicine. Refrain from caffeinated drinks such as tea, coffee, and cola. Alcohol intake and smoking should also be avoided as they may worsen your symptoms.

Fact Box

Chemical Class

Sulfinylbenzimidazoles

Habit Forming

No

Therapeutic Class

GASTRO INTESTINAL

Action Class

Proton-Pump Inhibitors
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User feedback

Thrice A Day
88%
Twice A Week
12%
Acidity
50%
Stomach ulcers
50%
Excellent
44%
Average
33%
Poor
22%
No Side Effect
25%
Nausea
25%
Flatulence
25%
Vomiting
25%
With or without food
50%
Empty stomach
50%
Expensive
83%
Average
17%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Dr Reddy's Laboratories Ltd
Address: Dr. Reddy's Laboratories Ltd., Village Malpur, P.O.Bhud, Baddi, Dist. Solan, H.P.

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Razo IV Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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